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STK38L (serine/threonine kinase 38 like)

Identity

Alias (NCBI)NDR2
HGNC (Hugo) STK38L
HGNC Alias symbKIAA0965
NDR2
HGNC Alias namenuclear Dbf2-related 2
LocusID (NCBI) 23012
Atlas_Id 43517
Location 12p11.23  [Link to chromosome band 12p11]
Location_base_pair Starts at 27244286 and ends at 27325957 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GNAS (20q13.32) / STK38L (12p11.23)MRPS35 (12p11.22) / STK38L (12p11.23)NAP1L1 (12q21.2) / STK38L (12p11.23)
STK38L (12p11.23) / ALB (4q13.3)WNK1 (12p13.33) / STK38L (12p11.23)NAP1L1 12q21.2 / STK38L 12p11.23
WNK1 12p13.33 / STK38L 12p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STK38L   17848
Cards
Entrez_Gene (NCBI)STK38L    serine/threonine kinase 38 like
AliasesNDR2
GeneCards (Weizmann)STK38L
Ensembl hg19 (Hinxton)ENSG00000211455 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000211455 [Gene_View]  ENSG00000211455 [Sequence]  chr12:27244286-27325957 [Contig_View]  STK38L [Vega]
ICGC DataPortalENSG00000211455
TCGA cBioPortalSTK38L
AceView (NCBI)STK38L
Genatlas (Paris)STK38L
SOURCE (Princeton)STK38L
Genetics Home Reference (NIH)STK38L
Genomic and cartography
GoldenPath hg38 (UCSC)STK38L  -     chr12:27244286-27325957 +  12p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STK38L  -     12p11.23   [Description]    (hg19-Feb_2009)
GoldenPathSTK38L - 12p11.23 [CytoView hg19]  STK38L - 12p11.23 [CytoView hg38]
ImmunoBaseENSG00000211455
Genome Data Viewer NCBISTK38L [Mapview hg19]  
OMIM615836   
Gene and transcription
Genbank (Entrez)AB023182 AK291055 AK303373 AK304755 AK304862
RefSeq transcript (Entrez)NM_015000
Consensus coding sequences : CCDS (NCBI)STK38L
Gene ExpressionSTK38L [ NCBI-GEO ]   STK38L [ EBI - ARRAY_EXPRESS ]   STK38L [ SEEK ]   STK38L [ MEM ]
Gene Expression Viewer (FireBrowse)STK38L [ Firebrowse - Broad ]
GenevisibleExpression of STK38L in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23012
GTEX Portal (Tissue expression)STK38L
Human Protein AtlasENSG00000211455-STK38L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2H1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2H1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2H1
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9Y2H1
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom_sf    Pkinase_C    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)    Pkinase_C (PF00433)   
Domain families : Pfam (NCBI)pfam00069    pfam00433   
Domain families : Smart (EMBL)S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)STK38L
PDB (RSDB)5XQZ   
PDB Europe5XQZ   
PDB (PDBSum)5XQZ   
PDB (IMB)5XQZ   
Structural Biology KnowledgeBase5XQZ   
SCOP (Structural Classification of Proteins)5XQZ   
CATH (Classification of proteins structures)5XQZ   
SuperfamilyQ9Y2H1
AlphaFold pdb e-kbQ9Y2H1   
Human Protein Atlas [tissue]ENSG00000211455-STK38L [tissue]
HPRD10256
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2H1
IntAct (EBI)Q9Y2H1
BioGRIDSTK38L
STRING (EMBL)STK38L
ZODIACSTK38L
Ontologies - Pathways
QuickGOQ9Y2H1
Ontology : AmiGOmagnesium ion binding  actin binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  cytosol  protein phosphorylation  protein phosphorylation  actin cytoskeleton  membrane  peptidyl-serine phosphorylation  intracellular signal transduction  intracellular signal transduction  regulation of cellular component organization  protein serine kinase activity  protein threonine kinase activity  
Ontology : EGO-EBImagnesium ion binding  actin binding  protein serine/threonine kinase activity  protein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  cytosol  protein phosphorylation  protein phosphorylation  actin cytoskeleton  membrane  peptidyl-serine phosphorylation  intracellular signal transduction  intracellular signal transduction  regulation of cellular component organization  protein serine kinase activity  protein threonine kinase activity  
NDEx NetworkSTK38L
Atlas of Cancer Signalling NetworkSTK38L
Wikipedia pathwaysSTK38L
Orthology - Evolution
OrthoDB23012
GeneTree (enSembl)ENSG00000211455
Phylogenetic Trees/Animal Genes : TreeFamSTK38L
Homologs : HomoloGeneSTK38L
Homology/Alignments : Family Browser (UCSC)STK38L
Gene fusions - Rearrangements
Fusion : MitelmanNAP1L1/STK38L [12q21.2/12p11.23]  
Fusion : MitelmanWNK1/STK38L [12p13.33/12p11.23]  
Fusion : QuiverSTK38L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK38L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK38L
dbVarSTK38L
ClinVarSTK38L
MonarchSTK38L
1000_GenomesSTK38L 
Exome Variant ServerSTK38L
GNOMAD BrowserENSG00000211455
Varsome BrowserSTK38L
ACMGSTK38L variants
VarityQ9Y2H1
Genomic Variants (DGV)STK38L [DGVbeta]
DECIPHERSTK38L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTK38L 
Mutations
ICGC Data PortalSTK38L 
TCGA Data PortalSTK38L 
Broad Tumor PortalSTK38L
OASIS PortalSTK38L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK38L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTK38L
Mutations and Diseases : HGMDSTK38L
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTK38L
DgiDB (Drug Gene Interaction Database)STK38L
DoCM (Curated mutations)STK38L
CIViC (Clinical Interpretations of Variants in Cancer)STK38L
Cancer3DSTK38L
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615836   
Orphanet
DisGeNETSTK38L
MedgenSTK38L
Genetic Testing Registry STK38L
NextProtQ9Y2H1 [Medical]
GENETestsSTK38L
Target ValidationSTK38L
Huge Navigator STK38L [HugePedia]
ClinGenSTK38L
Clinical trials, drugs, therapy
MyCancerGenomeSTK38L
Protein Interactions : CTDSTK38L
Pharm GKB GenePA38252
PharosQ9Y2H1
Clinical trialSTK38L
Miscellaneous
canSAR (ICR)STK38L
HarmonizomeSTK38L
DataMed IndexSTK38L
Probes
Litterature
PubMed59 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTK38L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:33:38 CEST 2021

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