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STRADA (STE20 related adaptor alpha)

Identity

Alias (NCBI)LYK5
NY-BR-96
PMSE
STRAD
STRAD alpha
Stlk
HGNC (Hugo) STRADA
HGNC Alias symbNY-BR-96
LYK5
Stlk
STRAD
HGNC Alias nameSTE20-like pseudokinase
HGNC Previous nameSTE20-related kinase adaptor alpha
LocusID (NCBI) 92335
Atlas_Id 45584
Location 17q23.3  [Link to chromosome band 17q23]
Location_base_pair Starts at 63702832 and ends at 63741986 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
PARK2 (6q26) / STRADA (17q23.3)STARD3 (17q12) / STRADA (17q23.3)STRADA (17q23.3) / AGBL4 (1p33)
TANC2 (17q23.2) / STRADA (17q23.3)TMEM218 (11q24.2) / STRADA (17q23.3)PARK2 6q26 / STRADA 17q23.3
STARD3 17q12 / STRADA 17q23.3TANC2 17q23.2 / STRADA 17q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STRADA   30172
Cards
Entrez_Gene (NCBI)STRADA    STE20 related adaptor alpha
AliasesLYK5; NY-BR-96; PMSE; STRAD; 
STRAD; Stlk
GeneCards (Weizmann)STRADA
Ensembl hg19 (Hinxton)ENSG00000266173 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000266173 [Gene_View]  ENSG00000266173 [Sequence]  chr17:63702832-63741986 [Contig_View]  STRADA [Vega]
ICGC DataPortalENSG00000266173
TCGA cBioPortalSTRADA
AceView (NCBI)STRADA
Genatlas (Paris)STRADA
SOURCE (Princeton)STRADA
Genetics Home Reference (NIH)STRADA
Genomic and cartography
GoldenPath hg38 (UCSC)STRADA  -     chr17:63702832-63741986 -  17q23.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STRADA  -     17q23.3   [Description]    (hg19-Feb_2009)
GoldenPathSTRADA - 17q23.3 [CytoView hg19]  STRADA - 17q23.3 [CytoView hg38]
ImmunoBaseENSG00000266173
Genome Data Viewer NCBISTRADA [Mapview hg19]  
OMIM608626   611087   
Gene and transcription
Genbank (Entrez)AF308302 AK074771 AK075005 AK128173 AK293160
RefSeq transcript (Entrez)NM_001003786 NM_001003787 NM_001003788 NM_001165969 NM_001165970 NM_001363786 NM_001363787 NM_001363788 NM_001363789 NM_001363790 NM_001363791 NM_153335
Consensus coding sequences : CCDS (NCBI)STRADA
Gene ExpressionSTRADA [ NCBI-GEO ]   STRADA [ EBI - ARRAY_EXPRESS ]   STRADA [ SEEK ]   STRADA [ MEM ]
Gene Expression Viewer (FireBrowse)STRADA [ Firebrowse - Broad ]
GenevisibleExpression of STRADA in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92335
GTEX Portal (Tissue expression)STRADA
Human Protein AtlasENSG00000266173-STRADA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7RTN6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7RTN6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7RTN6
PhosPhoSitePlusQ7RTN6
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom_sf    Prot_kinase_dom   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Conserved Domain (NCBI)STRADA
PDB (RSDB)1UPK    2WTK    3GNI   
PDB Europe1UPK    2WTK    3GNI   
PDB (PDBSum)1UPK    2WTK    3GNI   
PDB (IMB)1UPK    2WTK    3GNI   
Structural Biology KnowledgeBase1UPK    2WTK    3GNI   
SCOP (Structural Classification of Proteins)1UPK    2WTK    3GNI   
CATH (Classification of proteins structures)1UPK    2WTK    3GNI   
SuperfamilyQ7RTN6
AlphaFold pdb e-kbQ7RTN6   
Human Protein Atlas [tissue]ENSG00000266173-STRADA [tissue]
HPRD14332
Protein Interaction databases
DIP (DOE-UCLA)Q7RTN6
IntAct (EBI)Q7RTN6
BioGRIDSTRADA
STRING (EMBL)STRADA
ZODIACSTRADA
Ontologies - Pathways
QuickGOQ7RTN6
Ontology : AmiGOprotein kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  protein phosphorylation  protein export from nucleus  cell cycle  kinase binding  protein kinase activator activity  activation of protein kinase activity  protein serine/threonine kinase activator activity  positive regulation of protein serine/threonine kinase activity  
Ontology : EGO-EBIprotein kinase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  protein phosphorylation  protein export from nucleus  cell cycle  kinase binding  protein kinase activator activity  activation of protein kinase activity  protein serine/threonine kinase activator activity  positive regulation of protein serine/threonine kinase activity  
Pathways : KEGGmTOR signaling pathway   
NDEx NetworkSTRADA
Atlas of Cancer Signalling NetworkSTRADA
Wikipedia pathwaysSTRADA
Orthology - Evolution
OrthoDB92335
GeneTree (enSembl)ENSG00000266173
Phylogenetic Trees/Animal Genes : TreeFamSTRADA
Homologs : HomoloGeneSTRADA
Homology/Alignments : Family Browser (UCSC)STRADA
Gene fusions - Rearrangements
Fusion : MitelmanPARK2/STRADA [6q26/17q23.3]  
Fusion : MitelmanSTARD3/STRADA [17q12/17q23.3]  
Fusion : MitelmanTANC2/STRADA [17q23.2/17q23.3]  
Fusion : QuiverSTRADA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTRADA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STRADA
dbVarSTRADA
ClinVarSTRADA
MonarchSTRADA
1000_GenomesSTRADA 
Exome Variant ServerSTRADA
GNOMAD BrowserENSG00000266173
Varsome BrowserSTRADA
ACMGSTRADA variants
VarityQ7RTN6
Genomic Variants (DGV)STRADA [DGVbeta]
DECIPHERSTRADA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTRADA 
Mutations
ICGC Data PortalSTRADA 
TCGA Data PortalSTRADA 
Broad Tumor PortalSTRADA
OASIS PortalSTRADA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTRADA  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTRADA
Mutations and Diseases : HGMDSTRADA
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTRADA
DgiDB (Drug Gene Interaction Database)STRADA
DoCM (Curated mutations)STRADA
CIViC (Clinical Interpretations of Variants in Cancer)STRADA
Cancer3DSTRADA
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608626    611087   
Orphanet
DisGeNETSTRADA
MedgenSTRADA
Genetic Testing Registry STRADA
NextProtQ7RTN6 [Medical]
GENETestsSTRADA
Target ValidationSTRADA
Huge Navigator STRADA [HugePedia]
ClinGenSTRADA
Clinical trials, drugs, therapy
MyCancerGenomeSTRADA
Protein Interactions : CTDSTRADA
Pharm GKB GenePA164726342
PharosQ7RTN6
Clinical trialSTRADA
Miscellaneous
canSAR (ICR)STRADA
HarmonizomeSTRADA
DataMed IndexSTRADA
Probes
Litterature
PubMed38 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTRADA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:33:40 CEST 2021

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