STK25 (serine/threonine kinase 25)

2006-10-01  

Identity

HGNC
LOCATION
2q37.3
LOCUSID
ALIAS
SOK1,YSK1
FUSION GENES

Other Information

Locus ID:

NCBI: 10494
MIM: 602255
HGNC: 11404
Ensembl: ENSG00000115694

Variants:

dbSNP: 10494
ClinVar: 10494
TCGA: ENSG00000115694
COSMIC: STK25

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115694ENST00000316586O00506
ENSG00000115694ENST00000316586A0A024R4B2
ENSG00000115694ENST00000401869O00506
ENSG00000115694ENST00000401869A0A024R4B2
ENSG00000115694ENST00000403346O00506
ENSG00000115694ENST00000403346A0A024R4B2
ENSG00000115694ENST00000405585O00506
ENSG00000115694ENST00000405585A0A0S2Z4Y2
ENSG00000115694ENST00000405883O00506
ENSG00000115694ENST00000405883A0A0S2Z4Y2
ENSG00000115694ENST00000413760C9JDH9
ENSG00000115694ENST00000420551C9JFA1
ENSG00000115694ENST00000423004H7C279
ENSG00000115694ENST00000424537C9J6L2
ENSG00000115694ENST00000426941C9JN58
ENSG00000115694ENST00000429279C9JJV0
ENSG00000115694ENST00000435225C9K0M6
ENSG00000115694ENST00000436402E7EM58
ENSG00000115694ENST00000439101C9J8E8
ENSG00000115694ENST00000440109C9JIH8
ENSG00000115694ENST00000442307C9JCC0
ENSG00000115694ENST00000450497C9J232
ENSG00000115694ENST00000535007O00506
ENSG00000115694ENST00000543554O00506

Expression (GTEx)

0
50
100
150

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
150376012004YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3zeta.110
172539632007A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.108
205924722010CCM3 signaling through sterile 20-like kinases plays an essential role during zebrafish cardiovascular development and cerebral cavernous malformations.65
238892532013SOcK, MiSTs, MASK and STicKs: the GCKIII (germinal centre kinase III) kinases and their heterologous protein-protein interactions.19
183643532008SOK1 translocates from the Golgi to the nucleus upon chemical anoxia and induces apoptotic cell death.18
226527802012PDCD10 interacts with STK25 to accelerate cell apoptosis under oxidative stress.14
223919492012Serine/threonine protein kinase 25 (STK25): a novel negative regulator of lipid and glucose metabolism in rodent and human skeletal muscle.10
227828922012STK25 protein mediates TrkA and CCM2 protein-dependent death in pediatric tumor cells of neural origin.9
255508582014Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer.7
265530962016Protein kinase STK25 controls lipid partitioning in hepatocytes and correlates with liver fat content in humans.7

Citation

Dessen P

STK25 (serine/threonine kinase 25)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43510/stk25