SULT4A1 (sulfotransferase family 4A member 1)

2014-11-01  

Identity

HGNC
LOCATION
22q13.31
LOCUSID
ALIAS
BR-STL-1,BRSTL1,DJ388M5.3,NST,SULTX3,hBR-STL-1

Other Information

Locus ID:

NCBI: 25830
MIM: 608359
HGNC: 14903
Ensembl: ENSG00000130540

Variants:

dbSNP: 25830
ClinVar: 25830
TCGA: ENSG00000130540
COSMIC: SULT4A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000130540ENST00000330884Q9BR01
ENSG00000130540ENST00000422525Q9BR01
ENSG00000130540ENST00000422525A0A024R4X9
ENSG00000130540ENST00000432404F8WE22

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Biological oxidationsREACTOMER-HSA-211859
Phase II conjugationREACTOMER-HSA-156580
Cytosolic sulfonation of small moleculesREACTOMER-HSA-156584

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
208197782010MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.21
146239332003Localization of a brain sulfotransferase, SULT4A1, in the human and rat brain: an immunohistochemical study.16
188237572008Association of Sult4A1 SNPs with psychopathology and cognition in patients with schizophrenia or schizoaffective disorder.8
188237572008Association of Sult4A1 SNPs with psychopathology and cognition in patients with schizophrenia or schizoaffective disorder.8
215210202011Evidence for a SULT4A1 haplotype correlating with baseline psychopathology and atypical antipsychotic response.6
194394982009Cytosolic Aryl sulfotransferase 4A1 interacts with the peptidyl prolyl cis-trans isomerase Pin1.4
161525682005Transmission disequilibrium suggests a role for the sulfotransferase-4A1 gene in schizophrenia.3
193430462009Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.3
249884292014Expression of the orphan cytosolic sulfotransferase SULT4A1 and its major splice variant in human tissues and cells: dimerization, degradation and polyubiquitination.3
191251092009Lack of exonic sulfotransferase 4A1 mutations in controls and schizophrenia cases.2

Citation

Dessen P

SULT4A1 (sulfotransferase family 4A member 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/74369/sult4a1