Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SULT2B1 (sulfotransferase family 2B member 1)

Identity

Alias_namessulfotransferase family
Alias_symbol (synonym)HSST2
Other aliasARCI14
HGNC (Hugo) SULT2B1
LocusID (NCBI) 6820
Atlas_Id 50436
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48552172 and ends at 48599427 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CARD8 (19q13.33) / SULT2B1 (19q13.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  CARD8/SULT2B1 (19q13)


External links

Nomenclature
HGNC (Hugo)SULT2B1   11459
Cards
Entrez_Gene (NCBI)SULT2B1  6820  sulfotransferase family 2B member 1
AliasesARCI14; HSST2
GeneCards (Weizmann)SULT2B1
Ensembl hg19 (Hinxton)ENSG00000088002 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000088002 [Gene_View]  ENSG00000088002 [Sequence]  chr19:48552172-48599427 [Contig_View]  SULT2B1 [Vega]
ICGC DataPortalENSG00000088002
TCGA cBioPortalSULT2B1
AceView (NCBI)SULT2B1
Genatlas (Paris)SULT2B1
WikiGenes6820
SOURCE (Princeton)SULT2B1
Genetics Home Reference (NIH)SULT2B1
Genomic and cartography
GoldenPath hg38 (UCSC)SULT2B1  -     chr19:48552172-48599427 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SULT2B1  -     19q13.33   [Description]    (hg19-Feb_2009)
GoldenPathSULT2B1 - 19q13.33 [CytoView hg19]  SULT2B1 - 19q13.33 [CytoView hg38]
ImmunoBaseENSG00000088002
Mapping of homologs : NCBISULT2B1 [Mapview hg19]  SULT2B1 [Mapview hg38]
OMIM604125   617571   
Gene and transcription
Genbank (Entrez)AK096418 BC034694 U92314 U92315
RefSeq transcript (Entrez)NM_004605 NM_177973
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SULT2B1
Cluster EST : UnigeneHs.369331 [ NCBI ]
CGAP (NCI)Hs.369331
Alternative Splicing GalleryENSG00000088002
Gene ExpressionSULT2B1 [ NCBI-GEO ]   SULT2B1 [ EBI - ARRAY_EXPRESS ]   SULT2B1 [ SEEK ]   SULT2B1 [ MEM ]
Gene Expression Viewer (FireBrowse)SULT2B1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6820
GTEX Portal (Tissue expression)SULT2B1
Human Protein AtlasENSG00000088002-SULT2B1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00204   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00204  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00204
Splice isoforms : SwissVarO00204
Catalytic activity : Enzyme2.8.2.2 [ Enzyme-Expasy ]   2.8.2.22.8.2.2 [ IntEnz-EBI ]   2.8.2.2 [ BRENDA ]   2.8.2.2 [ KEGG ]   
PhosPhoSitePlusO00204
Domains : Interpro (EBI)P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)SULT2B1
DMDM Disease mutations6820
Blocks (Seattle)SULT2B1
PDB (RSDB)1Q1Q    1Q1Z    1Q20    1Q22   
PDB Europe1Q1Q    1Q1Z    1Q20    1Q22   
PDB (PDBSum)1Q1Q    1Q1Z    1Q20    1Q22   
PDB (IMB)1Q1Q    1Q1Z    1Q20    1Q22   
Structural Biology KnowledgeBase1Q1Q    1Q1Z    1Q20    1Q22   
SCOP (Structural Classification of Proteins)1Q1Q    1Q1Z    1Q20    1Q22   
CATH (Classification of proteins structures)1Q1Q    1Q1Z    1Q20    1Q22   
SuperfamilyO00204
Human Protein Atlas [tissue]ENSG00000088002-SULT2B1 [tissue]
Peptide AtlasO00204
HPRD04991
IPIIPI00008179   IPI00328142   
Protein Interaction databases
DIP (DOE-UCLA)O00204
IntAct (EBI)O00204
FunCoupENSG00000088002
BioGRIDSULT2B1
STRING (EMBL)SULT2B1
ZODIACSULT2B1
Ontologies - Pathways
QuickGOO00204
Ontology : AmiGOsulfate assimilation  nucleic acid binding  alcohol sulfotransferase activity  protein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  steroid metabolic process  cholesterol metabolic process  negative regulation of cell proliferation  cholesterol binding  intracellular membrane-bounded organelle  positive regulation of epidermal cell differentiation  steroid sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  extracellular exosome  steroid hormone binding  
Ontology : EGO-EBIsulfate assimilation  nucleic acid binding  alcohol sulfotransferase activity  protein binding  nucleus  cytoplasm  endoplasmic reticulum  cytosol  cytosol  steroid metabolic process  cholesterol metabolic process  negative regulation of cell proliferation  cholesterol binding  intracellular membrane-bounded organelle  positive regulation of epidermal cell differentiation  steroid sulfotransferase activity  steroid sulfotransferase activity  3'-phosphoadenosine 5'-phosphosulfate metabolic process  3'-phosphoadenosine 5'-phosphosulfate metabolic process  extracellular exosome  steroid hormone binding  
Pathways : KEGGSteroid hormone biosynthesis   
NDEx NetworkSULT2B1
Atlas of Cancer Signalling NetworkSULT2B1
Wikipedia pathwaysSULT2B1
Orthology - Evolution
OrthoDB6820
GeneTree (enSembl)ENSG00000088002
Phylogenetic Trees/Animal Genes : TreeFamSULT2B1
HOGENOMO00204
Homologs : HomoloGeneSULT2B1
Homology/Alignments : Family Browser (UCSC)SULT2B1
Gene fusions - Rearrangements
Fusion : MitelmanCARD8/SULT2B1 [19q13.33/19q13.33]  [t(19;19)(q13;q13)]  
Fusion : QuiverSULT2B1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSULT2B1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SULT2B1
dbVarSULT2B1
ClinVarSULT2B1
1000_GenomesSULT2B1 
Exome Variant ServerSULT2B1
ExAC (Exome Aggregation Consortium)ENSG00000088002
GNOMAD BrowserENSG00000088002
Varsome BrowserSULT2B1
Genetic variants : HAPMAP6820
Genomic Variants (DGV)SULT2B1 [DGVbeta]
DECIPHERSULT2B1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSULT2B1 
Mutations
ICGC Data PortalSULT2B1 
TCGA Data PortalSULT2B1 
Broad Tumor PortalSULT2B1
OASIS PortalSULT2B1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSULT2B1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSULT2B1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SULT2B1
DgiDB (Drug Gene Interaction Database)SULT2B1
DoCM (Curated mutations)SULT2B1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SULT2B1 (select a term)
intoGenSULT2B1
Cancer3DSULT2B1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604125    617571   
Orphanet
DisGeNETSULT2B1
MedgenSULT2B1
Genetic Testing Registry SULT2B1
NextProtO00204 [Medical]
TSGene6820
GENETestsSULT2B1
Target ValidationSULT2B1
Huge Navigator SULT2B1 [HugePedia]
snp3D : Map Gene to Disease6820
BioCentury BCIQSULT2B1
ClinGenSULT2B1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6820
Chemical/Pharm GKB GenePA36249
Clinical trialSULT2B1
Miscellaneous
canSAR (ICR)SULT2B1 (select the gene name)
DataMed IndexSULT2B1
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSULT2B1
EVEXSULT2B1
GoPubMedSULT2B1
iHOPSULT2B1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 7 18:18:51 CEST 2019

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.