Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

STRAP (serine/threonine kinase receptor associated protein)

Identity

Other namesMAWD
PT-WD
UNRIP
HGNC (Hugo) STRAP
LocusID (NCBI) 11171
Atlas_Id 42445
Location 12p12.3
Location_base_pair Starts at 16035288 and ends at 16056410 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
HERC3 (4q22.1) / STRAP (12p12.3)PFKP (10p15.2) / STRAP (12p12.3)RNF19A (8q22.2) / STRAP (12p12.3)
STRAP (12p12.3) / IMMT (2p11.2)STRAP (12p12.3) / STRAP (12p12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STRAP   30796
Cards
Entrez_Gene (NCBI)STRAP  11171  serine/threonine kinase receptor associated protein
AliasesMAWD; PT-WD; UNRIP
GeneCards (Weizmann)STRAP
Ensembl hg19 (Hinxton)ENSG00000023734 [Gene_View]  chr12:16035288-16056410 [Contig_View]  STRAP [Vega]
Ensembl hg38 (Hinxton)ENSG00000023734 [Gene_View]  chr12:16035288-16056410 [Contig_View]  STRAP [Vega]
ICGC DataPortalENSG00000023734
TCGA cBioPortalSTRAP
AceView (NCBI)STRAP
Genatlas (Paris)STRAP
WikiGenes11171
SOURCE (Princeton)STRAP
Genomic and cartography
GoldenPath hg19 (UCSC)STRAP  -     chr12:16035288-16056410 +  12p12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STRAP  -     12p12.3   [Description]    (hg38-Dec_2013)
EnsemblSTRAP - 12p12.3 [CytoView hg19]  STRAP - 12p12.3 [CytoView hg38]
Mapping of homologs : NCBISTRAP [Mapview hg19]  STRAP [Mapview hg38]
OMIM605986   
Gene and transcription
Genbank (Entrez)AB024327 AF161496 AJ010025 AK297942 AK312295
RefSeq transcript (Entrez)NM_007178
RefSeq genomic (Entrez)NC_000012 NC_018923 NT_009714 NW_004929383
Consensus coding sequences : CCDS (NCBI)STRAP
Cluster EST : UnigeneHs.743971 [ NCBI ]
CGAP (NCI)Hs.743971
Alternative Splicing GalleryENSG00000023734
Gene ExpressionSTRAP [ NCBI-GEO ]   STRAP [ EBI - ARRAY_EXPRESS ]   STRAP [ SEEK ]   STRAP [ MEM ]
Gene Expression Viewer (FireBrowse)STRAP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11171
GTEX Portal (Tissue expression)STRAP
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3F4 (Uniprot)
NextProtQ9Y3F4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3F4
Splice isoforms : SwissVarQ9Y3F4 (Swissvar)
PhosPhoSitePlusQ9Y3F4
Domaine pattern : Prosite (Expaxy)WD_REPEATS_1 (PS00678)    WD_REPEATS_2 (PS50082)    WD_REPEATS_REGION (PS50294)   
Domains : Interpro (EBI)G-protein_beta_WD-40_rep    WD40/YVTN_repeat-like_dom    WD40_repeat    WD40_repeat_CS    WD40_repeat_dom   
Domain families : Pfam (Sanger)WD40 (PF00400)   
Domain families : Pfam (NCBI)pfam00400   
Domain families : Smart (EMBL)WD40 (SM00320)  
DMDM Disease mutations11171
Blocks (Seattle)STRAP
SuperfamilyQ9Y3F4
Human Protein AtlasENSG00000023734
Peptide AtlasQ9Y3F4
HPRD05816
IPIIPI00941907   IPI01015342   IPI01013159   IPI00294536   IPI01011918   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3F4
IntAct (EBI)Q9Y3F4
FunCoupENSG00000023734
BioGRIDSTRAP
STRING (EMBL)STRAP
ZODIACSTRAP
Ontologies - Pathways
QuickGOQ9Y3F4
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  spliceosomal snRNP assembly  receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytosol  negative regulation of epithelial cell migration  negative regulation of epithelial to mesenchymal transition  maintenance of gastrointestinal epithelium  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  SMN complex  SMN-Sm protein complex  poly(A) RNA binding  negative regulation of epithelial cell proliferation  negative regulation of pathway-restricted SMAD protein phosphorylation  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  spliceosomal snRNP assembly  receptor binding  protein binding  nucleus  cytoplasm  cytosol  cytosol  negative regulation of epithelial cell migration  negative regulation of epithelial to mesenchymal transition  maintenance of gastrointestinal epithelium  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  SMN complex  SMN-Sm protein complex  poly(A) RNA binding  negative regulation of epithelial cell proliferation  negative regulation of pathway-restricted SMAD protein phosphorylation  
Pathways : KEGGRNA transport   
NDEx Network
Atlas of Cancer Signalling NetworkSTRAP
Wikipedia pathwaysSTRAP
Orthology - Evolution
OrthoDB11171
GeneTree (enSembl)ENSG00000023734
Phylogenetic Trees/Animal Genes : TreeFamSTRAP
Homologs : HomoloGeneSTRAP
Homology/Alignments : Family Browser (UCSC)STRAP
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSTRAP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STRAP
dbVarSTRAP
ClinVarSTRAP
1000_GenomesSTRAP 
Exome Variant ServerSTRAP
ExAC (Exome Aggregation Consortium)STRAP (select the gene name)
Genetic variants : HAPMAP11171
Genomic Variants (DGV)STRAP [DGVbeta]
Mutations
ICGC Data PortalSTRAP 
TCGA Data PortalSTRAP 
Broad Tumor PortalSTRAP
OASIS PortalSTRAP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTRAP 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STRAP
DgiDB (Drug Gene Interaction Database)STRAP
DoCM (Curated mutations)STRAP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STRAP (select a term)
intoGenSTRAP
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:16035288-16056410  ENSG00000023734
CONAN: Copy Number AnalysisSTRAP 
Mutations and Diseases : HGMDSTRAP
OMIM605986   
MedgenSTRAP
Genetic Testing Registry STRAP
NextProtQ9Y3F4 [Medical]
TSGene11171
GENETestsSTRAP
Huge Navigator STRAP [HugePedia]
snp3D : Map Gene to Disease11171
BioCentury BCIQSTRAP
ClinGenSTRAP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11171
Chemical/Pharm GKB GenePA134867032
Clinical trialSTRAP
Miscellaneous
canSAR (ICR)STRAP (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTRAP
EVEXSTRAP
GoPubMedSTRAP
iHOPSTRAP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat May 28 11:23:20 CEST 2016

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.