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STYX (serine/threonine/tyrosine interacting protein)

Identity

Alias_namesserine/threonine/tyrosine-interacting protein
Other alias-
HGNC (Hugo) STYX
LocusID (NCBI) 6815
Atlas_Id 74349
Location 14q22.1  [Link to chromosome band 14q22]
Location_base_pair Starts at 52730165 and ends at 52774987 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CTSS (1q21.3) / STYX (14q22.1)GNPNAT1 (14q22.1) / STYX (14q22.1)PAG1 (8q21.13) / STYX (14q22.1)
STYX (14q22.1) / STYX (14q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STYX   11447
Cards
Entrez_Gene (NCBI)STYX  6815  serine/threonine/tyrosine interacting protein
Aliases
GeneCards (Weizmann)STYX
Ensembl hg19 (Hinxton)ENSG00000198252 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198252 [Gene_View]  chr14:52730165-52774987 [Contig_View]  STYX [Vega]
ICGC DataPortalENSG00000198252
TCGA cBioPortalSTYX
AceView (NCBI)STYX
Genatlas (Paris)STYX
WikiGenes6815
SOURCE (Princeton)STYX
Genetics Home Reference (NIH)STYX
Genomic and cartography
GoldenPath hg38 (UCSC)STYX  -     chr14:52730165-52774987 +  14q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STYX  -     14q22.1   [Description]    (hg19-Feb_2009)
EnsemblSTYX - 14q22.1 [CytoView hg19]  STYX - 14q22.1 [CytoView hg38]
Mapping of homologs : NCBISTYX [Mapview hg19]  STYX [Mapview hg38]
OMIM615814   
Gene and transcription
Genbank (Entrez)AF085865 AK098195 AK124924 AL832591 AL832697
RefSeq transcript (Entrez)NM_001130701 NM_145251
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STYX
Cluster EST : UnigeneHs.364980 [ NCBI ]
CGAP (NCI)Hs.364980
Alternative Splicing GalleryENSG00000198252
Gene ExpressionSTYX [ NCBI-GEO ]   STYX [ EBI - ARRAY_EXPRESS ]   STYX [ SEEK ]   STYX [ MEM ]
Gene Expression Viewer (FireBrowse)STYX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6815
GTEX Portal (Tissue expression)STYX
Human Protein AtlasENSG00000198252-STYX [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WUJ0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WUJ0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WUJ0
Splice isoforms : SwissVarQ8WUJ0
PhosPhoSitePlusQ8WUJ0
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_2 (PS50056)    TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP    Prot-tyrosine_phosphatase-like    TYR_PHOSPHATASE_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)   
Domain families : Pfam (NCBI)pfam00782   
Domain families : Smart (EMBL)DSPc (SM00195)  
Conserved Domain (NCBI)STYX
DMDM Disease mutations6815
Blocks (Seattle)STYX
PDB (SRS)2R0B   
PDB (PDBSum)2R0B   
PDB (IMB)2R0B   
PDB (RSDB)2R0B   
Structural Biology KnowledgeBase2R0B   
SCOP (Structural Classification of Proteins)2R0B   
CATH (Classification of proteins structures)2R0B   
SuperfamilyQ8WUJ0
Human Protein Atlas [tissue]ENSG00000198252-STYX [tissue]
Peptide AtlasQ8WUJ0
HPRD10258
IPIIPI00102927   
Protein Interaction databases
DIP (DOE-UCLA)Q8WUJ0
IntAct (EBI)Q8WUJ0
FunCoupENSG00000198252
BioGRIDSTYX
STRING (EMBL)STYX
ZODIACSTYX
Ontologies - Pathways
QuickGOQ8WUJ0
Ontology : AmiGOprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  protein dephosphorylation  spermatogenesis  protein tyrosine/serine/threonine phosphatase activity  MAPK export from nucleus  regulation of ERK1 and ERK2 cascade  
Ontology : EGO-EBIprotein binding  nucleus  nucleoplasm  cytoplasm  cytosol  protein dephosphorylation  spermatogenesis  protein tyrosine/serine/threonine phosphatase activity  MAPK export from nucleus  regulation of ERK1 and ERK2 cascade  
NDEx NetworkSTYX
Atlas of Cancer Signalling NetworkSTYX
Wikipedia pathwaysSTYX
Orthology - Evolution
OrthoDB6815
GeneTree (enSembl)ENSG00000198252
Phylogenetic Trees/Animal Genes : TreeFamSTYX
HOVERGENQ8WUJ0
HOGENOMQ8WUJ0
Homologs : HomoloGeneSTYX
Homology/Alignments : Family Browser (UCSC)STYX
Gene fusions - Rearrangements
Fusion: Tumor Portal STYX
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTYX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STYX
dbVarSTYX
ClinVarSTYX
1000_GenomesSTYX 
Exome Variant ServerSTYX
ExAC (Exome Aggregation Consortium)ENSG00000198252
GNOMAD BrowserENSG00000198252
Genetic variants : HAPMAP6815
Genomic Variants (DGV)STYX [DGVbeta]
DECIPHERSTYX [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTYX 
Mutations
ICGC Data PortalSTYX 
TCGA Data PortalSTYX 
Broad Tumor PortalSTYX
OASIS PortalSTYX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTYX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTYX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STYX
DgiDB (Drug Gene Interaction Database)STYX
DoCM (Curated mutations)STYX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STYX (select a term)
intoGenSTYX
Cancer3DSTYX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615814   
Orphanet
MedgenSTYX
Genetic Testing Registry STYX
NextProtQ8WUJ0 [Medical]
TSGene6815
GENETestsSTYX
Target ValidationSTYX
Huge Navigator STYX [HugePedia]
snp3D : Map Gene to Disease6815
BioCentury BCIQSTYX
ClinGenSTYX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6815
Chemical/Pharm GKB GenePA36244
Clinical trialSTYX
Miscellaneous
canSAR (ICR)STYX (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTYX
EVEXSTYX
GoPubMedSTYX
iHOPSTYX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:31:20 CET 2017

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