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STK38L (serine/threonine kinase 38 like)

Identity

Alias_symbol (synonym)KIAA0965
NDR2
Other alias
HGNC (Hugo) STK38L
LocusID (NCBI) 23012
Atlas_Id 43517
Location 12p11.23  [Link to chromosome band 12p11]
Location_base_pair Starts at 27397078 and ends at 27478890 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
GNAS (20q13.32) / STK38L (12p11.23)MRPS35 (12p11.22) / STK38L (12p11.23)NAP1L1 (12q21.2) / STK38L (12p11.23)
STK38L (12p11.23) / ALB (4q13.3)WNK1 (12p13.33) / STK38L (12p11.23)NAP1L1 12q21.2 / STK38L 12p11.23
WNK1 12p13.33 / STK38L 12p11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STK38L   17848
Cards
Entrez_Gene (NCBI)STK38L  23012  serine/threonine kinase 38 like
AliasesNDR2
GeneCards (Weizmann)STK38L
Ensembl hg19 (Hinxton)ENSG00000211455 [Gene_View]  chr12:27397078-27478890 [Contig_View]  STK38L [Vega]
Ensembl hg38 (Hinxton)ENSG00000211455 [Gene_View]  chr12:27397078-27478890 [Contig_View]  STK38L [Vega]
ICGC DataPortalENSG00000211455
TCGA cBioPortalSTK38L
AceView (NCBI)STK38L
Genatlas (Paris)STK38L
WikiGenes23012
SOURCE (Princeton)STK38L
Genetics Home Reference (NIH)STK38L
Genomic and cartography
GoldenPath hg19 (UCSC)STK38L  -     chr12:27397078-27478890 +  12p11.23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STK38L  -     12p11.23   [Description]    (hg38-Dec_2013)
EnsemblSTK38L - 12p11.23 [CytoView hg19]  STK38L - 12p11.23 [CytoView hg38]
Mapping of homologs : NCBISTK38L [Mapview hg19]  STK38L [Mapview hg38]
OMIM615836   
Gene and transcription
Genbank (Entrez)AB023182 AK291055 AK303373 AK304755 AK304862
RefSeq transcript (Entrez)NM_015000
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)STK38L
Cluster EST : UnigeneHs.184523 [ NCBI ]
CGAP (NCI)Hs.184523
Alternative Splicing GalleryENSG00000211455
Gene ExpressionSTK38L [ NCBI-GEO ]   STK38L [ EBI - ARRAY_EXPRESS ]   STK38L [ SEEK ]   STK38L [ MEM ]
Gene Expression Viewer (FireBrowse)STK38L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23012
GTEX Portal (Tissue expression)STK38L
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y2H1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y2H1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y2H1
Splice isoforms : SwissVarQ9Y2H1
Catalytic activity : Enzyme2.7.11.1 [ Enzyme-Expasy ]   2.7.11.12.7.11.1 [ IntEnz-EBI ]   2.7.11.1 [ BRENDA ]   2.7.11.1 [ KEGG ]   
PhosPhoSitePlusQ9Y2H1
Domaine pattern : Prosite (Expaxy)AGC_KINASE_CTER (PS51285)    PROTEIN_KINASE_ATP (PS00107)    PROTEIN_KINASE_DOM (PS50011)    PROTEIN_KINASE_ST (PS00108)   
Domains : Interpro (EBI)AGC-kinase_C    Kinase-like_dom    Pkinase_C    Prot_kinase_dom    Protein_kinase_ATP_BS    Ser/Thr_dual-sp_kinase    Ser/Thr_kinase_AS   
Domain families : Pfam (Sanger)Pkinase (PF00069)    Pkinase_C (PF00433)   
Domain families : Pfam (NCBI)pfam00069    pfam00433   
Domain families : Smart (EMBL)S_TK_X (SM00133)  S_TKc (SM00220)  
Conserved Domain (NCBI)STK38L
DMDM Disease mutations23012
Blocks (Seattle)STK38L
SuperfamilyQ9Y2H1
Human Protein AtlasENSG00000211455
Peptide AtlasQ9Y2H1
HPRD10256
IPIIPI00237011   IPI01011523   IPI01011672   IPI01011144   IPI00791960   IPI01010435   IPI01015742   IPI01015336   IPI01014576   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y2H1
IntAct (EBI)Q9Y2H1
FunCoupENSG00000211455
BioGRIDSTK38L
STRING (EMBL)STK38L
ZODIACSTK38L
Ontologies - Pathways
QuickGOQ9Y2H1
Ontology : AmiGOmagnesium ion binding  actin binding  protein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  protein phosphorylation  actin cytoskeleton  membrane  peptidyl-serine phosphorylation  intracellular signal transduction  regulation of cellular component organization  
Ontology : EGO-EBImagnesium ion binding  actin binding  protein serine/threonine kinase activity  protein binding  ATP binding  cytoplasm  protein phosphorylation  actin cytoskeleton  membrane  peptidyl-serine phosphorylation  intracellular signal transduction  regulation of cellular component organization  
NDEx NetworkSTK38L
Atlas of Cancer Signalling NetworkSTK38L
Wikipedia pathwaysSTK38L
Orthology - Evolution
OrthoDB23012
GeneTree (enSembl)ENSG00000211455
Phylogenetic Trees/Animal Genes : TreeFamSTK38L
HOVERGENQ9Y2H1
HOGENOMQ9Y2H1
Homologs : HomoloGeneSTK38L
Homology/Alignments : Family Browser (UCSC)STK38L
Gene fusions - Rearrangements
Fusion : MitelmanNAP1L1/STK38L [12q21.2/12p11.23]  [t(12;12)(p11;q21)]  
Fusion : MitelmanWNK1/STK38L [12p13.33/12p11.23]  [t(12;12)(p11;p13)]  
Fusion: TCGANAP1L1 12q21.2 STK38L 12p11.23 BRCA
Fusion: TCGAWNK1 12p13.33 STK38L 12p11.23 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTK38L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STK38L
dbVarSTK38L
ClinVarSTK38L
1000_GenomesSTK38L 
Exome Variant ServerSTK38L
ExAC (Exome Aggregation Consortium)STK38L (select the gene name)
Genetic variants : HAPMAP23012
Genomic Variants (DGV)STK38L [DGVbeta]
DECIPHER (Syndromes)12:27397078-27478890  ENSG00000211455
CONAN: Copy Number AnalysisSTK38L 
Mutations
ICGC Data PortalSTK38L 
TCGA Data PortalSTK38L 
Broad Tumor PortalSTK38L
OASIS PortalSTK38L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTK38L  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTK38L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STK38L
DgiDB (Drug Gene Interaction Database)STK38L
DoCM (Curated mutations)STK38L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STK38L (select a term)
intoGenSTK38L
Cancer3DSTK38L(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615836   
Orphanet
MedgenSTK38L
Genetic Testing Registry STK38L
NextProtQ9Y2H1 [Medical]
TSGene23012
GENETestsSTK38L
Huge Navigator STK38L [HugePedia]
snp3D : Map Gene to Disease23012
BioCentury BCIQSTK38L
ClinGenSTK38L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23012
Chemical/Pharm GKB GenePA38252
Clinical trialSTK38L
Miscellaneous
canSAR (ICR)STK38L (select the gene name)
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTK38L
EVEXSTK38L
GoPubMedSTK38L
iHOPSTK38L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:29:41 CET 2017

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