STOX1 (storkhead box 1)

2016-10-01  

Identity

HGNC
STOX1
LOCATION
10q22.1
LOCUSID
219736
ALIAS
C10orf24

Other Information

Locus ID:

NCBI: 219736
MIM: 609397
HGNC: 23508
Ensembl: ENSG00000165730

Variants:

dbSNP: 219736
ClinVar: 219736
TCGA: ENSG00000165730
COSMIC: STOX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000165730ENST00000298596Q6ZVD7
ENSG00000165730ENST00000399162Q6ZVD7
ENSG00000165730ENST00000399165Q6ZVD7
ENSG00000165730ENST00000399169Q6ZVD7
ENSG00000165730ENST00000642869A0A2R8Y5I4

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
204004612010The STOX1 genotype associated with pre-eclampsia leads to a reduction of trophoblast invasion by alpha-T-catenin upregulation.25
214907912011STOX1: Key player in trophoblast dysfunction underlying early onset preeclampsia with growth retardation.23
190795452008STOX1 overexpression in choriocarcinoma cells mimics transcriptional alterations observed in preeclamptic placentas.17
201106112010The pre-eclampsia gene STOX1 controls a conserved pathway in placenta and brain upregulated in late-onset Alzheimer's disease.15
172902742007Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample.13
172902742007Evaluation of STOX1 as a preeclampsia candidate gene in a population-wide sample.13
176171932007STOX1 gene in pre-eclampsia and intrauterine growth restriction.13
206438762010STOX2 but not STOX1 is differentially expressed in decidua from pre-eclamptic women: data from the Second Nord-Trondelag Health Study.12
207169642010Differential methylation of STOX1 in human placenta.12
267586112016Endothelial cell dysfunction and cardiac hypertrophy in the STOX1 model of preeclampsia.9

Citation

Dessen P

STOX1 (storkhead box 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56260/stox1