Atlas of Genetics and Cytogenetics in Oncology and Haematology


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STX5 (syntaxin 5)

Identity

Alias_namesSTX5A
syntaxin 5A
Alias_symbol (synonym)SED5
Other alias
HGNC (Hugo) STX5
LocusID (NCBI) 6811
Atlas_Id 56302
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62574332 and ends at 62599563 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
STX5 (11q12.3) / CFLAR (2q33.1)STX5 (11q12.3) / DZIP1 (13q32.1)STX5 (11q12.3) / WDR74 (11q12.3)
TMEM223 (11q12.3) / STX5 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STX5   11440
Cards
Entrez_Gene (NCBI)STX5  6811  syntaxin 5
AliasesSED5; STX5A
GeneCards (Weizmann)STX5
Ensembl hg19 (Hinxton)ENSG00000162236 [Gene_View]  chr11:62574332-62599563 [Contig_View]  STX5 [Vega]
Ensembl hg38 (Hinxton)ENSG00000162236 [Gene_View]  chr11:62574332-62599563 [Contig_View]  STX5 [Vega]
ICGC DataPortalENSG00000162236
TCGA cBioPortalSTX5
AceView (NCBI)STX5
Genatlas (Paris)STX5
WikiGenes6811
SOURCE (Princeton)STX5
Genetics Home Reference (NIH)STX5
Genomic and cartography
GoldenPath hg19 (UCSC)STX5  -     chr11:62574332-62599563 -  11q12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)STX5  -     11q12.3   [Description]    (hg38-Dec_2013)
EnsemblSTX5 - 11q12.3 [CytoView hg19]  STX5 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBISTX5 [Mapview hg19]  STX5 [Mapview hg38]
OMIM603189   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001244666 NM_001330294 NM_003164
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STX5
Cluster EST : UnigeneHs.654602 [ NCBI ]
CGAP (NCI)Hs.654602
Alternative Splicing GalleryENSG00000162236
Gene ExpressionSTX5 [ NCBI-GEO ]   STX5 [ EBI - ARRAY_EXPRESS ]   STX5 [ SEEK ]   STX5 [ MEM ]
Gene Expression Viewer (FireBrowse)STX5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6811
GTEX Portal (Tissue expression)STX5
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13190   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ13190  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ13190
Splice isoforms : SwissVarQ13190
PhosPhoSitePlusQ13190
Domaine pattern : Prosite (Expaxy)SYNTAXIN (PS00914)    T_SNARE (PS50192)   
Domains : Interpro (EBI)Syntaxin-5_N    Syntaxin/epimorphin_CS    t-SNARE    T_SNARE_dom   
Domain families : Pfam (Sanger)SNARE (PF05739)    Syntaxin-5_N (PF11416)   
Domain families : Pfam (NCBI)pfam05739    pfam11416   
Domain families : Smart (EMBL)t_SNARE (SM00397)  
Conserved Domain (NCBI)STX5
DMDM Disease mutations6811
Blocks (Seattle)STX5
PDB (SRS)3EFO   
PDB (PDBSum)3EFO   
PDB (IMB)3EFO   
PDB (RSDB)3EFO   
Structural Biology KnowledgeBase3EFO   
SCOP (Structural Classification of Proteins)3EFO   
CATH (Classification of proteins structures)3EFO   
SuperfamilyQ13190
Human Protein AtlasENSG00000162236
Peptide AtlasQ13190
HPRD04426
IPIIPI00744834   IPI00386786   IPI00784899   IPI00788072   IPI00984208   IPI00984893   IPI00983519   IPI00977432   
Protein Interaction databases
DIP (DOE-UCLA)Q13190
IntAct (EBI)Q13190
FunCoupENSG00000162236
BioGRIDSTX5
STRING (EMBL)STX5
ZODIACSTX5
Ontologies - Pathways
QuickGOQ13190
Ontology : AmiGOGolgi membrane  Golgi membrane  SNARE binding  SNAP receptor activity  protein binding  nucleoplasm  endoplasmic reticulum membrane  Golgi apparatus  cytosol  cell-cell adherens junction  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  vesicle fusion  ER to Golgi transport vesicle membrane  integral component of membrane  SNARE complex  vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  early endosome to Golgi transport  retrograde transport, endosome to Golgi  positive regulation of protein catabolic process  protein N-terminus binding  COPII vesicle coating  vesicle docking  vesicle fusion with Golgi apparatus  Golgi disassembly  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  regulation of Golgi organization  
Ontology : EGO-EBIGolgi membrane  Golgi membrane  SNARE binding  SNAP receptor activity  protein binding  nucleoplasm  endoplasmic reticulum membrane  Golgi apparatus  cytosol  cell-cell adherens junction  intracellular protein transport  ER to Golgi vesicle-mediated transport  ER to Golgi vesicle-mediated transport  vesicle fusion  ER to Golgi transport vesicle membrane  integral component of membrane  SNARE complex  vesicle  endoplasmic reticulum-Golgi intermediate compartment membrane  early endosome to Golgi transport  retrograde transport, endosome to Golgi  positive regulation of protein catabolic process  protein N-terminus binding  COPII vesicle coating  vesicle docking  vesicle fusion with Golgi apparatus  Golgi disassembly  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  regulation of Golgi organization  
Pathways : KEGGSNARE interactions in vesicular transport   
NDEx NetworkSTX5
Atlas of Cancer Signalling NetworkSTX5
Wikipedia pathwaysSTX5
Orthology - Evolution
OrthoDB6811
GeneTree (enSembl)ENSG00000162236
Phylogenetic Trees/Animal Genes : TreeFamSTX5
HOVERGENQ13190
HOGENOMQ13190
Homologs : HomoloGeneSTX5
Homology/Alignments : Family Browser (UCSC)STX5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTX5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STX5
dbVarSTX5
ClinVarSTX5
1000_GenomesSTX5 
Exome Variant ServerSTX5
ExAC (Exome Aggregation Consortium)STX5 (select the gene name)
Genetic variants : HAPMAP6811
Genomic Variants (DGV)STX5 [DGVbeta]
DECIPHER (Syndromes)11:62574332-62599563  ENSG00000162236
CONAN: Copy Number AnalysisSTX5 
Mutations
ICGC Data PortalSTX5 
TCGA Data PortalSTX5 
Broad Tumor PortalSTX5
OASIS PortalSTX5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTX5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTX5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STX5
DgiDB (Drug Gene Interaction Database)STX5
DoCM (Curated mutations)STX5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STX5 (select a term)
intoGenSTX5
Cancer3DSTX5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603189   
Orphanet
MedgenSTX5
Genetic Testing Registry STX5
NextProtQ13190 [Medical]
TSGene6811
GENETestsSTX5
Huge Navigator STX5 [HugePedia]
snp3D : Map Gene to Disease6811
BioCentury BCIQSTX5
ClinGenSTX5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6811
Chemical/Pharm GKB GenePA36237
Clinical trialSTX5
Miscellaneous
canSAR (ICR)STX5 (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTX5
EVEXSTX5
GoPubMedSTX5
iHOPSTX5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:21:23 CEST 2017

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