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STEAP3 (STEAP family member 3, metalloreductase)

Identity

Other namesSTMP3
TSAP6
dudlin-2
HGNC (Hugo) STEAP3
LocusID (NCBI) 55240
Location 2q14.2
Location_base_pair Starts at 119981384 and ends at 120023227 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)STEAP3   24592
Entrez_Gene (NCBI)STEAP3  55240  STEAP family member 3, metalloreductase
Cards
GeneCards (Weizmann)STEAP3
Ensembl (Hinxton)ENSG00000115107 [Gene_View]  chr2:119981384-120023227 [Contig_View]  STEAP3 [Vega]
AceView (NCBI)STEAP3
Genatlas (Paris)STEAP3
SOURCE (Stanford)NM_001008410 NM_018234 NM_182915
Genomic and cartography
GoldenPath (UCSC)STEAP3  -  2q14.2   chr2:119981384-120023227 +  2q14.2   [Description]    (hg19-Feb_2009)
EnsemblSTEAP3 - 2q14.2 [CytoView]
Mapping of homologs : NCBISTEAP3 [Mapview]
OMIM609671   
Gene and transcription
Genbank (Entrez)AF238864 AF262322 AF423424 AK001691 AK024163
RefSeq transcript (SRS)NM_001008410 NM_018234 NM_182915
RefSeq transcript (Entrez)NM_001008410 NM_018234 NM_182915
RefSeq genomic (SRS)AC_000134 NC_000002 NC_018913 NT_022135 NW_001838847 NW_004078008
RefSeq genomic (Entrez)AC_000134 NC_000002 NC_018913 NT_022135 NW_001838847 NW_004078008
Consensus coding sequences : CCDS (NCBI)STEAP3
Cluster EST : UnigeneHs.647822 [ SRS ] Hs.647822 [ NCBI ]
CGAP (NCI)Hs.647822
Alternative Splicing : Fast-db (Paris)GSHG0016813
Alternative Splicing GalleryENSG00000115107
Gene ExpressionSTEAP3 [ NCBI-GEO ]   STEAP3 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ658P3 (SRS) Q658P3 (Uniprot)
NextProtQ658P3
With graphics : InterProQ658P3
Splice isoforms : SwissVarQ658P3(Swissvar)
Domains : Interpro (SRS)Fe3_Rdtase_TM_dom    NAD(P)-bd_dom    NADP_OxRdtase_F420   
Domains : Interpro (EBI)Fe3_Rdtase_TM_dom    NAD(P)-bd_dom    NADP_OxRdtase_F420   
Related proteins : CluSTrQ658P3
Domain families : Pfam (SRS)F420_oxidored (PF03807)    Ferric_reduct (PF01794)   
Domain families : Pfam (Sanger)F420_oxidored (PF03807)    Ferric_reduct (PF01794)   
Domain families : Pfam (NCBI)pfam03807    pfam01794   
DMDM55240
Blocks (Seattle)Q658P3
PDB (SRS)2VNS    2VQ3   
PDB (PDBSum)2VNS    2VQ3   
PDB (IMB)2VNS    2VQ3   
PDB (RSDB)2VNS    2VQ3   
Human Protein AtlasENSG00000115107
HPRD10285
IPIIPI00019350   IPI00411628   IPI00845327   IPI00845307   IPI00386348   IPI00917893   
Protein Interaction databases
DIP (DOE-UCLA)Q658P3
IntAct (EBI)Q658P3
FunCoupENSG00000115107
REACTOMESTEAP3
Protein Interaction Database55240
BioGRIDSTEAP3
InParanoidQ658P3
Interologous Interaction database Q658P3
IntegromeDBSTEAP3
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)STEAP3
SNP (GeneSNP Utah)STEAP3
SNP : HGBaseSTEAP3
Genetic variants : HAPMAPSTEAP3
Somatic Mutations in Cancer : COSMICSTEAP3 
CONAN: Copy Number AnalysisSTEAP3 
Mutations and Diseases : HGMDSTEAP3
OMIM609671   
GENETests609671   
Disease Genetic AssociationSTEAP3
Huge Navigator STEAP3 [HugePedia]  STEAP3 [HugeCancerGEM]
Genomic VariantsSTEAP3  STEAP3 [DGVbeta]
snp3D : Map Gene to Disease55240
General knowledge
Homologs : HomoloGeneSTEAP3
Homology/Alignments : Family Browser (UCSC)STEAP3
Phylogenetic Trees/Animal Genes : TreeFamSTEAP3
Catalytic activity : Enzyme1.16.1.- [ Enzyme-Expasy ]   1.16.1.- [ Enzyme-SRS ]   1.16.1.- [ IntEnz-EBI ]   1.16.1.- [ BRENDA ]   1.16.1.- [ KEGG ]   
Chemical/Protein Interactions : CTD55240
Chemical/Pharm GKB GenePA142670863
Clinical trialSTEAP3
Cancer Resource (Charite)ENSG00000115107
Ontology : AmiGOnucleotide binding  ferric-chelate reductase activity  protein binding  multivesicular body  plasma membrane  cellular iron ion homeostasis  apoptotic process  cell cycle  protein secretion  protein secretion  endosome membrane  integral to membrane  transferrin transport  metal ion binding  transmembrane transport  
Ontology : EGO-EBInucleotide binding  ferric-chelate reductase activity  protein binding  multivesicular body  plasma membrane  cellular iron ion homeostasis  apoptotic process  cell cycle  protein secretion  protein secretion  endosome membrane  integral to membrane  transferrin transport  metal ion binding  transmembrane transport  
Other databases
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
PubGeneSTEAP3
iHOPSTEAP3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:34:02 CEST 2013
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