Atlas of Genetics and Cytogenetics in Oncology and Haematology


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STYXL1 (serine/threonine/tyrosine interacting like 1)

Identity

Alias_namesDUSP24
dual specificity phosphatase 24 (putative)
Alias_symbol (synonym)MK-STYX
Other aliasMKSTYX
HGNC (Hugo) STYXL1
LocusID (NCBI) 51657
Atlas_Id 74350
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 75996337 and ends at 76048003 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CKAP4 (12q23.3) / STYXL1 (7q11.23)GSAP (7q11.23) / STYXL1 (7q11.23)STYXL1 (7q11.23) / BCR (22q11.23)
STYXL1 (7q11.23) / PPIL2 (22q11.21)STYXL1 (7q11.23) / TMEM120A (7q11.23)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)STYXL1   18165
Cards
Entrez_Gene (NCBI)STYXL1  51657  serine/threonine/tyrosine interacting like 1
AliasesDUSP24; MK-STYX; MKSTYX
GeneCards (Weizmann)STYXL1
Ensembl hg19 (Hinxton)ENSG00000127952 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000127952 [Gene_View]  chr7:75996337-76048003 [Contig_View]  STYXL1 [Vega]
ICGC DataPortalENSG00000127952
TCGA cBioPortalSTYXL1
AceView (NCBI)STYXL1
Genatlas (Paris)STYXL1
WikiGenes51657
SOURCE (Princeton)STYXL1
Genetics Home Reference (NIH)STYXL1
Genomic and cartography
GoldenPath hg38 (UCSC)STYXL1  -     chr7:75996337-76048003 -  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)STYXL1  -     7q11.23   [Description]    (hg19-Feb_2009)
EnsemblSTYXL1 - 7q11.23 [CytoView hg19]  STYXL1 - 7q11.23 [CytoView hg38]
Mapping of homologs : NCBISTYXL1 [Mapview hg19]  STYXL1 [Mapview hg38]
OMIM616695   
Gene and transcription
Genbank (Entrez)AA782050 AF069762 AF169647 AF169648 AF188201
RefSeq transcript (Entrez)NM_001317785 NM_001317786 NM_001317787 NM_001317788 NM_001317789 NM_016086
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)STYXL1
Cluster EST : UnigeneHs.11615 [ NCBI ]
CGAP (NCI)Hs.11615
Alternative Splicing GalleryENSG00000127952
Gene ExpressionSTYXL1 [ NCBI-GEO ]   STYXL1 [ EBI - ARRAY_EXPRESS ]   STYXL1 [ SEEK ]   STYXL1 [ MEM ]
Gene Expression Viewer (FireBrowse)STYXL1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51657
GTEX Portal (Tissue expression)STYXL1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6J8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6J8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6J8
Splice isoforms : SwissVarQ9Y6J8
PhosPhoSitePlusQ9Y6J8
Domaine pattern : Prosite (Expaxy)TYR_PHOSPHATASE_DUAL (PS50054)   
Domains : Interpro (EBI)Dual-sp_phosphatase_cat-dom    DUSP    Prot-tyrosine_phosphatase-like    Rhodanese-like_dom    TYR_PHOSPHATASE_DUAL_dom   
Domain families : Pfam (Sanger)DSPc (PF00782)    Rhodanese (PF00581)   
Domain families : Pfam (NCBI)pfam00782    pfam00581   
Domain families : Smart (EMBL)DSPc (SM00195)  RHOD (SM00450)  
Conserved Domain (NCBI)STYXL1
DMDM Disease mutations51657
Blocks (Seattle)STYXL1
SuperfamilyQ9Y6J8
Human Protein AtlasENSG00000127952
Peptide AtlasQ9Y6J8
HPRD13256
IPIIPI00007125   IPI00220190   IPI00220191   IPI00220192   IPI00220193   IPI00925442   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6J8
IntAct (EBI)Q9Y6J8
FunCoupENSG00000127952
BioGRIDSTYXL1
STRING (EMBL)STYXL1
ZODIACSTYXL1
Ontologies - Pathways
QuickGOQ9Y6J8
Ontology : AmiGOintracellular  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  intracellular signal transduction  
Ontology : EGO-EBIintracellular  protein dephosphorylation  protein tyrosine/serine/threonine phosphatase activity  intracellular signal transduction  
NDEx NetworkSTYXL1
Atlas of Cancer Signalling NetworkSTYXL1
Wikipedia pathwaysSTYXL1
Orthology - Evolution
OrthoDB51657
GeneTree (enSembl)ENSG00000127952
Phylogenetic Trees/Animal Genes : TreeFamSTYXL1
HOVERGENQ9Y6J8
HOGENOMQ9Y6J8
Homologs : HomoloGeneSTYXL1
Homology/Alignments : Family Browser (UCSC)STYXL1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSTYXL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)STYXL1
dbVarSTYXL1
ClinVarSTYXL1
1000_GenomesSTYXL1 
Exome Variant ServerSTYXL1
ExAC (Exome Aggregation Consortium)STYXL1 (select the gene name)
Genetic variants : HAPMAP51657
Genomic Variants (DGV)STYXL1 [DGVbeta]
DECIPHERSTYXL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSTYXL1 
Mutations
ICGC Data PortalSTYXL1 
TCGA Data PortalSTYXL1 
Broad Tumor PortalSTYXL1
OASIS PortalSTYXL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSTYXL1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSTYXL1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch STYXL1
DgiDB (Drug Gene Interaction Database)STYXL1
DoCM (Curated mutations)STYXL1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)STYXL1 (select a term)
intoGenSTYXL1
Cancer3DSTYXL1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616695   
Orphanet
MedgenSTYXL1
Genetic Testing Registry STYXL1
NextProtQ9Y6J8 [Medical]
TSGene51657
GENETestsSTYXL1
Target ValidationSTYXL1
Huge Navigator STYXL1 [HugePedia]
snp3D : Map Gene to Disease51657
BioCentury BCIQSTYXL1
ClinGenSTYXL1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51657
Chemical/Pharm GKB GenePA134942462
Clinical trialSTYXL1
Miscellaneous
canSAR (ICR)STYXL1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSTYXL1
EVEXSTYXL1
GoPubMedSTYXL1
iHOPSTYXL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:44:29 CEST 2017

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