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SUMO2 (small ubiquitin-like modifier 2)

Identity

Alias_namesSMT3H2
SMT3 (suppressor of mif two 3, yeast) homolog 2
SMT3 suppressor of mif two 3 homolog 2 (yeast)
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
Alias_symbol (synonym)SMT3B
Other aliasHSMT3
SUMO3
Smt3A
HGNC (Hugo) SUMO2
LocusID (NCBI) 6613
Atlas_Id 51516
Location 17q25.1  [Link to chromosome band 17q25]
Location_base_pair Starts at 75167730 and ends at 75183003 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NUP85 (17q25.1) / SUMO2 (17q25.1)SUMO2 (17q25.1) / MXRA7 (17q25.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  inv(2)(p23q13) RANBP2/ALK::t(2;2)(p23;q13) RANBP2/ALK


External links

Nomenclature
HGNC (Hugo)SUMO2   11125
Cards
Entrez_Gene (NCBI)SUMO2  6613  small ubiquitin-like modifier 2
AliasesHSMT3; SMT3B; SMT3H2; SUMO3; 
Smt3A
GeneCards (Weizmann)SUMO2
Ensembl hg19 (Hinxton)ENSG00000188612 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000188612 [Gene_View]  chr17:75167730-75183003 [Contig_View]  SUMO2 [Vega]
ICGC DataPortalENSG00000188612
TCGA cBioPortalSUMO2
AceView (NCBI)SUMO2
Genatlas (Paris)SUMO2
WikiGenes6613
SOURCE (Princeton)SUMO2
Genetics Home Reference (NIH)SUMO2
Genomic and cartography
GoldenPath hg38 (UCSC)SUMO2  -     chr17:75167730-75183003 -  17q25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUMO2  -     17q25.1   [Description]    (hg19-Feb_2009)
EnsemblSUMO2 - 17q25.1 [CytoView hg19]  SUMO2 - 17q25.1 [CytoView hg38]
Mapping of homologs : NCBISUMO2 [Mapview hg19]  SUMO2 [Mapview hg38]
OMIM603042   
Gene and transcription
Genbank (Entrez)AK024823 AK225090 AK225263 AK311837 BC008450
RefSeq transcript (Entrez)NM_001005849 NM_006937
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SUMO2
Cluster EST : UnigeneHs.546298 [ NCBI ]
CGAP (NCI)Hs.546298
Alternative Splicing GalleryENSG00000188612
Gene ExpressionSUMO2 [ NCBI-GEO ]   SUMO2 [ EBI - ARRAY_EXPRESS ]   SUMO2 [ SEEK ]   SUMO2 [ MEM ]
Gene Expression Viewer (FireBrowse)SUMO2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6613
GTEX Portal (Tissue expression)SUMO2
Protein : pattern, domain, 3D structure
UniProt/SwissProtP61956   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP61956  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP61956
Splice isoforms : SwissVarP61956
PhosPhoSitePlusP61956
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)Rad60/SUMO-like_dom    Sumo    SUMO_2/3    Ubiquitin-rel_dom    Ubiquitin_dom   
Domain families : Pfam (Sanger)Rad60-SLD (PF11976)   
Domain families : Pfam (NCBI)pfam11976   
Domain families : Smart (EMBL)UBQ (SM00213)  
Conserved Domain (NCBI)SUMO2
DMDM Disease mutations6613
Blocks (Seattle)SUMO2
PDB (SRS)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
PDB (PDBSum)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
PDB (IMB)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
PDB (RSDB)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
Structural Biology KnowledgeBase1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
SCOP (Structural Classification of Proteins)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
CATH (Classification of proteins structures)1WM2    1WM3    1WZ0    1Z5Q    2AWT    2CKH    2D07    2IO0    2IO3    2IYD    2N1W    2N9E    2RPQ    3UIN    3UIO    3ZO5    4BKG    4NPN    5D2M    5ELU    5EQL   
SuperfamilyP61956
Human Protein AtlasENSG00000188612
Peptide AtlasP61956
HPRD04332
IPIIPI00299149   IPI00745893   IPI00973977   
Protein Interaction databases
DIP (DOE-UCLA)P61956
IntAct (EBI)P61956
FunCoupENSG00000188612
BioGRIDSUMO2
STRING (EMBL)SUMO2
ZODIACSUMO2
Ontologies - Pathways
QuickGOP61956
Ontology : AmiGOtranscription corepressor binding  RNA binding  protein binding  nucleus  nucleoplasm  PML body  protein sumoylation  protein sumoylation  SUMO transferase activity  protein tag  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of transcription from RNA polymerase II promoter  global genome nucleotide-excision repair  
Ontology : EGO-EBItranscription corepressor binding  RNA binding  protein binding  nucleus  nucleoplasm  PML body  protein sumoylation  protein sumoylation  SUMO transferase activity  protein tag  ubiquitin protein ligase binding  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  positive regulation of transcription from RNA polymerase II promoter  global genome nucleotide-excision repair  
Pathways : BIOCARTABasic Mechanisms of SUMOylation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkSUMO2
Atlas of Cancer Signalling NetworkSUMO2
Wikipedia pathwaysSUMO2
Orthology - Evolution
OrthoDB6613
GeneTree (enSembl)ENSG00000188612
Phylogenetic Trees/Animal Genes : TreeFamSUMO2
HOVERGENP61956
HOGENOMP61956
Homologs : HomoloGeneSUMO2
Homology/Alignments : Family Browser (UCSC)SUMO2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUMO2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUMO2
dbVarSUMO2
ClinVarSUMO2
1000_GenomesSUMO2 
Exome Variant ServerSUMO2
ExAC (Exome Aggregation Consortium)SUMO2 (select the gene name)
Genetic variants : HAPMAP6613
Genomic Variants (DGV)SUMO2 [DGVbeta]
DECIPHERSUMO2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUMO2 
Mutations
ICGC Data PortalSUMO2 
TCGA Data PortalSUMO2 
Broad Tumor PortalSUMO2
OASIS PortalSUMO2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUMO2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSUMO2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SUMO2
DgiDB (Drug Gene Interaction Database)SUMO2
DoCM (Curated mutations)SUMO2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUMO2 (select a term)
intoGenSUMO2
Cancer3DSUMO2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603042   
Orphanet
MedgenSUMO2
Genetic Testing Registry SUMO2
NextProtP61956 [Medical]
TSGene6613
GENETestsSUMO2
Target ValidationSUMO2
Huge Navigator SUMO2 [HugePedia]
snp3D : Map Gene to Disease6613
BioCentury BCIQSUMO2
ClinGenSUMO2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6613
Chemical/Pharm GKB GenePA134914683
Clinical trialSUMO2
Miscellaneous
canSAR (ICR)SUMO2 (select the gene name)
Probes
Litterature
PubMed182 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUMO2
EVEXSUMO2
GoPubMedSUMO2
iHOPSUMO2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:58:09 CEST 2017

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