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STX8 (syntaxin 8)

Identity

Alias_symbol (synonym)CARB
Other alias
HGNC (Hugo) STX8
LocusID (NCBI) 9482
Atlas_Id 56267
Location 17p13.1  [Link to chromosome band 17p13]
Location_base_pair Starts at 9250471 and ends at 9575958 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
IKBKE (1q32.1) / STX8 (17p13.1)NTN1 (17p13.1) / STX8 (17p13.1)PITPNM3 (17p13.2) / STX8 (17p13.1)
STX8 (17p13.1) / AKAP13 (15q25.3)STX8 (17p13.1) / HSD17B4 (5q23.1)STX8 (17p13.1) / ULK4 (3p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STX8   11443
Cards
Entrez_Gene (NCBI)STX8  9482  syntaxin 8
AliasesCARB
GeneCards (Weizmann)STX8
Ensembl hg19 (Hinxton)ENSG00000170310 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000170310 [Gene_View]  chr17:9250471-9575958 [Contig_View]  STX8 [Vega]
ICGC DataPortalENSG00000170310
TCGA cBioPortalSTX8
AceView (NCBI)STX8
Genatlas (Paris)STX8
WikiGenes9482
SOURCE (Princeton)STX8
Genetics Home Reference (NIH)STX8
Genomic and cartography
GoldenPath hg38 (UCSC)STX8  -     chr17:9250471-9575958 -  17p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STX8  -     17p13.1   [Description]    (hg19-Feb_2009)
EnsemblSTX8 - 17p13.1 [CytoView hg19]  STX8 - 17p13.1 [CytoView hg38]
Mapping of homologs : NCBISTX8 [Mapview hg19]  STX8 [Mapview hg38]
OMIM604203   
Gene and transcription
Genbank (Entrez)AF036715 AF062077 AF115323 BC009713 BC020924
RefSeq transcript (Entrez)NM_004853
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STX8
Cluster EST : UnigeneHs.431109 [ NCBI ]
CGAP (NCI)Hs.431109
Alternative Splicing GalleryENSG00000170310
Gene ExpressionSTX8 [ NCBI-GEO ]   STX8 [ EBI - ARRAY_EXPRESS ]   STX8 [ SEEK ]   STX8 [ MEM ]
Gene Expression Viewer (FireBrowse)STX8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9482
GTEX Portal (Tissue expression)STX8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UNK0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UNK0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UNK0
Splice isoforms : SwissVarQ9UNK0
PhosPhoSitePlusQ9UNK0
Domaine pattern : Prosite (Expaxy)T_SNARE (PS50192)   
Domains : Interpro (EBI)T_SNARE_dom   
Domain families : Pfam (Sanger)SNARE (PF05739)   
Domain families : Pfam (NCBI)pfam05739   
Domain families : Smart (EMBL)t_SNARE (SM00397)  
Conserved Domain (NCBI)STX8
DMDM Disease mutations9482
Blocks (Seattle)STX8
SuperfamilyQ9UNK0
Human Protein AtlasENSG00000170310
Peptide AtlasQ9UNK0
HPRD05012
IPIIPI00009225   
Protein Interaction databases
DIP (DOE-UCLA)Q9UNK0
IntAct (EBI)Q9UNK0
FunCoupENSG00000170310
BioGRIDSTX8
STRING (EMBL)STX8
ZODIACSTX8
Ontologies - Pathways
QuickGOQ9UNK0
Ontology : AmiGOSNAP receptor activity  protein binding  lysosomal membrane  endosome  early endosome  late endosome  endoplasmic reticulum  trans-Golgi network  cytosol  integral component of plasma membrane  transport  intracellular protein transport  vesicle fusion  endosome to lysosome transport  chloride channel inhibitor activity  syntaxin binding  SNARE complex  ubiquitin protein ligase binding  late endosome membrane  vesicle  early endosome to late endosome transport  vesicle docking  perinuclear region of cytoplasm  recycling endosome  regulation of molecular function  regulation of protein localization to plasma membrane  
Ontology : EGO-EBISNAP receptor activity  protein binding  lysosomal membrane  endosome  early endosome  late endosome  endoplasmic reticulum  trans-Golgi network  cytosol  integral component of plasma membrane  transport  intracellular protein transport  vesicle fusion  endosome to lysosome transport  chloride channel inhibitor activity  syntaxin binding  SNARE complex  ubiquitin protein ligase binding  late endosome membrane  vesicle  early endosome to late endosome transport  vesicle docking  perinuclear region of cytoplasm  recycling endosome  regulation of molecular function  regulation of protein localization to plasma membrane  
Pathways : KEGGSNARE interactions in vesicular transport   
NDEx NetworkSTX8
Atlas of Cancer Signalling NetworkSTX8
Wikipedia pathwaysSTX8
Orthology - Evolution
OrthoDB9482
GeneTree (enSembl)ENSG00000170310
Phylogenetic Trees/Animal Genes : TreeFamSTX8
HOVERGENQ9UNK0
HOGENOMQ9UNK0
Homologs : HomoloGeneSTX8
Homology/Alignments : Family Browser (UCSC)STX8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTX8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STX8
dbVarSTX8
ClinVarSTX8
1000_GenomesSTX8 
Exome Variant ServerSTX8
ExAC (Exome Aggregation Consortium)STX8 (select the gene name)
Genetic variants : HAPMAP9482
Genomic Variants (DGV)STX8 [DGVbeta]
DECIPHERSTX8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTX8 
Mutations
ICGC Data PortalSTX8 
TCGA Data PortalSTX8 
Broad Tumor PortalSTX8
OASIS PortalSTX8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTX8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTX8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STX8
DgiDB (Drug Gene Interaction Database)STX8
DoCM (Curated mutations)STX8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STX8 (select a term)
intoGenSTX8
Cancer3DSTX8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604203   
Orphanet
MedgenSTX8
Genetic Testing Registry STX8
NextProtQ9UNK0 [Medical]
TSGene9482
GENETestsSTX8
Huge Navigator STX8 [HugePedia]
snp3D : Map Gene to Disease9482
BioCentury BCIQSTX8
ClinGenSTX8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9482
Chemical/Pharm GKB GenePA36240
Clinical trialSTX8
Miscellaneous
canSAR (ICR)STX8 (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTX8
EVEXSTX8
GoPubMedSTX8
iHOPSTX8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:39:44 CEST 2017

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