STOM (stomatin)

2015-02-01  

Identity

HGNC
LOCATION
9q33.2
LOCUSID
ALIAS
BND7,EPB7,EPB72
FUSION GENES

Other Information

Locus ID:

NCBI: 2040
MIM: 133090
HGNC: 3383
Ensembl: ENSG00000148175

Variants:

dbSNP: 2040
ClinVar: 2040
TCGA: ENSG00000148175
COSMIC: STOM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148175ENST00000286713P27105
ENSG00000148175ENST00000286713A0A024R882
ENSG00000148175ENST00000347359P27105
ENSG00000148175ENST00000538954F8VSL7

Expression (GTEx)

0
50
100
150
200
250
300
350
400
450
500

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Ion channel transportREACTOMER-HSA-983712
Stimuli-sensing channelsREACTOMER-HSA-2672351
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
180675072008Vesicles generated during storage of red cells are rich in the lipid raft marker stomatin.46
154718602004Stomatin modulates gating of acid-sensing ion channels.40
215018852012Stomatin-domain proteins.28
167665302006Characterization of the stomatin domain involved in homo-oligomerization and lipid raft association.22
121305002002Stomatin is a major lipid-raft component of platelet alpha granules.20
245334412014Simultaneous expression of flotillin-1, flotillin-2, stomatin and caveolin-1 in non-small cell lung cancer and soft tissue sarcomas.20
232198022013Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains.19
182670072008Slipins: ancient origin, duplication and diversification of the stomatin protein family.16
196960252009Stomatin-like protein-1 interacts with stomatin and is targeted to late endosomes.15
151211012004Eukaryotic and prokaryotic stomatins: the proteolytic link.13

Citation

Dessen P

STOM (stomatin)

Atlas Genet Cytogenet Oncol Haematol. 2015-02-01

Online version: http://atlasgeneticsoncology.org/gene/54975/stom