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STIM2 (stromal interaction molecule 2)

Identity

Other alias-
HGNC (Hugo) STIM2
LocusID (NCBI) 57620
Atlas_Id 52904
Location 4p15.2  [Link to chromosome band 4p15]
Location_base_pair Starts at 26862313 and ends at 27027003 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HDAC6 (Xp11.23) / STIM2 (4p15.2)STIM2 (4p15.2) / PPIG (2q31.1)STIM2 (4p15.2) / SPIDR (8q11.21)
STIM2 4p15.2 KIAA0146

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STIM2   19205
Cards
Entrez_Gene (NCBI)STIM2  57620  stromal interaction molecule 2
Aliases
GeneCards (Weizmann)STIM2
Ensembl hg19 (Hinxton)ENSG00000109689 [Gene_View]  chr4:26862313-27027003 [Contig_View]  STIM2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000109689 [Gene_View]  chr4:26862313-27027003 [Contig_View]  STIM2 [Vega]
ICGC DataPortalENSG00000109689
TCGA cBioPortalSTIM2
AceView (NCBI)STIM2
Genatlas (Paris)STIM2
WikiGenes57620
SOURCE (Princeton)STIM2
Genetics Home Reference (NIH)STIM2
Genomic and cartography
GoldenPath hg19 (UCSC)STIM2  -     chr4:26862313-27027003 +  4p15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STIM2  -     4p15.2   [Description]    (hg38-Dec_2013)
EnsemblSTIM2 - 4p15.2 [CytoView hg19]  STIM2 - 4p15.2 [CytoView hg38]
Mapping of homologs : NCBISTIM2 [Mapview hg19]  STIM2 [Mapview hg38]
OMIM610841   
Gene and transcription
Genbank (Entrez)AB040915 AF328905 AK023369 AK096846 AL136577
RefSeq transcript (Entrez)NM_001169117 NM_001169118 NM_020860
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_006316 NW_004929315
Consensus coding sequences : CCDS (NCBI)STIM2
Cluster EST : UnigeneHs.744950 [ NCBI ]
CGAP (NCI)Hs.744950
Alternative Splicing GalleryENSG00000109689
Gene ExpressionSTIM2 [ NCBI-GEO ]   STIM2 [ EBI - ARRAY_EXPRESS ]   STIM2 [ SEEK ]   STIM2 [ MEM ]
Gene Expression Viewer (FireBrowse)STIM2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57620
GTEX Portal (Tissue expression)STIM2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P246   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P246  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P246
Splice isoforms : SwissVarQ9P246
PhosPhoSitePlusQ9P246
Domaine pattern : Prosite (Expaxy)SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)SAM    SAM/pointed    SOAR   
Domain families : Pfam (Sanger)SAM_2 (PF07647)    SOAR (PF16533)   
Domain families : Pfam (NCBI)pfam07647    pfam16533   
Domain families : Smart (EMBL)SAM (SM00454)  
Conserved Domain (NCBI)STIM2
DMDM Disease mutations57620
Blocks (Seattle)STIM2
PDB (SRS)2L5Y   
PDB (PDBSum)2L5Y   
PDB (IMB)2L5Y   
PDB (RSDB)2L5Y   
Structural Biology KnowledgeBase2L5Y   
SCOP (Structural Classification of Proteins)2L5Y   
CATH (Classification of proteins structures)2L5Y   
SuperfamilyQ9P246
Human Protein AtlasENSG00000109689
Peptide AtlasQ9P246
HPRD11609
IPIIPI00946045   IPI00954871   IPI00946838   IPI00945083   IPI00945905   
Protein Interaction databases
DIP (DOE-UCLA)Q9P246
IntAct (EBI)Q9P246
FunCoupENSG00000109689
BioGRIDSTIM2
STRING (EMBL)STIM2
ZODIACSTIM2
Ontologies - Pathways
QuickGOQ9P246
Ontology : AmiGOcalcium channel regulator activity  calcium ion binding  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  cellular calcium ion homeostasis  store-operated calcium channel activity  integral component of membrane  activation of store-operated calcium channel activity  activation of store-operated calcium channel activity  positive regulation of calcium ion transport  positive regulation of calcium ion transport  calcium ion transmembrane transport  
Ontology : EGO-EBIcalcium channel regulator activity  calcium ion binding  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  cellular calcium ion homeostasis  store-operated calcium channel activity  integral component of membrane  activation of store-operated calcium channel activity  activation of store-operated calcium channel activity  positive regulation of calcium ion transport  positive regulation of calcium ion transport  calcium ion transmembrane transport  
Pathways : KEGGCalcium signaling pathway   
NDEx NetworkSTIM2
Atlas of Cancer Signalling NetworkSTIM2
Wikipedia pathwaysSTIM2
Orthology - Evolution
OrthoDB57620
GeneTree (enSembl)ENSG00000109689
Phylogenetic Trees/Animal Genes : TreeFamSTIM2
HOVERGENQ9P246
HOGENOMQ9P246
Homologs : HomoloGeneSTIM2
Homology/Alignments : Family Browser (UCSC)STIM2
Gene fusions - Rearrangements
Fusion : MitelmanSTIM2/SPIDR [4p15.2/8q11.21]  
Fusion: TCGASTIM2 4p15.2 KIAA0146 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTIM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STIM2
dbVarSTIM2
ClinVarSTIM2
1000_GenomesSTIM2 
Exome Variant ServerSTIM2
ExAC (Exome Aggregation Consortium)STIM2 (select the gene name)
Genetic variants : HAPMAP57620
Genomic Variants (DGV)STIM2 [DGVbeta]
DECIPHER (Syndromes)4:26862313-27027003  ENSG00000109689
CONAN: Copy Number AnalysisSTIM2 
Mutations
ICGC Data PortalSTIM2 
TCGA Data PortalSTIM2 
Broad Tumor PortalSTIM2
OASIS PortalSTIM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTIM2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTIM2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STIM2
DgiDB (Drug Gene Interaction Database)STIM2
DoCM (Curated mutations)STIM2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STIM2 (select a term)
intoGenSTIM2
Cancer3DSTIM2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610841   
Orphanet
MedgenSTIM2
Genetic Testing Registry STIM2
NextProtQ9P246 [Medical]
TSGene57620
GENETestsSTIM2
Huge Navigator STIM2 [HugePedia]
snp3D : Map Gene to Disease57620
BioCentury BCIQSTIM2
ClinGenSTIM2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57620
Chemical/Pharm GKB GenePA134926985
Clinical trialSTIM2
Miscellaneous
canSAR (ICR)STIM2 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTIM2
EVEXSTIM2
GoPubMedSTIM2
iHOPSTIM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:21:14 CEST 2017

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