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SUCLG2 (succinate-CoA ligase GDP-forming beta subunit)

Identity

Other aliasG-SCS
GBETA
GTPSCS
HGNC (Hugo) SUCLG2
LocusID (NCBI) 8801
Atlas_Id 74354
Location 3p14.1  [Link to chromosome band 3p14]
Location_base_pair Starts at 67360460 and ends at 67654614 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM19A1 (3p14.1) / SUCLG2 (3p14.1)LRIG1 (3p14.1) / SUCLG2 (3p14.1)SUCLG2 (3p14.1) / RBP4 (10q23.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SUCLG2   11450
Cards
Entrez_Gene (NCBI)SUCLG2  8801  succinate-CoA ligase GDP-forming beta subunit
AliasesG-SCS; GBETA; GTPSCS
GeneCards (Weizmann)SUCLG2
Ensembl hg19 (Hinxton)ENSG00000172340 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172340 [Gene_View]  chr3:67360460-67654614 [Contig_View]  SUCLG2 [Vega]
ICGC DataPortalENSG00000172340
TCGA cBioPortalSUCLG2
AceView (NCBI)SUCLG2
Genatlas (Paris)SUCLG2
WikiGenes8801
SOURCE (Princeton)SUCLG2
Genetics Home Reference (NIH)SUCLG2
Genomic and cartography
GoldenPath hg38 (UCSC)SUCLG2  -     chr3:67360460-67654614 -  3p14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUCLG2  -     3p14.1   [Description]    (hg19-Feb_2009)
EnsemblSUCLG2 - 3p14.1 [CytoView hg19]  SUCLG2 - 3p14.1 [CytoView hg38]
Mapping of homologs : NCBISUCLG2 [Mapview hg19]  SUCLG2 [Mapview hg38]
OMIM603922   
Gene and transcription
Genbank (Entrez)AF058954 AF131748 AK294598 AK310527 AL050226
RefSeq transcript (Entrez)NM_001177599 NM_003848
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SUCLG2
Cluster EST : UnigeneHs.644919 [ NCBI ]
CGAP (NCI)Hs.644919
Alternative Splicing GalleryENSG00000172340
Gene ExpressionSUCLG2 [ NCBI-GEO ]   SUCLG2 [ EBI - ARRAY_EXPRESS ]   SUCLG2 [ SEEK ]   SUCLG2 [ MEM ]
Gene Expression Viewer (FireBrowse)SUCLG2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8801
GTEX Portal (Tissue expression)SUCLG2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96I99   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96I99  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96I99
Splice isoforms : SwissVarQ96I99
PhosPhoSitePlusQ96I99
Domaine pattern : Prosite (Expaxy)SUCCINYL_COA_LIG_3 (PS01217)   
Domains : Interpro (EBI)ATP-grasp_succ-CoA_synth-type    ATP_grasp_subdomain_1    ATP_grasp_subdomain_2    CoA_ligase    Succ-CoA_synthase_bsu_CS    Succ_CoA_synthase_bsu    Succinyl-CoA_synth-like   
Domain families : Pfam (Sanger)ATP-grasp_2 (PF08442)    Ligase_CoA (PF00549)   
Domain families : Pfam (NCBI)pfam08442    pfam00549   
Conserved Domain (NCBI)SUCLG2
DMDM Disease mutations8801
Blocks (Seattle)SUCLG2
SuperfamilyQ96I99
Human Protein AtlasENSG00000172340
Peptide AtlasQ96I99
HPRD06799
IPIIPI00096066   IPI00155466   IPI00945507   IPI00921931   
Protein Interaction databases
DIP (DOE-UCLA)Q96I99
IntAct (EBI)Q96I99
FunCoupENSG00000172340
BioGRIDSUCLG2
STRING (EMBL)SUCLG2
ZODIACSUCLG2
Ontologies - Pathways
QuickGOQ96I99
Ontology : AmiGOsuccinate-CoA ligase (GDP-forming) activity  ATP binding  GTP binding  mitochondrion  mitochondrial matrix  plasma membrane  tricarboxylic acid cycle  tricarboxylic acid cycle  succinyl-CoA metabolic process  succinate metabolic process  GDP binding  succinate-CoA ligase complex (GDP-forming)  metal ion binding  protein heterodimerization activity  
Ontology : EGO-EBIsuccinate-CoA ligase (GDP-forming) activity  ATP binding  GTP binding  mitochondrion  mitochondrial matrix  plasma membrane  tricarboxylic acid cycle  tricarboxylic acid cycle  succinyl-CoA metabolic process  succinate metabolic process  GDP binding  succinate-CoA ligase complex (GDP-forming)  metal ion binding  protein heterodimerization activity  
Pathways : KEGGCitrate cycle (TCA cycle)    Propanoate metabolism   
NDEx NetworkSUCLG2
Atlas of Cancer Signalling NetworkSUCLG2
Wikipedia pathwaysSUCLG2
Orthology - Evolution
OrthoDB8801
GeneTree (enSembl)ENSG00000172340
Phylogenetic Trees/Animal Genes : TreeFamSUCLG2
HOVERGENQ96I99
HOGENOMQ96I99
Homologs : HomoloGeneSUCLG2
Homology/Alignments : Family Browser (UCSC)SUCLG2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUCLG2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUCLG2
dbVarSUCLG2
ClinVarSUCLG2
1000_GenomesSUCLG2 
Exome Variant ServerSUCLG2
ExAC (Exome Aggregation Consortium)SUCLG2 (select the gene name)
Genetic variants : HAPMAP8801
Genomic Variants (DGV)SUCLG2 [DGVbeta]
DECIPHERSUCLG2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUCLG2 
Mutations
ICGC Data PortalSUCLG2 
TCGA Data PortalSUCLG2 
Broad Tumor PortalSUCLG2
OASIS PortalSUCLG2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUCLG2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSUCLG2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SUCLG2
DgiDB (Drug Gene Interaction Database)SUCLG2
DoCM (Curated mutations)SUCLG2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUCLG2 (select a term)
intoGenSUCLG2
Cancer3DSUCLG2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603922   
Orphanet
MedgenSUCLG2
Genetic Testing Registry SUCLG2
NextProtQ96I99 [Medical]
TSGene8801
GENETestsSUCLG2
Target ValidationSUCLG2
Huge Navigator SUCLG2 [HugePedia]
snp3D : Map Gene to Disease8801
BioCentury BCIQSUCLG2
ClinGenSUCLG2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8801
Chemical/Pharm GKB GenePA36247
Clinical trialSUCLG2
Miscellaneous
canSAR (ICR)SUCLG2 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUCLG2
EVEXSUCLG2
GoPubMedSUCLG2
iHOPSUCLG2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:44:30 CEST 2017

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