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SUMO1 (small ubiquitin-like modifier 1)

Identity

Other namesDAP1
GMP1
OFC10
PIC1
SENP2
SMT3
SMT3C
SMT3H3
UBL1
HGNC (Hugo) SUMO1
LocusID (NCBI) 7341
Atlas_Id 42758
Location 2q33.1  [Link to chromosome band 2q33]
Location_base_pair Starts at 203070903 and ends at 203103322 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SPCS2 (11q13.4) / SUMO1 (2q33.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SUMO1   12502
Cards
Entrez_Gene (NCBI)SUMO1  7341  small ubiquitin-like modifier 1
AliasesDAP1; GMP1; OFC10; PIC1; 
SENP2; SMT3; SMT3C; SMT3H3; UBL1
GeneCards (Weizmann)SUMO1
Ensembl hg19 (Hinxton)ENSG00000116030 [Gene_View]  chr2:203070903-203103322 [Contig_View]  SUMO1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000116030 [Gene_View]  chr2:203070903-203103322 [Contig_View]  SUMO1 [Vega]
ICGC DataPortalENSG00000116030
TCGA cBioPortalSUMO1
AceView (NCBI)SUMO1
Genatlas (Paris)SUMO1
WikiGenes7341
SOURCE (Princeton)SUMO1
Genomic and cartography
GoldenPath hg19 (UCSC)SUMO1  -     chr2:203070903-203103322 -  2q33.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SUMO1  -     2q33.1   [Description]    (hg38-Dec_2013)
EnsemblSUMO1 - 2q33.1 [CytoView hg19]  SUMO1 - 2q33.1 [CytoView hg38]
Mapping of homologs : NCBISUMO1 [Mapview hg19]  SUMO1 [Mapview hg38]
OMIM601912   613705   
Gene and transcription
Genbank (Entrez)AA401634 AB062294 AI815216 AK311840 BC005899
RefSeq transcript (Entrez)NM_001005781 NM_001005782 NM_003352
RefSeq genomic (Entrez)NC_000002 NC_018913 NG_011679 NT_005403 NW_004929305
Consensus coding sequences : CCDS (NCBI)SUMO1
Cluster EST : UnigeneHs.81424 [ NCBI ]
CGAP (NCI)Hs.81424
Alternative Splicing GalleryENSG00000116030
Gene ExpressionSUMO1 [ NCBI-GEO ]   SUMO1 [ EBI - ARRAY_EXPRESS ]   SUMO1 [ SEEK ]   SUMO1 [ MEM ]
Gene Expression Viewer (FireBrowse)SUMO1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7341
GTEX Portal (Tissue expression)SUMO1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP63165 (Uniprot)
NextProtP63165  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP63165
Splice isoforms : SwissVarP63165 (Swissvar)
PhosPhoSitePlusP63165
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)Rad60/SUMO-like_dom    Ubiquitin-rel_dom    Ubiquitin_dom   
Domain families : Pfam (Sanger)Rad60-SLD (PF11976)   
Domain families : Pfam (NCBI)pfam11976   
Domain families : Smart (EMBL)UBQ (SM00213)  
DMDM Disease mutations7341
Blocks (Seattle)SUMO1
PDB (SRS)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
PDB (PDBSum)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
PDB (IMB)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
PDB (RSDB)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
Structural Biology KnowledgeBase1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
SCOP (Structural Classification of Proteins)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
CATH (Classification of proteins structures)1A5R    1TGZ    1WYW    1Y8R    1Z5S    2ASQ    2BF8    2G4D    2IO2    2IY0    2IY1    2KQS    2LAS    2MW5    2PE6    2UYZ    2VRR    3KYC    3KYD    3RZW    3UIP    4WJN    4WJO    4WJP    4WJQ    5AEK   
SuperfamilyP63165
Human Protein AtlasENSG00000116030
Peptide AtlasP63165
HPRD03554
IPIIPI00303105   IPI00917683   IPI00916532   IPI00917981   IPI00917832   IPI00917013   IPI00477045   
Protein Interaction databases
DIP (DOE-UCLA)P63165
IntAct (EBI)P63165
FunCoupENSG00000116030
BioGRIDSUMO1
STRING (EMBL)SUMO1
ZODIACSUMO1
Ontologies - Pathways
QuickGOP63165
