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SUMO3 (small ubiquitin-like modifier 3)

Identity

Alias_namesSMT3H1
SMT3 (suppressor of mif two 3, yeast) homolog 1
SMT3 suppressor of mif two 3 homolog 3 (yeast)
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
Alias_symbol (synonym)SMT3A
Other aliasSUMO-3
Smt3B
HGNC (Hugo) SUMO3
LocusID (NCBI) 6612
Atlas_Id 51514
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 44805617 and ends at 44818129 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL1A1 (17q21.33) / SUMO3 (21q22.3)FTL (19q13.33) / SUMO3 (21q22.3)SFPQ (16q24.1) / SUMO3 (21q22.3)
SUMO3 (21q22.3) / SUMO3 (21q22.3)SUMO3 (21q22.3) / UBE2G2 (21q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SUMO3   11124
Cards
Entrez_Gene (NCBI)SUMO3  6612  small ubiquitin-like modifier 3
AliasesSMT3A; SMT3H1; SUMO-3; Smt3B
GeneCards (Weizmann)SUMO3
Ensembl hg19 (Hinxton)ENSG00000184900 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184900 [Gene_View]  chr21:44805617-44818129 [Contig_View]  SUMO3 [Vega]
ICGC DataPortalENSG00000184900
TCGA cBioPortalSUMO3
AceView (NCBI)SUMO3
Genatlas (Paris)SUMO3
WikiGenes6612
SOURCE (Princeton)SUMO3
Genetics Home Reference (NIH)SUMO3
Genomic and cartography
GoldenPath hg38 (UCSC)SUMO3  -     chr21:44805617-44818129 -  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUMO3  -     21q22.3   [Description]    (hg19-Feb_2009)
EnsemblSUMO3 - 21q22.3 [CytoView hg19]  SUMO3 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBISUMO3 [Mapview hg19]  SUMO3 [Mapview hg38]
OMIM602231   
Gene and transcription
Genbank (Entrez)AK222591 AK300822 AK312350 BC000036 BC008420
RefSeq transcript (Entrez)NM_001286416 NM_006936
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SUMO3
Cluster EST : UnigeneHs.474005 [ NCBI ]
CGAP (NCI)Hs.474005
Alternative Splicing GalleryENSG00000184900
Gene ExpressionSUMO3 [ NCBI-GEO ]   SUMO3 [ EBI - ARRAY_EXPRESS ]   SUMO3 [ SEEK ]   SUMO3 [ MEM ]
Gene Expression Viewer (FireBrowse)SUMO3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6612
GTEX Portal (Tissue expression)SUMO3
Protein : pattern, domain, 3D structure
UniProt/SwissProtP55854   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP55854  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP55854
Splice isoforms : SwissVarP55854
PhosPhoSitePlusP55854
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)Rad60/SUMO-like_dom    Sumo    SUMO_2/3    Ubiquitin-rel_dom    Ubiquitin_dom   
Domain families : Pfam (Sanger)Rad60-SLD (PF11976)   
Domain families : Pfam (NCBI)pfam11976   
Domain families : Smart (EMBL)UBQ (SM00213)  
Conserved Domain (NCBI)SUMO3
DMDM Disease mutations6612
Blocks (Seattle)SUMO3
PDB (SRS)1U4A    2IO1    2MP2   
PDB (PDBSum)1U4A    2IO1    2MP2   
PDB (IMB)1U4A    2IO1    2MP2   
PDB (RSDB)1U4A    2IO1    2MP2   
Structural Biology KnowledgeBase1U4A    2IO1    2MP2   
SCOP (Structural Classification of Proteins)1U4A    2IO1    2MP2   
CATH (Classification of proteins structures)1U4A    2IO1    2MP2   
SuperfamilyP55854
Human Protein AtlasENSG00000184900
Peptide AtlasP55854
HPRD03754
IPIIPI00299147   IPI00909492   IPI00793687   IPI00798011   IPI00916998   IPI00916866   
Protein Interaction databases
DIP (DOE-UCLA)P55854
IntAct (EBI)P55854
FunCoupENSG00000184900
BioGRIDSUMO3
STRING (EMBL)SUMO3
ZODIACSUMO3
Ontologies - Pathways
QuickGOP55854
Ontology : AmiGOkinetochore  protein binding  nucleus  nucleoplasm  cytoplasm  PML body  protein sumoylation  protein sumoylation  enzyme binding  protein tag  negative regulation of DNA binding  extracellular exosome  global genome nucleotide-excision repair  
Ontology : EGO-EBIkinetochore  protein binding  nucleus  nucleoplasm  cytoplasm  PML body  protein sumoylation  protein sumoylation  enzyme binding  protein tag  negative regulation of DNA binding  extracellular exosome  global genome nucleotide-excision repair  
Pathways : BIOCARTABasic Mechanisms of SUMOylation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkSUMO3
Atlas of Cancer Signalling NetworkSUMO3
Wikipedia pathwaysSUMO3
Orthology - Evolution
OrthoDB6612
GeneTree (enSembl)ENSG00000184900
Phylogenetic Trees/Animal Genes : TreeFamSUMO3
HOVERGENP55854
HOGENOMP55854
Homologs : HomoloGeneSUMO3
Homology/Alignments : Family Browser (UCSC)SUMO3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUMO3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUMO3
dbVarSUMO3
ClinVarSUMO3
1000_GenomesSUMO3 
Exome Variant ServerSUMO3
ExAC (Exome Aggregation Consortium)SUMO3 (select the gene name)
Genetic variants : HAPMAP6612
Genomic Variants (DGV)SUMO3 [DGVbeta]
DECIPHERSUMO3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUMO3 
Mutations
ICGC Data PortalSUMO3 
TCGA Data PortalSUMO3 
Broad Tumor PortalSUMO3
OASIS PortalSUMO3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUMO3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSUMO3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SUMO3
DgiDB (Drug Gene Interaction Database)SUMO3
DoCM (Curated mutations)SUMO3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUMO3 (select a term)
intoGenSUMO3
Cancer3DSUMO3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602231   
Orphanet
MedgenSUMO3
Genetic Testing Registry SUMO3
NextProtP55854 [Medical]
TSGene6612
GENETestsSUMO3
Target ValidationSUMO3
Huge Navigator SUMO3 [HugePedia]
snp3D : Map Gene to Disease6612
BioCentury BCIQSUMO3
ClinGenSUMO3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6612
Chemical/Pharm GKB GenePA35973
Clinical trialSUMO3
Miscellaneous
canSAR (ICR)SUMO3 (select the gene name)
Probes
Litterature
PubMed115 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUMO3
EVEXSUMO3
GoPubMedSUMO3
iHOPSUMO3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:58:09 CEST 2017

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