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STX12 (syntaxin 12)

Identity

Alias_symbol (synonym)STX13
STX14
Other alias
HGNC (Hugo) STX12
LocusID (NCBI) 23673
Atlas_Id 56566
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 27773183 and ends at 27824452 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EIF2S1 (14q23.3) / STX12 (1p35.3)PHF6 (Xq26.2) / STX12 (1p35.3)SNED1 (2q37.3) / STX12 (1p35.3)
STX12 (1p35.3) / JARID2 (6p22.3)STX12 (1p35.3) / TMEM222 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STX12   11430
Cards
Entrez_Gene (NCBI)STX12  23673  syntaxin 12
AliasesSTX13; STX14
GeneCards (Weizmann)STX12
Ensembl hg19 (Hinxton)ENSG00000117758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117758 [Gene_View]  chr1:27773183-27824452 [Contig_View]  STX12 [Vega]
ICGC DataPortalENSG00000117758
TCGA cBioPortalSTX12
AceView (NCBI)STX12
Genatlas (Paris)STX12
WikiGenes23673
SOURCE (Princeton)STX12
Genetics Home Reference (NIH)STX12
Genomic and cartography
GoldenPath hg38 (UCSC)STX12  -     chr1:27773183-27824452 +  1p35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STX12  -     1p35.3   [Description]    (hg19-Feb_2009)
EnsemblSTX12 - 1p35.3 [CytoView hg19]  STX12 - 1p35.3 [CytoView hg38]
Mapping of homologs : NCBISTX12 [Mapview hg19]  STX12 [Mapview hg38]
OMIM606892   
Gene and transcription
Genbank (Entrez)AF070635 AF123769 AK095898 AK297585 AK299982
RefSeq transcript (Entrez)NM_177424
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STX12
Cluster EST : UnigeneHs.523855 [ NCBI ]
CGAP (NCI)Hs.523855
Alternative Splicing GalleryENSG00000117758
Gene ExpressionSTX12 [ NCBI-GEO ]   STX12 [ EBI - ARRAY_EXPRESS ]   STX12 [ SEEK ]   STX12 [ MEM ]
Gene Expression Viewer (FireBrowse)STX12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23673
GTEX Portal (Tissue expression)STX12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y82   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y82  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y82
Splice isoforms : SwissVarQ86Y82
PhosPhoSitePlusQ86Y82
Domaine pattern : Prosite (Expaxy)SYNTAXIN (PS00914)    T_SNARE (PS50192)   
Domains : Interpro (EBI)SNARE    Syntaxin/epimorphin_CS    Syntaxin_N    T_SNARE_dom   
Domain families : Pfam (Sanger)SNARE (PF05739)   
Domain families : Pfam (NCBI)pfam05739   
Domain families : Smart (EMBL)SynN (SM00503)  t_SNARE (SM00397)  
Conserved Domain (NCBI)STX12
DMDM Disease mutations23673
Blocks (Seattle)STX12
PDB (SRS)2DNX   
PDB (PDBSum)2DNX   
PDB (IMB)2DNX   
PDB (RSDB)2DNX   
Structural Biology KnowledgeBase2DNX   
SCOP (Structural Classification of Proteins)2DNX   
CATH (Classification of proteins structures)2DNX   
SuperfamilyQ86Y82
Human Protein AtlasENSG00000117758
Peptide AtlasQ86Y82
HPRD06059
IPIIPI00329332   IPI00513853   
Protein Interaction databases
DIP (DOE-UCLA)Q86Y82
IntAct (EBI)Q86Y82
FunCoupENSG00000117758
BioGRIDSTX12
STRING (EMBL)STX12
ZODIACSTX12
Ontologies - Pathways
QuickGOQ86Y82
Ontology : AmiGOautophagosome assembly  Golgi membrane  SNARE binding  pre-autophagosomal structure  SNAP receptor activity  protein binding  intracellular protein transport  vesicle fusion  endosome membrane  endomembrane system  integral component of membrane  BLOC-1 complex  SNARE complex  vesicle  cholesterol efflux  membrane raft  phagocytic vesicle  vesicle docking  protein stabilization  extracellular exosome  
Ontology : EGO-EBIautophagosome assembly  Golgi membrane  SNARE binding  pre-autophagosomal structure  SNAP receptor activity  protein binding  intracellular protein transport  vesicle fusion  endosome membrane  endomembrane system  integral component of membrane  BLOC-1 complex  SNARE complex  vesicle  cholesterol efflux  membrane raft  phagocytic vesicle  vesicle docking  protein stabilization  extracellular exosome  
Pathways : KEGGPhagosome   
NDEx NetworkSTX12
Atlas of Cancer Signalling NetworkSTX12
Wikipedia pathwaysSTX12
Orthology - Evolution
OrthoDB23673
GeneTree (enSembl)ENSG00000117758
Phylogenetic Trees/Animal Genes : TreeFamSTX12
HOVERGENQ86Y82
HOGENOMQ86Y82
Homologs : HomoloGeneSTX12
Homology/Alignments : Family Browser (UCSC)STX12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTX12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STX12
dbVarSTX12
ClinVarSTX12
1000_GenomesSTX12 
Exome Variant ServerSTX12
ExAC (Exome Aggregation Consortium)STX12 (select the gene name)
Genetic variants : HAPMAP23673
Genomic Variants (DGV)STX12 [DGVbeta]
DECIPHERSTX12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTX12 
Mutations
ICGC Data PortalSTX12 
TCGA Data PortalSTX12 
Broad Tumor PortalSTX12
OASIS PortalSTX12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTX12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTX12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STX12
DgiDB (Drug Gene Interaction Database)STX12
DoCM (Curated mutations)STX12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STX12 (select a term)
intoGenSTX12
Cancer3DSTX12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606892   
Orphanet
MedgenSTX12
Genetic Testing Registry STX12
NextProtQ86Y82 [Medical]
TSGene23673
GENETestsSTX12
Target ValidationSTX12
Huge Navigator STX12 [HugePedia]
snp3D : Map Gene to Disease23673
BioCentury BCIQSTX12
ClinGenSTX12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23673
Chemical/Pharm GKB GenePA36230
Clinical trialSTX12
Miscellaneous
canSAR (ICR)STX12 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTX12
EVEXSTX12
GoPubMedSTX12
iHOPSTX12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:08:53 CEST 2017

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