Atlas of Genetics and Cytogenetics in Oncology and Haematology


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STX11 (syntaxin 11)

Identity

Other aliasFHL4
HLH4
HPLH4
HGNC (Hugo) STX11
LocusID (NCBI) 8676
Atlas_Id 55638
Location 6q24.2  [Link to chromosome band 6q24]
Location_base_pair Starts at 144150517 and ends at 144191939 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
RPL3 (22q13.1) / STX11 (6q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STX11   11429
LRG (Locus Reference Genomic)LRG_113
Cards
Entrez_Gene (NCBI)STX11  8676  syntaxin 11
AliasesFHL4; HLH4; HPLH4
GeneCards (Weizmann)STX11
Ensembl hg19 (Hinxton)ENSG00000135604 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000135604 [Gene_View]  ENSG00000135604 [Sequence]  chr6:144150517-144191939 [Contig_View]  STX11 [Vega]
ICGC DataPortalENSG00000135604
TCGA cBioPortalSTX11
AceView (NCBI)STX11
Genatlas (Paris)STX11
WikiGenes8676
SOURCE (Princeton)STX11
Genetics Home Reference (NIH)STX11
Genomic and cartography
GoldenPath hg38 (UCSC)STX11  -     chr6:144150517-144191939 +  6q24.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STX11  -     6q24.2   [Description]    (hg19-Feb_2009)
EnsemblSTX11 - 6q24.2 [CytoView hg19]  STX11 - 6q24.2 [CytoView hg38]
Mapping of homologs : NCBISTX11 [Mapview hg19]  STX11 [Mapview hg38]
OMIM603552   605014   
Gene and transcription
Genbank (Entrez)AF038898 AF044309 AF071504 AI791689 AJ012501
RefSeq transcript (Entrez)NM_003764
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STX11
Cluster EST : UnigeneHs.118958 [ NCBI ]
CGAP (NCI)Hs.118958
Alternative Splicing GalleryENSG00000135604
Gene ExpressionSTX11 [ NCBI-GEO ]   STX11 [ EBI - ARRAY_EXPRESS ]   STX11 [ SEEK ]   STX11 [ MEM ]
Gene Expression Viewer (FireBrowse)STX11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8676
GTEX Portal (Tissue expression)STX11
Human Protein AtlasENSG00000135604-STX11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75558   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75558  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75558
Splice isoforms : SwissVarO75558
PhosPhoSitePlusO75558
Domaine pattern : Prosite (Expaxy)SYNTAXIN (PS00914)    T_SNARE (PS50192)   
Domains : Interpro (EBI)SNARE    STX11    Syntaxin/epimorphin_CS    Syntaxin_N    T_SNARE_dom   
Domain families : Pfam (Sanger)Syntaxin (PF00804)   
Domain families : Pfam (NCBI)pfam00804   
Domain families : Smart (EMBL)SynN (SM00503)  t_SNARE (SM00397)  
Conserved Domain (NCBI)STX11
DMDM Disease mutations8676
Blocks (Seattle)STX11
SuperfamilyO75558
Human Protein Atlas [tissue]ENSG00000135604-STX11 [tissue]
Peptide AtlasO75558
HPRD09231
IPIIPI00026128   
Protein Interaction databases
DIP (DOE-UCLA)O75558
IntAct (EBI)O75558
FunCoupENSG00000135604
BioGRIDSTX11
STRING (EMBL)STX11
ZODIACSTX11
Ontologies - Pathways
QuickGOO75558
Ontology : AmiGOSNARE binding  SNAP receptor activity  protein binding  Golgi apparatus  plasma membrane  intracellular protein transport  exocytosis  vesicle fusion  synaptic vesicle  endomembrane system  integral component of membrane  SNARE complex  synaptic vesicle fusion to presynaptic active zone membrane  presynaptic membrane  vesicle docking  presynaptic active zone membrane  membrane fusion  
Ontology : EGO-EBISNARE binding  SNAP receptor activity  protein binding  Golgi apparatus  plasma membrane  intracellular protein transport  exocytosis  vesicle fusion  synaptic vesicle  endomembrane system  integral component of membrane  SNARE complex  synaptic vesicle fusion to presynaptic active zone membrane  presynaptic membrane  vesicle docking  presynaptic active zone membrane  membrane fusion  
Pathways : KEGGSNARE interactions in vesicular transport   
NDEx NetworkSTX11
Atlas of Cancer Signalling NetworkSTX11
Wikipedia pathwaysSTX11
Orthology - Evolution
OrthoDB8676
GeneTree (enSembl)ENSG00000135604
Phylogenetic Trees/Animal Genes : TreeFamSTX11
HOVERGENO75558
HOGENOMO75558
Homologs : HomoloGeneSTX11
Homology/Alignments : Family Browser (UCSC)STX11
Gene fusions - Rearrangements
Fusion : QuiverSTX11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTX11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STX11
dbVarSTX11
ClinVarSTX11
1000_GenomesSTX11 
Exome Variant ServerSTX11
ExAC (Exome Aggregation Consortium)ENSG00000135604
GNOMAD BrowserENSG00000135604
Varsome BrowserSTX11
Genetic variants : HAPMAP8676
Genomic Variants (DGV)STX11 [DGVbeta]
DECIPHERSTX11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTX11 
Mutations
ICGC Data PortalSTX11 
TCGA Data PortalSTX11 
Broad Tumor PortalSTX11
OASIS PortalSTX11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTX11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTX11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)**PUBLIC** CCHMC Molecular Genetics Laboratory Mutation Database
BioMutasearch STX11
DgiDB (Drug Gene Interaction Database)STX11
DoCM (Curated mutations)STX11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STX11 (select a term)
intoGenSTX11
Cancer3DSTX11(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603552    605014   
Orphanet282   
DisGeNETSTX11
MedgenSTX11
Genetic Testing Registry STX11
NextProtO75558 [Medical]
TSGene8676
GENETestsSTX11
Target ValidationSTX11
Huge Navigator STX11 [HugePedia]
snp3D : Map Gene to Disease8676
BioCentury BCIQSTX11
ClinGenSTX11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8676
Chemical/Pharm GKB GenePA36229
Clinical trialSTX11
Miscellaneous
canSAR (ICR)STX11 (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTX11
EVEXSTX11
GoPubMedSTX11
iHOPSTX11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:42:47 CET 2018

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