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STK38 (serine/threonine kinase 38)

Identity

Alias_symbol (synonym)NDR
Other aliasNDR1
HGNC (Hugo) STK38
LocusID (NCBI) 11329
Atlas_Id 43516
Location 6p21.31  [Link to chromosome band 6p21]
Location_base_pair Starts at 36493883 and ends at 36547516 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
KCTD20 (6p21.31) / STK38 (6p21.31)STK38 (6p21.31) / RBM6 (3p21.31)KCTD20 6p21.31 / STK38 6p21.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STK38   17847
Cards
Entrez_Gene (NCBI)STK38  11329  serine/threonine kinase 38
AliasesNDR; NDR1
GeneCards (Weizmann)STK38
Ensembl hg19 (Hinxton)ENSG00000112079 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112079 [Gene_View]  chr6:36493883-36547516 [Contig_View]  STK38 [Vega]
ICGC DataPortalENSG00000112079
TCGA cBioPortalSTK38
AceView (NCBI)STK38
Genatlas (Paris)STK38
WikiGenes11329
SOURCE (Princeton)STK38
Genetics Home Reference (NIH)STK38
Genomic and cartography
GoldenPath hg38 (UCSC)STK38  -     chr6:36493883-36547516 -  6p21.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STK38  -     6p21.31   [Description]    (hg19-Feb_2009)
EnsemblSTK38 - 6p21.31 [CytoView hg19]  STK38 - 6p21.31 [CytoView hg38]
Mapping of homologs : NCBISTK38 [Mapview hg19]  STK38 [Mapview hg38]
OMIM606964   
Gene and transcription
Genbank (Entrez)AF034187 AF034188 AK095337 AK312559 BC012085
RefSeq transcript (Entrez)NM_001305102 NM_007271
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STK38
Cluster EST : UnigeneHs.409578 [ NCBI ]
CGAP (NCI)Hs.409578
Alternative Splicing GalleryENSG00000112079
Gene ExpressionSTK38 [ NCBI-GEO ]   STK38 [ EBI - ARRAY_EXPRESS ]   STK38 [ SEEK ]   STK38 [ MEM ]
Gene Expression Viewer (FireBrowse)STK38 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11329
GTEX Portal (Tissue expression)STK38
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15208   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15208  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15208
Splice isoforms : SwissVarQ15208
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ15208
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom    Pkinase_C    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)    Pkinase_C (PF00433)   
Domain families : Pfam (NCBI)pfam00069    pfam00433   
Domain families : Smart (EMBL)S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)STK38
DMDM Disease mutations11329
Blocks (Seattle)STK38
PDB (SRS)1PSB   
PDB (PDBSum)1PSB   
PDB (IMB)1PSB   
PDB (RSDB)1PSB   
Structural Biology KnowledgeBase1PSB   
SCOP (Structural Classification of Proteins)1PSB   
CATH (Classification of proteins structures)1PSB   
SuperfamilyQ15208
Human Protein AtlasENSG00000112079
Peptide AtlasQ15208
HPRD09511
IPIIPI00027251   
Protein Interaction databases
DIP (DOE-UCLA)Q15208
IntAct (EBI)Q15208
FunCoupENSG00000112079
BioGRIDSTK38
STRING (EMBL)STK38
ZODIACSTK38
Ontologies - Pathways
QuickGOQ15208
Ontology : AmiGOmagnesium ion binding  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  cellular protein modification process  protein phosphorylation  peptidyl-serine phosphorylation  mitogen-activated protein kinase kinase kinase binding  intracellular signal transduction  negative regulation of MAP kinase activity  cadherin binding  
Ontology : EGO-EBImagnesium ion binding  protein serine/threonine kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  cellular protein modification process  protein phosphorylation  peptidyl-serine phosphorylation  mitogen-activated protein kinase kinase kinase binding  intracellular signal transduction  negative regulation of MAP kinase activity  cadherin binding  
NDEx NetworkSTK38
Atlas of Cancer Signalling NetworkSTK38
Wikipedia pathwaysSTK38
Orthology - Evolution
OrthoDB11329
GeneTree (enSembl)ENSG00000112079
Phylogenetic Trees/Animal Genes : TreeFamSTK38
HOVERGENQ15208
HOGENOMQ15208
Homologs : HomoloGeneSTK38
Homology/Alignments : Family Browser (UCSC)STK38
Gene fusions - Rearrangements
Fusion : MitelmanKCTD20/STK38 [6p21.31/6p21.31]  [t(6;6)(p21;p21)]  
Fusion: TCGAKCTD20 6p21.31 STK38 6p21.31 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK38 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK38
dbVarSTK38
ClinVarSTK38
1000_GenomesSTK38 
Exome Variant ServerSTK38
ExAC (Exome Aggregation Consortium)STK38 (select the gene name)
Genetic variants : HAPMAP11329
Genomic Variants (DGV)STK38 [DGVbeta]
DECIPHERSTK38 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTK38 
Mutations
ICGC Data PortalSTK38 
TCGA Data PortalSTK38 
Broad Tumor PortalSTK38
OASIS PortalSTK38 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK38  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTK38
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STK38
DgiDB (Drug Gene Interaction Database)STK38
DoCM (Curated mutations)STK38 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STK38 (select a term)
intoGenSTK38
Cancer3DSTK38(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606964   
Orphanet
MedgenSTK38
Genetic Testing Registry STK38
NextProtQ15208 [Medical]
TSGene11329
GENETestsSTK38
Target ValidationSTK38
Huge Navigator STK38 [HugePedia]
snp3D : Map Gene to Disease11329
BioCentury BCIQSTK38
ClinGenSTK38
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11329
Chemical/Pharm GKB GenePA38251
Clinical trialSTK38
Miscellaneous
canSAR (ICR)STK38 (select the gene name)
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTK38
EVEXSTK38
GoPubMedSTK38
iHOPSTK38
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 1 17:16:00 CEST 2017

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