Ontology : AmiGOheterochromatin  fibrillar center  XY body  protein binding  nucleus  nuclear pore  nucleoplasm  nucleolus  cytoplasm  plasma membrane  DNA repair  double-strand break repair via nonhomologous end joining  voltage-gated potassium channel complex  transcription factor binding  potassium channel regulator activity  viral process  nuclear body  PML body  PML body  nuclear speck  protein sumoylation  protein sumoylation  dendrite  PML body organization  positive regulation of protein complex assembly  protein tag  ubiquitin protein ligase binding  nuclear membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of protein localization  negative regulation of DNA binding  negative regulation of sequence-specific DNA binding transcription factor activity  ion channel binding  poly(A) RNA binding  synapse  negative regulation of action potential  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  protein stabilization  palate development  regulation of interferon-gamma-mediated signaling pathway  global genome nucleotide-excision repair  regulation of cardiac muscle cell contraction  protein localization to nuclear pore  positive regulation of calcium-transporting ATPase activity  negative regulation of delayed rectifier potassium channel activity  
Ontology : EGO-EBIheterochromatin  fibrillar center  XY body  protein binding  nucleus  nuclear pore  nucleoplasm  nucleolus  cytoplasm  plasma membrane  DNA repair  double-strand break repair via nonhomologous end joining  voltage-gated potassium channel complex  transcription factor binding  potassium channel regulator activity  viral process  nuclear body  PML body  PML body  nuclear speck  protein sumoylation  protein sumoylation  dendrite  PML body organization  positive regulation of protein complex assembly  protein tag  ubiquitin protein ligase binding  nuclear membrane  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of protein localization  negative regulation of DNA binding  negative regulation of sequence-specific DNA binding transcription factor activity  ion channel binding  poly(A) RNA binding  synapse  negative regulation of action potential  negative regulation of transcription, DNA-templated  negative regulation of transcription, DNA-templated  protein stabilization  palate development  regulation of interferon-gamma-mediated signaling pathway  global genome nucleotide-excision repair  regulation of cardiac muscle cell contraction  protein localization to nuclear pore  positive regulation of calcium-transporting ATPase activity  negative regulation of delayed rectifier potassium channel activity  
Pathways : BIOCARTARole of Parkin in the Ubiquitin-Proteasomal Pathway [Genes]    Regulation of transcriptional activity by PML [Genes]    SUMOylation as a mechanism to modulate CtBP-dependent gene responses [Genes]    Sumoylation by RanBP2 Regulates Transcriptional Repression [Genes]    Basic Mechanisms of SUMOylation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkSUMO1
Atlas of Cancer Signalling NetworkSUMO1
Wikipedia pathwaysSUMO1
Orthology - Evolution
OrthoDB7341
GeneTree (enSembl)ENSG00000116030
Phylogenetic Trees/Animal Genes : TreeFamSUMO1
Homologs : HomoloGeneSUMO1
Homology/Alignments : Family Browser (UCSC)SUMO1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSUMO1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUMO1
dbVarSUMO1
ClinVarSUMO1
1000_GenomesSUMO1 
Exome Variant ServerSUMO1
ExAC (Exome Aggregation Consortium)SUMO1 (select the gene name)
Genetic variants : HAPMAP7341
Genomic Variants (DGV)SUMO1 [DGVbeta]
Mutations
ICGC Data PortalSUMO1 
TCGA Data PortalSUMO1 
Broad Tumor PortalSUMO1
OASIS PortalSUMO1 [ Somatic mutations - Copy number]
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SUMO1
DgiDB (Drug Gene Interaction Database)SUMO1
DoCM (Curated mutations)SUMO1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUMO1 (select a term)
intoGenSUMO1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)2:203070903-203103322  ENSG00000116030
CONAN: Copy Number AnalysisSUMO1 
Mutations and Diseases : HGMDSUMO1
OMIM601912    613705   
MedgenSUMO1
Genetic Testing Registry SUMO1
NextProtP63165 [Medical]
TSGene7341
GENETestsSUMO1
Huge Navigator SUMO1 [HugePedia]
snp3D : Map Gene to Disease7341
BioCentury BCIQSUMO1
ClinGenSUMO1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7341
Chemical/Pharm GKB GenePA37149
Clinical trialSUMO1
Miscellaneous
canSAR (ICR)SUMO1 (select the gene name)
Probes
Litterature
PubMed473 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUMO1
EVEXSUMO1
GoPubMedSUMO1
iHOPSUMO1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Oct 1 16:18:06 CEST 2016

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