Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SUN1 (Sad1 and UNC84 domain containing 1)

Identity

Alias_namesUNC84A
unc-84 homolog A (C. elegans)
Alias_symbol (synonym)KIAA0810
FLJ12407
Other alias
HGNC (Hugo) SUN1
LocusID (NCBI) 23353
Atlas_Id 56534
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 816615 and ends at 874920 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADAP1 (7p22.3) / SUN1 (7p22.3)NUPL2 (7p15.3) / SUN1 (7p22.3)SUN1 (7p22.3) / ICA1 (7p21.3)
SUN1 (7p22.3) / KRT5 (12q13.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;7)(p21;p22) SUN1/ICA1

External links

Nomenclature
HGNC (Hugo)SUN1   18587
Cards
Entrez_Gene (NCBI)SUN1  23353  Sad1 and UNC84 domain containing 1
AliasesUNC84A
GeneCards (Weizmann)SUN1
Ensembl hg19 (Hinxton)ENSG00000164828 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164828 [Gene_View]  ENSG00000164828 [Sequence]  chr7:816615-874920 [Contig_View]  SUN1 [Vega]
ICGC DataPortalENSG00000164828
TCGA cBioPortalSUN1
AceView (NCBI)SUN1
Genatlas (Paris)SUN1
WikiGenes23353
SOURCE (Princeton)SUN1
Genetics Home Reference (NIH)SUN1
Genomic and cartography
GoldenPath hg38 (UCSC)SUN1  -     chr7:816615-874920 +  21q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SUN1  -     21q22.3   [Description]    (hg19-Feb_2009)
EnsemblSUN1 - 21q22.3 [CytoView hg19]  SUN1 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBISUN1 [Mapview hg19]  SUN1 [Mapview hg38]
OMIM607723   
Gene and transcription
Genbank (Entrez)AB018353 AB648918 AF202724 AK022469 AK022816
RefSeq transcript (Entrez)NM_001130965 NM_001171944 NM_001171945 NM_001171946 NM_025154
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SUN1
Cluster EST : UnigeneHs.438072 [ NCBI ]
CGAP (NCI)Hs.438072
Alternative Splicing GalleryENSG00000164828
Gene ExpressionSUN1 [ NCBI-GEO ]   SUN1 [ EBI - ARRAY_EXPRESS ]   SUN1 [ SEEK ]   SUN1 [ MEM ]
Gene Expression Viewer (FireBrowse)SUN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23353
GTEX Portal (Tissue expression)SUN1
Human Protein AtlasENSG00000164828-SUN1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO94901   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO94901  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO94901
Splice isoforms : SwissVarO94901
PhosPhoSitePlusO94901
Domaine pattern : Prosite (Expaxy)SUN (PS51469)   
Domains : Interpro (EBI)Galactose-bd-like_sf    SUN1    SUN1_N    SUN_dom   
Domain families : Pfam (Sanger)MRP (PF09387)    Sad1_UNC (PF07738)   
Domain families : Pfam (NCBI)pfam09387    pfam07738   
Conserved Domain (NCBI)SUN1
DMDM Disease mutations23353
Blocks (Seattle)SUN1
SuperfamilyO94901
Human Protein Atlas [tissue]ENSG00000164828-SUN1 [tissue]
Peptide AtlasO94901
HPRD16257
IPIIPI00335367   IPI00306682   IPI00873723   IPI00844303   IPI00892866   IPI00894044   IPI00955411   IPI00977594   IPI00783943   IPI00893282   IPI00894370   IPI00894501   IPI00894185   IPI00409738   IPI00893631   IPI00847194   
Protein Interaction databases
DIP (DOE-UCLA)O94901
IntAct (EBI)O94901
FunCoupENSG00000164828
BioGRIDSUN1
STRING (EMBL)SUN1
ZODIACSUN1
Ontologies - Pathways
QuickGOO94901
Ontology : AmiGOossification  acrosomal membrane  protein binding  lamin binding  nuclear envelope  nuclear envelope  nuclear envelope  integral component of nuclear inner membrane  nuclear envelope organization  nuclear envelope organization  synapsis  spermatogenesis  response to mechanical stimulus  nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration  nuclear membrane  meiotic nuclear membrane microtubule tethering complex  intracellular membrane-bounded organelle  protein membrane anchor  centrosome localization  meiotic attachment of telomere to nuclear envelope  cytoskeletal anchoring at nuclear membrane  cytoskeletal anchoring at nuclear membrane  nuclear matrix anchoring at nuclear membrane  
Ontology : EGO-EBIossification  acrosomal membrane  protein binding  lamin binding  nuclear envelope  nuclear envelope  nuclear envelope  integral component of nuclear inner membrane  nuclear envelope organization  nuclear envelope organization  synapsis  spermatogenesis  response to mechanical stimulus  nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration  nuclear membrane  meiotic nuclear membrane microtubule tethering complex  intracellular membrane-bounded organelle  protein membrane anchor  centrosome localization  meiotic attachment of telomere to nuclear envelope  cytoskeletal anchoring at nuclear membrane  cytoskeletal anchoring at nuclear membrane  nuclear matrix anchoring at nuclear membrane  
NDEx NetworkSUN1
Atlas of Cancer Signalling NetworkSUN1
Wikipedia pathwaysSUN1
Orthology - Evolution
OrthoDB23353
GeneTree (enSembl)ENSG00000164828
Phylogenetic Trees/Animal Genes : TreeFamSUN1
HOVERGENO94901
HOGENOMO94901
Homologs : HomoloGeneSUN1
Homology/Alignments : Family Browser (UCSC)SUN1
Gene fusions - Rearrangements
Fusion : QuiverSUN1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSUN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUN1
dbVarSUN1
ClinVarSUN1
1000_GenomesSUN1 
Exome Variant ServerSUN1
ExAC (Exome Aggregation Consortium)ENSG00000164828
GNOMAD BrowserENSG00000164828
Varsome BrowserSUN1
Genetic variants : HAPMAP23353
Genomic Variants (DGV)SUN1 [DGVbeta]
DECIPHERSUN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSUN1 
Mutations
ICGC Data PortalSUN1 
TCGA Data PortalSUN1 
Broad Tumor PortalSUN1
OASIS PortalSUN1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSUN1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSUN1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SUN1
DgiDB (Drug Gene Interaction Database)SUN1
DoCM (Curated mutations)SUN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUN1 (select a term)
intoGenSUN1
Cancer3DSUN1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607723   
Orphanet
DisGeNETSUN1
MedgenSUN1
Genetic Testing Registry SUN1
NextProtO94901 [Medical]
TSGene23353
GENETestsSUN1
Target ValidationSUN1
Huge Navigator SUN1 [HugePedia]
snp3D : Map Gene to Disease23353
BioCentury BCIQSUN1
ClinGenSUN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23353
Chemical/Pharm GKB GenePA165618311
Clinical trialSUN1
Miscellaneous
canSAR (ICR)SUN1 (select the gene name)
Probes
Litterature
PubMed53 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUN1
EVEXSUN1
GoPubMedSUN1
iHOPSUN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 30 15:18:06 CEST 2018
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