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STK35 (serine/threonine kinase 35)

Identity

Alias_symbol (synonym)bA550O8.2
CLIK1
Other aliasSTK35L1
HGNC (Hugo) STK35
LocusID (NCBI) 140901
Atlas_Id 43514
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 2101882 and ends at 2148552 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
STK35 (20p13) / CHD6 (20q12)STK35 20p13 / CHD6 20q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STK35   16254
Cards
Entrez_Gene (NCBI)STK35  140901  serine/threonine kinase 35
AliasesCLIK1; STK35L1
GeneCards (Weizmann)STK35
Ensembl hg19 (Hinxton)ENSG00000125834 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125834 [Gene_View]  chr20:2101882-2148552 [Contig_View]  STK35 [Vega]
ICGC DataPortalENSG00000125834
TCGA cBioPortalSTK35
AceView (NCBI)STK35
Genatlas (Paris)STK35
WikiGenes140901
SOURCE (Princeton)STK35
Genetics Home Reference (NIH)STK35
Genomic and cartography
GoldenPath hg38 (UCSC)STK35  -     chr20:2101882-2148552 +  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STK35  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblSTK35 - 20p13 [CytoView hg19]  STK35 - 20p13 [CytoView hg38]
Mapping of homologs : NCBISTK35 [Mapview hg19]  STK35 [Mapview hg38]
OMIM609370   
Gene and transcription
Genbank (Entrez)AF195026 AK024394 AK026555 AK302629 AK314728
RefSeq transcript (Entrez)NM_080836
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STK35
Cluster EST : UnigeneHs.100057 [ NCBI ]
CGAP (NCI)Hs.100057
Alternative Splicing GalleryENSG00000125834
Gene ExpressionSTK35 [ NCBI-GEO ]   STK35 [ EBI - ARRAY_EXPRESS ]   STK35 [ SEEK ]   STK35 [ MEM ]
Gene Expression Viewer (FireBrowse)STK35 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)140901
GTEX Portal (Tissue expression)STK35
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDR2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDR2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDR2
Splice isoforms : SwissVarQ8TDR2
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ8TDR2
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Domain families : Smart (EMBL)S_TKc (SM00220)  
Conserved Domain (NCBI)STK35
DMDM Disease mutations140901
Blocks (Seattle)STK35
SuperfamilyQ8TDR2
Human Protein AtlasENSG00000125834
Peptide AtlasQ8TDR2
HPRD11612
IPIIPI00291457   IPI00908708   IPI00964435   
Protein Interaction databases
DIP (DOE-UCLA)Q8TDR2
IntAct (EBI)Q8TDR2
FunCoupENSG00000125834
BioGRIDSTK35
STRING (EMBL)STK35
ZODIACSTK35
Ontologies - Pathways
QuickGOQ8TDR2
Ontology : AmiGOprotein serine/threonine kinase activity  ATP binding  nucleus  nucleolus  cytoplasm  protein phosphorylation  nuclear body  
Ontology : EGO-EBIprotein serine/threonine kinase activity  ATP binding  nucleus  nucleolus  cytoplasm  protein phosphorylation  nuclear body  
NDEx NetworkSTK35
Atlas of Cancer Signalling NetworkSTK35
Wikipedia pathwaysSTK35
Orthology - Evolution
OrthoDB140901
GeneTree (enSembl)ENSG00000125834
Phylogenetic Trees/Animal Genes : TreeFamSTK35
HOVERGENQ8TDR2
HOGENOMQ8TDR2
Homologs : HomoloGeneSTK35
Homology/Alignments : Family Browser (UCSC)STK35
Gene fusions - Rearrangements
Fusion: TCGASTK35 20p13 CHD6 20q12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK35 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK35
dbVarSTK35
ClinVarSTK35
1000_GenomesSTK35 
Exome Variant ServerSTK35
ExAC (Exome Aggregation Consortium)STK35 (select the gene name)
Genetic variants : HAPMAP140901
Genomic Variants (DGV)STK35 [DGVbeta]
DECIPHERSTK35 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTK35 
Mutations
ICGC Data PortalSTK35 
TCGA Data PortalSTK35 
Broad Tumor PortalSTK35
OASIS PortalSTK35 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK35  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTK35
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STK35
DgiDB (Drug Gene Interaction Database)STK35
DoCM (Curated mutations)STK35 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STK35 (select a term)
intoGenSTK35
Cancer3DSTK35(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609370   
Orphanet
MedgenSTK35
Genetic Testing Registry STK35
NextProtQ8TDR2 [Medical]
TSGene140901
GENETestsSTK35
Target ValidationSTK35
Huge Navigator STK35 [HugePedia]
snp3D : Map Gene to Disease140901
BioCentury BCIQSTK35
ClinGenSTK35
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD140901
Chemical/Pharm GKB GenePA38097
Clinical trialSTK35
Miscellaneous
canSAR (ICR)STK35 (select the gene name)
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTK35
EVEXSTK35
GoPubMedSTK35
iHOPSTK35
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:57:56 CEST 2017

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