Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57620
MIM: 610841
HGNC: 19205
Ensembl: ENSG00000109689
Variants:
dbSNP: 57620
ClinVar: 57620
TCGA: ENSG00000109689
COSMIC: STIM2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Calcium signaling pathway | KEGG | ko04020 |
| Calcium signaling pathway | KEGG | hsa04020 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38234211 | 2024 | STIM2 is involved in the regulation of apoptosis and the cell cycle in normal and malignant monocytic cells. | 0 |
| 38234211 | 2024 | STIM2 is involved in the regulation of apoptosis and the cell cycle in normal and malignant monocytic cells. | 0 |
| 35022238 | 2022 | Functional communication between IP(3)R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE. | 14 |
| 35818214 | 2022 | STIM2 promotes the invasion and metastasis of breast cancer cells through the NFAT1/TGF-β1 pathway. | 2 |
| 35022238 | 2022 | Functional communication between IP(3)R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE. | 14 |
| 35818214 | 2022 | STIM2 promotes the invasion and metastasis of breast cancer cells through the NFAT1/TGF-β1 pathway. | 2 |
| 32012922 | 2020 | Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration. | 3 |
| 32186932 | 2020 | Notch enhances Ca(2+) entry by activating calcium-sensing receptors and inhibiting voltage-gated K(+) channels. | 13 |
| 32576932 | 2020 | Synergistic stabilization by nitrosoglutathione-induced thiol modifications in the stromal interaction molecule-2 luminal domain suppresses basal and store operated calcium entry. | 3 |
| 32601188 | 2020 | STIM2 targets Orai1/STIM1 to the AKAP79 signaling complex and confers coupling of Ca(2+) entry with NFAT1 activation. | 16 |
| 32641503 | 2020 | L-type Ca(2+) channel blockers promote vascular remodeling through activation of STIM proteins. | 25 |
| 32794568 | 2020 | Functional role of TRPC6 and STIM2 in cytosolic and endoplasmic reticulum Ca2+ content in resting estrogen receptor-positive breast cancer cells. | 12 |
| 33027906 | 2020 | Calmodulin Binding Proteins and Alzheimer's Disease: Biomarkers, Regulatory Enzymes and Receptors That Are Regulated by Calmodulin. | 24 |
| 33086068 | 2020 | Oxidative Stress-Induced STIM2 Cysteine Modifications Suppress Store-Operated Calcium Entry. | 14 |
| 32012922 | 2020 | Transgenic Mice Overexpressing Human STIM2 and ORAI1 in Neurons Exhibit Changes in Behavior and Calcium Homeostasis but Show No Signs of Neurodegeneration. | 3 |
Citation
Dessen P
STIM2 (stromal interaction molecule 2)
Atlas Genet Cytogenet Oncol Haematol. 2012-10-01
Online version: http://atlasgeneticsoncology.org/gene/52904/stim2
