STUB1 (STIP1 homology and U-box containing protein 1)

Identity

Other names	CHIP
	HSPABP2
	NY-CO-7
	SDCCAG7
	UBOX1
HGNC	STUB1
Location	16p13.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	STUB1   11427
Entrez_Gene	STUB1  10273  STIP1 homology and U-box containing protein 1
	Cards
GeneCards	STUB1
Ensembl	STUB1 [Search_View]   ENSG00000103266 [Gene_View]
Genatlas	STUB1
GeneLynx	STUB1
eGenome	STUB1
euGene	10273
	Genomic and cartography
GoldenPath	STUB1  -  16p13.3   chr16:670116-672769 +  16p13.3   [Description]    (hg18-March_2006)
Ensembl	STUB1 - 16p13.3 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	STUB1
	Gene and transcription
Genbank	AF039689 [ ENTREZ ]
Genbank	AF129085 [ ENTREZ ]
Genbank	AF217968 [ ENTREZ ]
Genbank	AF432221 [ ENTREZ ]
Genbank	BC007545 [ ENTREZ ]
RefSeq	NM_005861 [ SRS ]    NM_005861 [ ENTREZ ]
RefSeq	AC_000059 [ SRS ]    AC_000059 [ ENTREZ ]
RefSeq	AC_000148 [ SRS ]    AC_000148 [ ENTREZ ]
RefSeq	NC_000016 [ SRS ]    NC_000016 [ ENTREZ ]
RefSeq	NT_037887 [ SRS ]    NT_037887 [ ENTREZ ]
RefSeq	NW_001838339 [ SRS ]    NW_001838339 [ ENTREZ ]
RefSeq	NW_926018 [ SRS ]    NW_926018 [ ENTREZ ]
AceView	STUB1 AceView - NCBI
Unigene	Hs.592081 [ SRS ]    Hs.592081 [ NCBI ]     HS592081 [ spliceNest ]
Fast-db	684 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	Q9UNE7 [ SRS]    Q9UNE7 [ EXPASY ]     Q9UNE7 [ INTERPRO ]     Q9UNE7 [ UNIPROT ]
Prosite	PS50005 TPR [ SRS ]    PS50005 TPR [ Expasy ]
Prosite	PS50293 TPR_REGION [ SRS ]    PS50293 TPR_REGION [ Expasy ]
Interpro	IPR001440 TPR-1 [ SRS ]    IPR001440 TPR-1 [ EBI ]
Interpro	IPR011990 TPR-like_helical [ SRS ]    IPR011990 TPR-like_helical [ EBI ]
Interpro	IPR013026 TPR_region [ SRS ]    IPR013026 TPR_region [ EBI ]
Interpro	IPR003613 Ubox [ SRS ]    IPR003613 Ubox [ EBI ]
Interpro	IPR013083 Znf_RING/FYVE/PHD [ SRS ]    IPR013083 Znf_RING/FYVE/PHD [ EBI ]
CluSTr	Q9UNE7
Pfam	PF00515 TPR_1 [ SRS ]    PF00515 TPR_1 [ Sanger ]    pfam00515 [ NCBI-CDD ]
Pfam	PF04564 U-box [ SRS ]    PF04564 U-box [ Sanger ]    pfam04564 [ NCBI-CDD ]
Smart	SM00028 TPR [EMBL]
Smart	SM00504 Ubox [EMBL]
Blocks	Q9UNE7
HPRD	06232
	Protein Interaction databases
DIP	Q9UNE7
IntAct	Q9UNE7
	Polymorphism : SNP, mutations, diseases
OMIM	607207    [ map ]
GENECLINICS	607207
SNP	STUB1 [dbSNP-NCBI]
SNP	NM_005861 [SNP-NCI]
SNP	STUB1 [GeneSNPs - Utah]  STUB1] [HGBASE - SRS]
HAPMAP	STUB1 [HAPMAP]
COSMIC	STUB1 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	STUB1
	General knowledge
Family Browser	STUB1 [UCSC Family Browser]
SOURCE	NM_005861
SMD	Hs.592081
SAGE	Hs.592081
Enzyme	6.3.2.- [ Enzyme-Expasy ]   6.3.2.- [ Enzyme-SRS ]   6.3.2.- [ IntEnz-EBI ]   6.3.2.- [ BRENDA ]   6.3.2.- [ KEGG ]   6.3.2.- [ WIT ]
GO	ubiquitin ligase complex [Amigo]  ubiquitin ligase complex
GO	protein polyubiquitination [Amigo]  protein polyubiquitination
GO	ubiquitin-protein ligase activity [Amigo]  ubiquitin-protein ligase activity
GO	cytoplasm [Amigo]  cytoplasm
GO	protein folding [Amigo]  protein folding
GO	Hsp90 protein inhibitor activity [Amigo]  Hsp90 protein inhibitor activity
GO	ligase activity [Amigo]  ligase activity
GO	Hsp70/Hsc70 protein inhibitor activity [Amigo]  Hsp70/Hsc70 protein inhibitor activity
GO	Hsp70 protein binding [Amigo]  Hsp70 protein binding
GO	Hsp70 protein binding [Amigo]  Hsp70 protein binding
GO	ubiquitin-dependent SMAD protein catabolic process [Amigo]  ubiquitin-dependent SMAD protein catabolic process
GO	protein binding, bridging [Amigo]  protein binding, bridging
GO	TPR domain binding [Amigo]  TPR domain binding
GO	ubiquitin conjugating enzyme complex [Amigo]  ubiquitin conjugating enzyme complex
GO	positive regulation of protein ubiquitination [Amigo]  positive regulation of protein ubiquitination
GO	regulation of glucocorticoid metabolic process [Amigo]  regulation of glucocorticoid metabolic process
GO	positive regulation of proteasomal ubiquitin-dependent protein catabolic process [Amigo]  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO	protein homodimerization activity [Amigo]  protein homodimerization activity
GO	SMAD binding [Amigo]  SMAD binding
GO	protein maturation [Amigo]  protein maturation
GO	Hsp90 protein binding [Amigo]  Hsp90 protein binding
GO	Hsp90 protein binding [Amigo]  Hsp90 protein binding
PubGene	STUB1
TreeFam	STUB1
CTD	10273 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	STUB1 Related clones (RZPD - Berlin)
	PubMed
PubMed	48 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 18:24:27 2008