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SULT2A1 (sulfotransferase family 2A member 1)

Identity

Alias_namesSTD
sulfotransferase family
Alias_symbol (synonym)DHEA-ST
Other aliasDHEAS
HST
ST2
ST2A1
ST2A3
hSTa
HGNC (Hugo) SULT2A1
LocusID (NCBI) 6822
Atlas_Id 46236
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 47870466 and ends at 47886397 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PPP2R1A (19q13.41) / SULT2A1 (19q13.33)SULT2A1 (19q13.33) / SERPINC1 (1q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SULT2A1   11458
Cards
Entrez_Gene (NCBI)SULT2A1  6822  sulfotransferase family 2A member 1
AliasesDHEA-ST; DHEAS; HST; ST2; 
ST2A1; ST2A3; STD; hSTa
GeneCards (Weizmann)SULT2A1
Ensembl hg19 (Hinxton)ENSG00000105398 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105398 [Gene_View]  chr19:47870466-47886397 [Contig_View]  SULT2A1 [Vega]
ICGC DataPortalENSG00000105398
TCGA cBioPortalSULT2A1
AceView (NCBI)SULT2A1
Genatlas (Paris)SULT2A1
WikiGenes6822
SOURCE (Princeton)SULT2A1
Genetics Home Reference (NIH)SULT2A1
Genomic and cartography
GoldenPath hg38 (UCSC)SULT2A1  -     chr19:47870466-47886397 -  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SULT2A1  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblSULT2A1 - 19q13.33 [CytoView hg19]  SULT2A1 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBISULT2A1 [Mapview hg19]  SULT2A1 [Mapview hg38]
OMIM125263   
Gene and transcription
Genbank (Entrez)AK289380 AK313415 BC020755 BG563083 BX509490
RefSeq transcript (Entrez)NM_003167
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SULT2A1
Cluster EST : UnigeneHs.515835 [ NCBI ]
CGAP (NCI)Hs.515835
Alternative Splicing GalleryENSG00000105398
Gene ExpressionSULT2A1 [ NCBI-GEO ]   SULT2A1 [ EBI - ARRAY_EXPRESS ]   SULT2A1 [ SEEK ]   SULT2A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SULT2A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6822
GTEX Portal (Tissue expression)SULT2A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ06520   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ06520  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ06520
Splice isoforms : SwissVarQ06520
Catalytic activity : Enzyme2.8.2.14 [ Enzyme-Expasy ]   2.8.2.142.8.2.14 [ IntEnz-EBI ]   2.8.2.14 [ BRENDA ]   2.8.2.14 [ KEGG ]   
PhosPhoSitePlusQ06520
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)SULT2A1
DMDM Disease mutations6822
Blocks (Seattle)SULT2A1
PDB (SRS)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
PDB (PDBSum)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
PDB (IMB)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
PDB (RSDB)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
Structural Biology KnowledgeBase1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
SCOP (Structural Classification of Proteins)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
CATH (Classification of proteins structures)1EFH    1J99    1OV4    2QP3    2QP4    3F3Y    4IFB   
SuperfamilyQ06520
Human Protein AtlasENSG00000105398
Peptide AtlasQ06520
HPRD00502
IPIIPI00216133   
Protein Interaction databases
DIP (DOE-UCLA)Q06520
IntAct (EBI)Q06520
FunCoupENSG00000105398
BioGRIDSULT2A1
STRING (EMBL)SULT2A1
ZODIACSULT2A1
Ontologies - Pathways
QuickGOQ06520
Ontology : AmiGOaryl sulfotransferase activity  estrone sulfotransferase activity  protein binding  cytosol  cytosol  ethanol catabolic process  digestion  sulfotransferase activity  sulfotransferase activity  steroid metabolic process  bile acid catabolic process  bile-salt sulfotransferase activity  steroid sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Ontology : EGO-EBIaryl sulfotransferase activity  estrone sulfotransferase activity  protein binding  cytosol  cytosol  ethanol catabolic process  digestion  sulfotransferase activity  sulfotransferase activity  steroid metabolic process  bile acid catabolic process  bile-salt sulfotransferase activity  steroid sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  sulfation  
Pathways : KEGGMetabolism of xenobiotics by cytochrome P450    Bile secretion    Chemical carcinogenesis   
NDEx NetworkSULT2A1
Atlas of Cancer Signalling NetworkSULT2A1
Wikipedia pathwaysSULT2A1
Orthology - Evolution
OrthoDB6822
GeneTree (enSembl)ENSG00000105398
Phylogenetic Trees/Animal Genes : TreeFamSULT2A1
HOVERGENQ06520
HOGENOMQ06520
Homologs : HomoloGeneSULT2A1
Homology/Alignments : Family Browser (UCSC)SULT2A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSULT2A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SULT2A1
dbVarSULT2A1
ClinVarSULT2A1
1000_GenomesSULT2A1 
Exome Variant ServerSULT2A1
ExAC (Exome Aggregation Consortium)SULT2A1 (select the gene name)
Genetic variants : HAPMAP6822
Genomic Variants (DGV)SULT2A1 [DGVbeta]
DECIPHERSULT2A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSULT2A1 
Mutations
ICGC Data PortalSULT2A1 
TCGA Data PortalSULT2A1 
Broad Tumor PortalSULT2A1
OASIS PortalSULT2A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSULT2A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSULT2A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SULT2A1
DgiDB (Drug Gene Interaction Database)SULT2A1
DoCM (Curated mutations)SULT2A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SULT2A1 (select a term)
intoGenSULT2A1
Cancer3DSULT2A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM125263   
Orphanet
MedgenSULT2A1
Genetic Testing Registry SULT2A1
NextProtQ06520 [Medical]
TSGene6822
GENETestsSULT2A1
Target ValidationSULT2A1
Huge Navigator SULT2A1 [HugePedia]
snp3D : Map Gene to Disease6822
BioCentury BCIQSULT2A1
ClinGenSULT2A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6822
Chemical/Pharm GKB GenePA346
Clinical trialSULT2A1
Miscellaneous
canSAR (ICR)SULT2A1 (select the gene name)
Probes
Litterature
PubMed73 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSULT2A1
EVEXSULT2A1
GoPubMedSULT2A1
iHOPSULT2A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:16:07 CEST 2017

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