Atlas of Genetics and Cytogenetics in Oncology and Haematology


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STX12 (syntaxin 12)

Identity

Alias (NCBI)STX13
STX14
HGNC (Hugo) STX12
HGNC Alias symbSTX13
STX14
LocusID (NCBI) 23673
Atlas_Id 56566
Location 1p35.3  [Link to chromosome band 1p35]
Location_base_pair Starts at 27773219 and ends at 27824443 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EIF2S1 (14q23.3) / STX12 (1p35.3)PHF6 (Xq26.2) / STX12 (1p35.3)SNED1 (2q37.3) / STX12 (1p35.3)
STX12 (1p35.3) / JARID2 (6p22.3)STX12 (1p35.3) / TMEM222 (1p36.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)STX12   11430
Cards
Entrez_Gene (NCBI)STX12    syntaxin 12
AliasesSTX13; STX14
GeneCards (Weizmann)STX12
Ensembl hg19 (Hinxton)ENSG00000117758 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117758 [Gene_View]  ENSG00000117758 [Sequence]  chr1:27773219-27824443 [Contig_View]  STX12 [Vega]
ICGC DataPortalENSG00000117758
TCGA cBioPortalSTX12
AceView (NCBI)STX12
Genatlas (Paris)STX12
SOURCE (Princeton)STX12
Genetics Home Reference (NIH)STX12
Genomic and cartography
GoldenPath hg38 (UCSC)STX12  -     chr1:27773219-27824443 +  1p35.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STX12  -     1p35.3   [Description]    (hg19-Feb_2009)
GoldenPathSTX12 - 1p35.3 [CytoView hg19]  STX12 - 1p35.3 [CytoView hg38]
ImmunoBaseENSG00000117758
Genome Data Viewer NCBISTX12 [Mapview hg19]  
OMIM606892   
Gene and transcription
Genbank (Entrez)AF070635 AF123769 AK095898 AK297585 AK299982
RefSeq transcript (Entrez)NM_177424
Consensus coding sequences : CCDS (NCBI)STX12
Gene ExpressionSTX12 [ NCBI-GEO ]   STX12 [ EBI - ARRAY_EXPRESS ]   STX12 [ SEEK ]   STX12 [ MEM ]
Gene Expression Viewer (FireBrowse)STX12 [ Firebrowse - Broad ]
GenevisibleExpression of STX12 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23673
GTEX Portal (Tissue expression)STX12
Human Protein AtlasENSG00000117758-STX12 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86Y82   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86Y82  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86Y82
PhosPhoSitePlusQ86Y82
Domaine pattern : Prosite (Expaxy)SYNTAXIN (PS00914)    T_SNARE (PS50192)   
Domains : Interpro (EBI)SNARE    Syntaxin/epimorphin_CS    Syntaxin_N    T_SNARE_dom   
Domain families : Pfam (Sanger)SNARE (PF05739)    Syntaxin_2 (PF14523)   
Domain families : Pfam (NCBI)pfam05739    pfam14523   
Domain families : Smart (EMBL)SynN (SM00503)  t_SNARE (SM00397)  
Conserved Domain (NCBI)STX12
PDB (RSDB)2DNX   
PDB Europe2DNX   
PDB (PDBSum)2DNX   
PDB (IMB)2DNX   
Structural Biology KnowledgeBase2DNX   
SCOP (Structural Classification of Proteins)2DNX   
CATH (Classification of proteins structures)2DNX   
SuperfamilyQ86Y82
AlphaFold pdb e-kbQ86Y82   
Human Protein Atlas [tissue]ENSG00000117758-STX12 [tissue]
HPRD06059
Protein Interaction databases
DIP (DOE-UCLA)Q86Y82
IntAct (EBI)Q86Y82
BioGRIDSTX12
STRING (EMBL)STX12
ZODIACSTX12
Ontologies - Pathways
QuickGOQ86Y82
Ontology : AmiGOautophagosome assembly  Golgi membrane  SNARE binding  phagophore assembly site  SNAP receptor activity  protein binding  nucleoplasm  Golgi apparatus  intracellular protein transport  vesicle fusion  synaptic vesicle  endomembrane system  integral component of membrane  integral component of synaptic vesicle membrane  SNARE complex  SNARE complex  early endosome membrane  vesicle  cholesterol efflux  intracellular membrane-bounded organelle  membrane raft  phagocytic vesicle  vesicle docking  protein stabilization  recycling endosome membrane  postsynaptic recycling endosome  
Ontology : EGO-EBIautophagosome assembly  Golgi membrane  SNARE binding  phagophore assembly site  SNAP receptor activity  protein binding  nucleoplasm  Golgi apparatus  intracellular protein transport  vesicle fusion  synaptic vesicle  endomembrane system  integral component of membrane  integral component of synaptic vesicle membrane  SNARE complex  SNARE complex  early endosome membrane  vesicle  cholesterol efflux  intracellular membrane-bounded organelle  membrane raft  phagocytic vesicle  vesicle docking  protein stabilization  recycling endosome membrane  postsynaptic recycling endosome  
Pathways : KEGGPhagosome   
NDEx NetworkSTX12
Atlas of Cancer Signalling NetworkSTX12
Wikipedia pathwaysSTX12
Orthology - Evolution
OrthoDB23673
GeneTree (enSembl)ENSG00000117758
Phylogenetic Trees/Animal Genes : TreeFamSTX12
Homologs : HomoloGeneSTX12
Homology/Alignments : Family Browser (UCSC)STX12
Gene fusions - Rearrangements
Fusion : QuiverSTX12
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTX12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STX12
dbVarSTX12
ClinVarSTX12
MonarchSTX12
1000_GenomesSTX12 
Exome Variant ServerSTX12
GNOMAD BrowserENSG00000117758
Varsome BrowserSTX12
ACMGSTX12 variants
VarityQ86Y82
Genomic Variants (DGV)STX12 [DGVbeta]
DECIPHERSTX12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTX12 
Mutations
ICGC Data PortalSTX12 
TCGA Data PortalSTX12 
Broad Tumor PortalSTX12
OASIS PortalSTX12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTX12  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSTX12
Mutations and Diseases : HGMDSTX12
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSTX12
DgiDB (Drug Gene Interaction Database)STX12
DoCM (Curated mutations)STX12
CIViC (Clinical Interpretations of Variants in Cancer)STX12
Cancer3DSTX12
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606892   
Orphanet
DisGeNETSTX12
MedgenSTX12
Genetic Testing Registry STX12
NextProtQ86Y82 [Medical]
GENETestsSTX12
Target ValidationSTX12
Huge Navigator STX12 [HugePedia]
ClinGenSTX12
Clinical trials, drugs, therapy
MyCancerGenomeSTX12
Protein Interactions : CTDSTX12
Pharm GKB GenePA36230
Pharm GKB PathwaysPA162355621   
PharosQ86Y82
Clinical trialSTX12
Miscellaneous
canSAR (ICR)STX12
HarmonizomeSTX12
DataMed IndexSTX12
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSTX12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:33:43 CEST 2021

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