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SULT1B1 (sulfotransferase family 1B member 1)

Identity

Alias (NCBI)ST1B1
ST1B2
SULT1B2
HGNC (Hugo) SULT1B1
HGNC Alias symbST1B2
HGNC Previous namesulfotransferase family, cytosolic, 1B, member 1
LocusID (NCBI) 27284
Atlas_Id 74364
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 69726968 and ends at 69760712 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SULT1B1 (4q13.3) / CSN2 (4q13.3)YTHDC1 (4q13.2) / SULT1B1 (4q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  SULT1B1/CSN2 (4q13)
YTHDC1/SULT1B1 (4q13)


External links

Nomenclature
HGNC (Hugo)SULT1B1   17845
Cards
Entrez_Gene (NCBI)SULT1B1  27284  sulfotransferase family 1B member 1
AliasesST1B1; ST1B2; SULT1B2
GeneCards (Weizmann)SULT1B1
Ensembl hg19 (Hinxton)ENSG00000173597 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000173597 [Gene_View]  ENSG00000173597 [Sequence]  chr4:69726968-69760712 [Contig_View]  SULT1B1 [Vega]
ICGC DataPortalENSG00000173597
TCGA cBioPortalSULT1B1
AceView (NCBI)SULT1B1
Genatlas (Paris)SULT1B1
WikiGenes27284
SOURCE (Princeton)SULT1B1
Genetics Home Reference (NIH)SULT1B1
Genomic and cartography
GoldenPath hg38 (UCSC)SULT1B1  -     chr4:69726968-69760712 -  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SULT1B1  -     4q13.3   [Description]    (hg19-Feb_2009)
GoldenPathSULT1B1 - 4q13.3 [CytoView hg19]  SULT1B1 - 4q13.3 [CytoView hg38]
ImmunoBaseENSG00000173597
genome Data Viewer NCBISULT1B1 [Mapview hg19]  
OMIM608436   
Gene and transcription
Genbank (Entrez)BC010895 BG461453 D89479 U95726
RefSeq transcript (Entrez)NM_014465
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SULT1B1
Alternative Splicing GalleryENSG00000173597
Gene ExpressionSULT1B1 [ NCBI-GEO ]   SULT1B1 [ EBI - ARRAY_EXPRESS ]   SULT1B1 [ SEEK ]   SULT1B1 [ MEM ]
Gene Expression Viewer (FireBrowse)SULT1B1 [ Firebrowse - Broad ]
GenevisibleExpression of SULT1B1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27284
GTEX Portal (Tissue expression)SULT1B1
Human Protein AtlasENSG00000173597-SULT1B1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43704   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43704  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43704
Splice isoforms : SwissVarO43704
Catalytic activity : Enzyme2.8.2.- [ Enzyme-Expasy ]   2.8.2.-2.8.2.- [ IntEnz-EBI ]   2.8.2.- [ BRENDA ]   2.8.2.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusO43704
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom    SULT1B1   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)SULT1B1
DMDM Disease mutations27284
Blocks (Seattle)SULT1B1
PDB (RSDB)2Z5F    3CKL   
PDB Europe2Z5F    3CKL   
PDB (PDBSum)2Z5F    3CKL   
PDB (IMB)2Z5F    3CKL   
Structural Biology KnowledgeBase2Z5F    3CKL   
SCOP (Structural Classification of Proteins)2Z5F    3CKL   
CATH (Classification of proteins structures)2Z5F    3CKL   
SuperfamilyO43704
Human Protein Atlas [tissue]ENSG00000173597-SULT1B1 [tissue]
Peptide AtlasO43704
HPRD07088
IPIIPI00102581   IPI00966178   IPI00968156   
Protein Interaction databases
DIP (DOE-UCLA)O43704
IntAct (EBI)O43704
FunCoupENSG00000173597
BioGRIDSULT1B1
STRING (EMBL)SULT1B1
ZODIACSULT1B1
Ontologies - Pathways
QuickGOO43704
Ontology : AmiGOaryl sulfotransferase activity  protein binding  cytosol  cytosol  ethanol catabolic process  cellular biogenic amine metabolic process  xenobiotic metabolic process  sulfotransferase activity  steroid metabolic process  flavonoid metabolic process  phenol-containing compound metabolic process  epithelial cell differentiation  thyroid hormone metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Ontology : EGO-EBIaryl sulfotransferase activity  protein binding  cytosol  cytosol  ethanol catabolic process  cellular biogenic amine metabolic process  xenobiotic metabolic process  sulfotransferase activity  steroid metabolic process  flavonoid metabolic process  phenol-containing compound metabolic process  epithelial cell differentiation  thyroid hormone metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Pathways : KEGGCysteine metabolism   
NDEx NetworkSULT1B1
Atlas of Cancer Signalling NetworkSULT1B1
Wikipedia pathwaysSULT1B1
Orthology - Evolution
OrthoDB27284
GeneTree (enSembl)ENSG00000173597
Phylogenetic Trees/Animal Genes : TreeFamSULT1B1
HOGENOMO43704
Homologs : HomoloGeneSULT1B1
Homology/Alignments : Family Browser (UCSC)SULT1B1
Gene fusions - Rearrangements
Fusion : QuiverSULT1B1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSULT1B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SULT1B1
dbVarSULT1B1
ClinVarSULT1B1
1000_GenomesSULT1B1 
Exome Variant ServerSULT1B1
GNOMAD BrowserENSG00000173597
Varsome BrowserSULT1B1
Genetic variants : HAPMAP27284
Genomic Variants (DGV)SULT1B1 [DGVbeta]
DECIPHERSULT1B1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSULT1B1 
Mutations
ICGC Data PortalSULT1B1 
TCGA Data PortalSULT1B1 
Broad Tumor PortalSULT1B1
OASIS PortalSULT1B1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSULT1B1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSULT1B1
Mutations and Diseases : HGMDSULT1B1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SULT1B1
DgiDB (Drug Gene Interaction Database)SULT1B1
DoCM (Curated mutations)SULT1B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SULT1B1 (select a term)
intoGenSULT1B1
Cancer3DSULT1B1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608436   
Orphanet
DisGeNETSULT1B1
MedgenSULT1B1
Genetic Testing Registry SULT1B1
NextProtO43704 [Medical]
TSGene27284
GENETestsSULT1B1
Target ValidationSULT1B1
Huge Navigator SULT1B1 [HugePedia]
snp3D : Map Gene to Disease27284
BioCentury BCIQSULT1B1
ClinGenSULT1B1
Clinical trials, drugs, therapy
Protein Interactions : CTD27284
Pharm GKB GenePA415
Clinical trialSULT1B1
Miscellaneous
canSAR (ICR)SULT1B1 (select the gene name)
HarmonizomeSULT1B1
DataMed IndexSULT1B1
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSULT1B1
EVEXSULT1B1
GoPubMedSULT1B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Sat Aug 22 19:37:10 CEST 2020

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