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STT3B (STT3B, catalytic subunit of the oligosaccharyltransferase complex)

Identity

Alias_namesSTT3
Alias_symbol (synonym)SIMP
FLJ90106
STT3-B
Other aliasCDG1X
HGNC (Hugo) STT3B
LocusID (NCBI) 201595
Atlas_Id 53359
Location 3p23  [Link to chromosome band 3p23]
Location_base_pair Starts at 31532501 and ends at 31637622 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
GPD1L (3p22.3) / STT3B (3p23)GPD1L 3p22.3 / STT3B 3p23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STT3B   30611
Cards
Entrez_Gene (NCBI)STT3B  201595  STT3B, catalytic subunit of the oligosaccharyltransferase complex
AliasesCDG1X; SIMP; STT3-B
GeneCards (Weizmann)STT3B
Ensembl hg19 (Hinxton)ENSG00000163527 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163527 [Gene_View]  chr3:31532501-31637622 [Contig_View]  STT3B [Vega]
ICGC DataPortalENSG00000163527
TCGA cBioPortalSTT3B
AceView (NCBI)STT3B
Genatlas (Paris)STT3B
WikiGenes201595
SOURCE (Princeton)STT3B
Genetics Home Reference (NIH)STT3B
Genomic and cartography
GoldenPath hg38 (UCSC)STT3B  -     chr3:31532501-31637622 +  3p23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STT3B  -     3p23   [Description]    (hg19-Feb_2009)
EnsemblSTT3B - 3p23 [CytoView hg19]  STT3B - 3p23 [CytoView hg38]
Mapping of homologs : NCBISTT3B [Mapview hg19]  STT3B [Mapview hg38]
OMIM608605   615597   
Gene and transcription
Genbank (Entrez)AI914841 AK027789 AK074587 AK075380 AK311488
RefSeq transcript (Entrez)NM_178862
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STT3B
Cluster EST : UnigeneHs.475812 [ NCBI ]
CGAP (NCI)Hs.475812
Alternative Splicing GalleryENSG00000163527
Gene ExpressionSTT3B [ NCBI-GEO ]   STT3B [ EBI - ARRAY_EXPRESS ]   STT3B [ SEEK ]   STT3B [ MEM ]
Gene Expression Viewer (FireBrowse)STT3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201595
GTEX Portal (Tissue expression)STT3B
Human Protein AtlasENSG00000163527-STT3B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCJ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCJ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCJ2
Splice isoforms : SwissVarQ8TCJ2
Catalytic activity : Enzyme2.4.99.18 [ Enzyme-Expasy ]   2.4.99.182.4.99.18 [ IntEnz-EBI ]   2.4.99.18 [ BRENDA ]   2.4.99.18 [ KEGG ]   
PhosPhoSitePlusQ8TCJ2
Domains : Interpro (EBI)Oligo_trans_STT3   
Domain families : Pfam (Sanger)STT3 (PF02516)   
Domain families : Pfam (NCBI)pfam02516   
Conserved Domain (NCBI)STT3B
DMDM Disease mutations201595
Blocks (Seattle)STT3B
SuperfamilyQ8TCJ2
Human Protein Atlas [tissue]ENSG00000163527-STT3B [tissue]
Peptide AtlasQ8TCJ2
HPRD12268
IPIIPI00152377   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCJ2
IntAct (EBI)Q8TCJ2
FunCoupENSG00000163527
BioGRIDSTT3B
STRING (EMBL)STT3B
ZODIACSTT3B
Ontologies - Pathways
QuickGOQ8TCJ2
Ontology : AmiGOdolichyl-diphosphooligosaccharide-protein glycotransferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  endoplasmic reticulum  glycoprotein catabolic process  response to unfolded protein  oligosaccharyltransferase complex  oligosaccharyltransferase complex  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  ubiquitin-dependent ERAD pathway  co-translational protein modification  post-translational protein modification  metal ion binding  
Ontology : EGO-EBIdolichyl-diphosphooligosaccharide-protein glycotransferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  endoplasmic reticulum  glycoprotein catabolic process  response to unfolded protein  oligosaccharyltransferase complex  oligosaccharyltransferase complex  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  ubiquitin-dependent ERAD pathway  co-translational protein modification  post-translational protein modification  metal ion binding  
Pathways : KEGGN-Glycan biosynthesis    Protein processing in endoplasmic reticulum   
NDEx NetworkSTT3B
Atlas of Cancer Signalling NetworkSTT3B
Wikipedia pathwaysSTT3B
Orthology - Evolution
OrthoDB201595
GeneTree (enSembl)ENSG00000163527
Phylogenetic Trees/Animal Genes : TreeFamSTT3B
HOVERGENQ8TCJ2
HOGENOMQ8TCJ2
Homologs : HomoloGeneSTT3B
Homology/Alignments : Family Browser (UCSC)STT3B
Gene fusions - Rearrangements
Fusion : MitelmanGPD1L/STT3B [3p22.3/3p23]  [t(3;3)(p22;p23)]  
Fusion: TCGA_MDACCGPD1L 3p22.3 STT3B 3p23 BLCA
Tumor Fusion PortalSTT3B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTT3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STT3B
dbVarSTT3B
ClinVarSTT3B
1000_GenomesSTT3B 
Exome Variant ServerSTT3B
ExAC (Exome Aggregation Consortium)ENSG00000163527
GNOMAD BrowserENSG00000163527
Genetic variants : HAPMAP201595
Genomic Variants (DGV)STT3B [DGVbeta]
DECIPHERSTT3B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTT3B 
Mutations
ICGC Data PortalSTT3B 
TCGA Data PortalSTT3B 
Broad Tumor PortalSTT3B
OASIS PortalSTT3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTT3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTT3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STT3B
DgiDB (Drug Gene Interaction Database)STT3B
DoCM (Curated mutations)STT3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STT3B (select a term)
intoGenSTT3B
Cancer3DSTT3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608605    615597   
Orphanet22501   
DisGeNETSTT3B
MedgenSTT3B
Genetic Testing Registry STT3B
NextProtQ8TCJ2 [Medical]
TSGene201595
GENETestsSTT3B
Target ValidationSTT3B
Huge Navigator STT3B [HugePedia]
snp3D : Map Gene to Disease201595
BioCentury BCIQSTT3B
ClinGenSTT3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201595
Chemical/Pharm GKB GenePA143485625
Clinical trialSTT3B
Miscellaneous
canSAR (ICR)STT3B (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTT3B
EVEXSTT3B
GoPubMedSTT3B
iHOPSTT3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:37:06 CET 2017

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