STX3 (syntaxin 3)

2016-10-01  

Identity

HGNC
LOCATION
11q12.1
LOCUSID
ALIAS
STX3A
FUSION GENES

Other Information

Locus ID:

NCBI: 6809
MIM: 600876
HGNC: 11438
Ensembl: ENSG00000166900

Variants:

dbSNP: 6809
ClinVar: 6809
TCGA: ENSG00000166900
COSMIC: STX3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166900ENST00000337979Q13277
ENSG00000166900ENST00000337979Q53YE2
ENSG00000166900ENST00000528805A0A0C4DGE4
ENSG00000166900ENST00000529177Q13277
ENSG00000166900ENST00000530221E9PN33
ENSG00000166900ENST00000533637E9PQJ8
ENSG00000166900ENST00000633708A0A0J9YW33
ENSG00000166900ENST00000641815A0A286YF28

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
SNARE interactions in vesicular transportKEGGko04130
SNARE interactions in vesicular transportKEGGhsa04130
Synaptic vesicle cycleKEGGko04721
Synaptic vesicle cycleKEGGhsa04721
Immune SystemREACTOMER-HSA-168256
Cytokine Signaling in Immune systemREACTOMER-HSA-1280215
Signaling by InterleukinsREACTOMER-HSA-449147

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
247267552014Loss of syntaxin 3 causes variant microvillus inclusion disease.49
231323382013Syntaxin-3 regulates newcomer insulin granule exocytosis and compound fusion in pancreatic beta cells.32
265539292015Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.32
256738752015Rab11a regulates syntaxin 3 localization and microvillus assembly in enterocytes.28
198155362010The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.27
219818322011SNAP-23 and syntaxin-3 are required for chemokine release by mature human mast cells.21
121981392002Analysis of the Munc18b-syntaxin binding interface. Use of a mutant Munc18b to dissect the functions of syntaxins 2 and 3.16
213712342011A role for the SNARE protein syntaxin 3 in human cytomegalovirus morphogenesis.16
208442482010Syntaxin 3 is necessary for cAMP- and cGMP-regulated exocytosis of CFTR: implications for enterotoxigenic diarrhea.14

Citation

Dessen P

STX3 (syntaxin 3)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56217/stx3