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STRADB (STE20-related kinase adaptor beta)

Identity

Alias_namesALS2CR2
amyotrophic lateral sclerosis 2 (juvenile) chromosome region
Alias_symbol (synonym)CALS-21
PAPK
ILPIPA
ILPIP
Other aliasPRO1038
HGNC (Hugo) STRADB
LocusID (NCBI) 55437
Atlas_Id 43116
Location 2q33.1  [Link to chromosome band 2q33]
Location_base_pair Starts at 201451669 and ends at 201480851 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
STRADB (2q33.1) / NOP58 (2q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STRADB   13205
Cards
Entrez_Gene (NCBI)STRADB  55437  STE20-related kinase adaptor beta
AliasesALS2CR2; CALS-21; ILPIP; ILPIPA; 
PAPK; PRO1038
GeneCards (Weizmann)STRADB
Ensembl hg19 (Hinxton)ENSG00000082146 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000082146 [Gene_View]  chr2:201451669-201480851 [Contig_View]  STRADB [Vega]
ICGC DataPortalENSG00000082146
TCGA cBioPortalSTRADB
AceView (NCBI)STRADB
Genatlas (Paris)STRADB
WikiGenes55437
SOURCE (Princeton)STRADB
Genetics Home Reference (NIH)STRADB
Genomic and cartography
GoldenPath hg38 (UCSC)STRADB  -     chr2:201451669-201480851 +  2q33.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STRADB  -     2q33.1   [Description]    (hg19-Feb_2009)
EnsemblSTRADB - 2q33.1 [CytoView hg19]  STRADB - 2q33.1 [CytoView hg38]
Mapping of homologs : NCBISTRADB [Mapview hg19]  STRADB [Mapview hg38]
OMIM607333   
Gene and transcription
Genbank (Entrez)AB038950 AF116618 AK024720 AK027637 AK290457
RefSeq transcript (Entrez)NM_001206864 NM_018571
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STRADB
Cluster EST : UnigeneHs.652338 [ NCBI ]
CGAP (NCI)Hs.652338
Alternative Splicing GalleryENSG00000082146
Gene ExpressionSTRADB [ NCBI-GEO ]   STRADB [ EBI - ARRAY_EXPRESS ]   STRADB [ SEEK ]   STRADB [ MEM ]
Gene Expression Viewer (FireBrowse)STRADB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55437
GTEX Portal (Tissue expression)STRADB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9C0K7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9C0K7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9C0K7
Splice isoforms : SwissVarQ9C0K7
PhosPhoSitePlusQ9C0K7
Domaine pattern : Prosite (Expaxy)PROTEIN_KINASE_DOM (PS50011)   
Domains : Interpro (EBI)Kinase-like_dom    Prot_kinase_dom   
Domain families : Pfam (Sanger)Pkinase (PF00069)   
Domain families : Pfam (NCBI)pfam00069   
Conserved Domain (NCBI)STRADB
DMDM Disease mutations55437
Blocks (Seattle)STRADB
SuperfamilyQ9C0K7
Human Protein AtlasENSG00000082146
Peptide AtlasQ9C0K7
HPRD09546
IPIIPI00032099   IPI00657901   IPI00658041   IPI01015995   IPI00924668   IPI00924904   IPI00925137   
Protein Interaction databases
DIP (DOE-UCLA)Q9C0K7
IntAct (EBI)Q9C0K7
FunCoupENSG00000082146
BioGRIDSTRADB
STRING (EMBL)STRADB
ZODIACSTRADB
Ontologies - Pathways
QuickGOQ9C0K7
Ontology : AmiGOcell morphogenesis  protein kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  cytosol  protein phosphorylation  protein export from nucleus  cell cycle arrest  aggresome  activation of protein kinase activity  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
Ontology : EGO-EBIcell morphogenesis  protein kinase activity  protein binding  ATP binding  nucleus  cytoplasm  cytosol  cytosol  protein phosphorylation  protein export from nucleus  cell cycle arrest  aggresome  activation of protein kinase activity  negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  
NDEx NetworkSTRADB
Atlas of Cancer Signalling NetworkSTRADB
Wikipedia pathwaysSTRADB
Orthology - Evolution
OrthoDB55437
GeneTree (enSembl)ENSG00000082146
Phylogenetic Trees/Animal Genes : TreeFamSTRADB
HOVERGENQ9C0K7
HOGENOMQ9C0K7
Homologs : HomoloGeneSTRADB
Homology/Alignments : Family Browser (UCSC)STRADB
Gene fusions - Rearrangements
Fusion : MitelmanSTRADB/NOP58 [2q33.1/2q33.1]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTRADB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STRADB
dbVarSTRADB
ClinVarSTRADB
1000_GenomesSTRADB 
Exome Variant ServerSTRADB
ExAC (Exome Aggregation Consortium)STRADB (select the gene name)
Genetic variants : HAPMAP55437
Genomic Variants (DGV)STRADB [DGVbeta]
DECIPHERSTRADB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTRADB 
Mutations
ICGC Data PortalSTRADB 
TCGA Data PortalSTRADB 
Broad Tumor PortalSTRADB
OASIS PortalSTRADB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTRADB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTRADB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STRADB
DgiDB (Drug Gene Interaction Database)STRADB
DoCM (Curated mutations)STRADB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STRADB (select a term)
intoGenSTRADB
Cancer3DSTRADB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607333   
Orphanet
MedgenSTRADB
Genetic Testing Registry STRADB
NextProtQ9C0K7 [Medical]
TSGene55437
GENETestsSTRADB
Target ValidationSTRADB
Huge Navigator STRADB [HugePedia]
snp3D : Map Gene to Disease55437
BioCentury BCIQSTRADB
ClinGenSTRADB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55437
Chemical/Pharm GKB GenePA24743
Clinical trialSTRADB
Miscellaneous
canSAR (ICR)STRADB (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTRADB
EVEXSTRADB
GoPubMedSTRADB
iHOPSTRADB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:33:35 CEST 2017

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