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STK33 (serine/threonine kinase 33)

Identity

Alias (NCBI)-
HGNC (Hugo) STK33
LocusID (NCBI) 65975
Atlas_Id 43513
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 8391870 and ends at 8593976 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ALX4 (11p11.2) / STK33 (11p15.4)B3GLCT (13q12.3) / STK33 (11p15.4)ALX4 11p11.2 / STK33 11p15.4
B3GALTL STK33 11p15.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STK33   14568
Cards
Entrez_Gene (NCBI)STK33    serine/threonine kinase 33
Aliases
GeneCards (Weizmann)STK33
Ensembl hg19 (Hinxton)ENSG00000130413 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130413 [Gene_View]  ENSG00000130413 [Sequence]  chr11:8391870-8593976 [Contig_View]  STK33 [Vega]
ICGC DataPortalENSG00000130413
TCGA cBioPortalSTK33
AceView (NCBI)STK33
Genatlas (Paris)STK33
SOURCE (Princeton)STK33
Genetics Home Reference (NIH)STK33
Genomic and cartography
GoldenPath hg38 (UCSC)STK33  -     chr11:8391870-8593976 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STK33  -     11p15.4   [Description]    (hg19-Feb_2009)
GoldenPathSTK33 - 11p15.4 [CytoView hg19]  STK33 - 11p15.4 [CytoView hg38]
ImmunoBaseENSG00000130413
Genome Data Viewer NCBISTK33 [Mapview hg19]  
OMIM607670   
Gene and transcription
Genbank (Entrez)AJ303380 AK092720 AK093251 AK122808 AK293193
RefSeq transcript (Entrez)NM_001289058 NM_001289059 NM_001289061 NM_001352387 NM_001352388 NM_001352389 NM_001352390 NM_001352391 NM_001352392 NM_001352393 NM_001352394 NM_001352395 NM_001352396 NM_001352397 NM_001352398 NM_001352399 NM_030906
Consensus coding sequences : CCDS (NCBI)STK33
Gene ExpressionSTK33 [ NCBI-GEO ]   STK33 [ EBI - ARRAY_EXPRESS ]   STK33 [ SEEK ]   STK33 [ MEM ]
Gene Expression Viewer (FireBrowse)STK33 [ Firebrowse - Broad ]
GenevisibleExpression of STK33 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65975
GTEX Portal (Tissue expression)STK33
Human Protein AtlasENSG00000130413-STK33 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYT3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYT3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYT3
PhosPhoSitePlusQ9BYT3
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom_sf    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)STK33
SuperfamilyQ9BYT3
AlphaFold pdb e-kbQ9BYT3   
Human Protein Atlas [tissue]ENSG00000130413-STK33 [tissue]
HPRD09642
Protein Interaction databases
DIP (DOE-UCLA)Q9BYT3
IntAct (EBI)Q9BYT3
BioGRIDSTK33
STRING (EMBL)STK33
ZODIACSTK33
Ontologies - Pathways
QuickGOQ9BYT3
Ontology : AmiGOprotein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  nucleus  cytoplasm  signal transduction in response to DNA damage  mitotic DNA damage checkpoint signaling  protein autophosphorylation  perinuclear region of cytoplasm  protein serine kinase activity  protein threonine kinase activity  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  nucleus  cytoplasm  signal transduction in response to DNA damage  mitotic DNA damage checkpoint signaling  protein autophosphorylation  perinuclear region of cytoplasm  protein serine kinase activity  protein threonine kinase activity  
NDEx NetworkSTK33
Atlas of Cancer Signalling NetworkSTK33
Wikipedia pathwaysSTK33
Orthology - Evolution
OrthoDB65975
GeneTree (enSembl)ENSG00000130413
Phylogenetic Trees/Animal Genes : TreeFamSTK33
Homologs : HomoloGeneSTK33
Homology/Alignments : Family Browser (UCSC)STK33
Gene fusions - Rearrangements
Fusion : MitelmanALX4/STK33 [11p11.2/11p15.4]  
Fusion : MitelmanB3GLCT/STK33 [13q12.3/11p15.4]  
Fusion : QuiverSTK33
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK33
dbVarSTK33
ClinVarSTK33
MonarchSTK33
1000_GenomesSTK33 
Exome Variant ServerSTK33
GNOMAD BrowserENSG00000130413
Varsome BrowserSTK33
ACMGSTK33 variants
VarityQ9BYT3
Genomic Variants (DGV)STK33 [DGVbeta]
DECIPHERSTK33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTK33 
Mutations
ICGC Data PortalSTK33 
TCGA Data PortalSTK33 
Broad Tumor PortalSTK33
OASIS PortalSTK33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK33  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTK33
Mutations and Diseases : HGMDSTK33
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTK33
DgiDB (Drug Gene Interaction Database)STK33
DoCM (Curated mutations)STK33
CIViC (Clinical Interpretations of Variants in Cancer)STK33
Cancer3DSTK33
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607670   
Orphanet
DisGeNETSTK33
MedgenSTK33
Genetic Testing Registry STK33
NextProtQ9BYT3 [Medical]
GENETestsSTK33
Target ValidationSTK33
Huge Navigator STK33 [HugePedia]
ClinGenSTK33
Clinical trials, drugs, therapy
MyCancerGenomeSTK33
Protein Interactions : CTDSTK33
Pharm GKB GenePA37900
PharosQ9BYT3
Clinical trialSTK33
Miscellaneous
canSAR (ICR)STK33
HarmonizomeSTK33
DataMed IndexSTK33
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTK33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:33:37 CEST 2021

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