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STK33 (serine/threonine kinase 33)

Identity

Other alias-
HGNC (Hugo) STK33
LocusID (NCBI) 65975
Atlas_Id 43513
Location 11p15.4  [Link to chromosome band 11p15]
Location_base_pair Starts at 8391866 and ends at 8594289 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ALX4 (11p11.2) / STK33 (11p15.4)B3GLCT (13q12.3) / STK33 (11p15.4)ALX4 11p11.2 / STK33 11p15.4
B3GALTL STK33 11p15.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STK33   14568
Cards
Entrez_Gene (NCBI)STK33  65975  serine/threonine kinase 33
Aliases
GeneCards (Weizmann)STK33
Ensembl hg19 (Hinxton)ENSG00000130413 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000130413 [Gene_View]  chr11:8391866-8594289 [Contig_View]  STK33 [Vega]
ICGC DataPortalENSG00000130413
TCGA cBioPortalSTK33
AceView (NCBI)STK33
Genatlas (Paris)STK33
WikiGenes65975
SOURCE (Princeton)STK33
Genetics Home Reference (NIH)STK33
Genomic and cartography
GoldenPath hg38 (UCSC)STK33  -     chr11:8391866-8594289 -  11p15.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STK33  -     11p15.4   [Description]    (hg19-Feb_2009)
EnsemblSTK33 - 11p15.4 [CytoView hg19]  STK33 - 11p15.4 [CytoView hg38]
Mapping of homologs : NCBISTK33 [Mapview hg19]  STK33 [Mapview hg38]
OMIM607670   
Gene and transcription
Genbank (Entrez)AJ303380 AK092720 AK093251 AK122808 AK293193
RefSeq transcript (Entrez)NM_001289058 NM_001289059 NM_001289061 NM_030906
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STK33
Cluster EST : UnigeneHs.501833 [ NCBI ]
CGAP (NCI)Hs.501833
Alternative Splicing GalleryENSG00000130413
Gene ExpressionSTK33 [ NCBI-GEO ]   STK33 [ EBI - ARRAY_EXPRESS ]   STK33 [ SEEK ]   STK33 [ MEM ]
Gene Expression Viewer (FireBrowse)STK33 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65975
GTEX Portal (Tissue expression)STK33
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BYT3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BYT3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BYT3
Splice isoforms : SwissVarQ9BYT3
PhosPhoSitePlusQ9BYT3
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)STK33
DMDM Disease mutations65975
Blocks (Seattle)STK33
SuperfamilyQ9BYT3
Human Protein AtlasENSG00000130413
Peptide AtlasQ9BYT3
HPRD09642
IPIIPI00302351   IPI00747557   IPI00795522   IPI00793800   IPI00796654   IPI00797799   IPI00796021   IPI00973841   IPI00982678   IPI01011520   IPI01011973   
Protein Interaction databases
DIP (DOE-UCLA)Q9BYT3
IntAct (EBI)Q9BYT3
FunCoupENSG00000130413
BioGRIDSTK33
STRING (EMBL)STK33
ZODIACSTK33
Ontologies - Pathways
QuickGOQ9BYT3
Ontology : AmiGOprotein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  intracellular  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  intracellular signal transduction  protein autophosphorylation  perinuclear region of cytoplasm  
Ontology : EGO-EBIprotein serine/threonine kinase activity  protein serine/threonine kinase activity  ATP binding  intracellular  peptidyl-serine phosphorylation  peptidyl-threonine phosphorylation  intracellular signal transduction  protein autophosphorylation  perinuclear region of cytoplasm  
NDEx NetworkSTK33
Atlas of Cancer Signalling NetworkSTK33
Wikipedia pathwaysSTK33
Orthology - Evolution
OrthoDB65975
GeneTree (enSembl)ENSG00000130413
Phylogenetic Trees/Animal Genes : TreeFamSTK33
HOVERGENQ9BYT3
HOGENOMQ9BYT3
Homologs : HomoloGeneSTK33
Homology/Alignments : Family Browser (UCSC)STK33
Gene fusions - Rearrangements
Fusion : MitelmanALX4/STK33 [11p11.2/11p15.4]  [t(11;11)(p11;p15)]  
Fusion : MitelmanB3GLCT/STK33 [13q12.3/11p15.4]  [t(11;13)(p15;q12)]  
Fusion: TCGAALX4 11p11.2 STK33 11p15.4 BRCA
Fusion: TCGAB3GALTL STK33 11p15.4 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK33 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK33
dbVarSTK33
ClinVarSTK33
1000_GenomesSTK33 
Exome Variant ServerSTK33
ExAC (Exome Aggregation Consortium)STK33 (select the gene name)
Genetic variants : HAPMAP65975
Genomic Variants (DGV)STK33 [DGVbeta]
DECIPHERSTK33 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTK33 
Mutations
ICGC Data PortalSTK33 
TCGA Data PortalSTK33 
Broad Tumor PortalSTK33
OASIS PortalSTK33 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK33  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTK33
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STK33
DgiDB (Drug Gene Interaction Database)STK33
DoCM (Curated mutations)STK33 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STK33 (select a term)
intoGenSTK33
Cancer3DSTK33(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607670   
Orphanet
MedgenSTK33
Genetic Testing Registry STK33
NextProtQ9BYT3 [Medical]
TSGene65975
GENETestsSTK33
Target ValidationSTK33
Huge Navigator STK33 [HugePedia]
snp3D : Map Gene to Disease65975
BioCentury BCIQSTK33
ClinGenSTK33
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65975
Chemical/Pharm GKB GenePA37900
Clinical trialSTK33
Miscellaneous
canSAR (ICR)STK33 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTK33
EVEXSTK33
GoPubMedSTK33
iHOPSTK33
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:15:59 CEST 2017

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