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SUPT3H (SPT3 homolog, SAGA and STAGA complex component)

Identity

Other namesSPT3
SPT3L
HGNC (Hugo) SUPT3H
LocusID (NCBI) 8464
Atlas_Id 42451
Location 6p21.1
Location_base_pair Starts at 44794467 and ends at 45345788 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2015)
CD2AP 6p12.3 / SUPT3H 6p21.1EXOC4 7q33 / SUPT3H 6p21.1LRRC1 6p12.1 / SUPT3H 6p21.1
MUT 6p12.3 / SUPT3H 6p21.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SUPT3H   11466
Cards
Entrez_Gene (NCBI)SUPT3H  8464  SPT3 homolog, SAGA and STAGA complex component
GeneCards (Weizmann)SUPT3H
Ensembl hg19 (Hinxton)ENSG00000196284 [Gene_View]  chr6:44794467-45345788 [Contig_View]  SUPT3H [Vega]
Ensembl hg38 (Hinxton)ENSG00000196284 [Gene_View]  chr6:44794467-45345788 [Contig_View]  SUPT3H [Vega]
ICGC DataPortalENSG00000196284
TCGA cBioPortalSUPT3H
AceView (NCBI)SUPT3H
Genatlas (Paris)SUPT3H
WikiGenes8464
SOURCE (Princeton)SUPT3H
Genomic and cartography
GoldenPath hg19 (UCSC)SUPT3H  -     chr6:44794467-45345788 -  6p21.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SUPT3H  -     6p21.1   [Description]    (hg38-Dec_2013)
EnsemblSUPT3H - 6p21.1 [CytoView hg19]  SUPT3H - 6p21.1 [CytoView hg38]
Mapping of homologs : NCBISUPT3H [Mapview hg19]  SUPT3H [Mapview hg38]
OMIM602947   
Gene and transcription
Genbank (Entrez)AF069734 AF073930 AF279781 AK092340 AK303838
RefSeq transcript (Entrez)NM_001261823 NM_003599 NM_181356
RefSeq genomic (Entrez)NC_000006 NC_018917 NT_007592 NW_004929326
Consensus coding sequences : CCDS (NCBI)SUPT3H
Cluster EST : UnigeneHs.368325 [ NCBI ]
CGAP (NCI)Hs.368325
Alternative Splicing : Fast-db (Paris)GSHG0026648
Alternative Splicing GalleryENSG00000196284
Gene ExpressionSUPT3H [ NCBI-GEO ]     SUPT3H [ SEEK ]   SUPT3H [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)8464
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75486 (Uniprot)
NextProtO75486  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75486
Splice isoforms : SwissVarO75486 (Swissvar)
PhosPhoSitePlusO75486
Domains : Interpro (EBI)Histone-fold    TFIID-18   
Domain families : Pfam (Sanger)TFIID-18kDa (PF02269)   
Domain families : Pfam (NCBI)pfam02269   
DMDM Disease mutations8464
Blocks (Seattle)SUPT3H
Human Protein AtlasENSG00000196284
Peptide AtlasO75486
HPRD04254
IPIIPI00025792   IPI00303875   IPI00384341   IPI00478264   
Protein Interaction databases
DIP (DOE-UCLA)O75486
IntAct (EBI)O75486
FunCoupENSG00000196284
BioGRIDSUPT3H
IntegromeDBSUPT3H
STRING (EMBL)SUPT3H
ZODIACSUPT3H
Ontologies - Pathways
QuickGOO75486
Ontology : AmiGOSAGA complex  positive regulation of defense response to virus by host  DNA binding  transcription coactivator activity  histone acetyltransferase activity  nucleus  nucleoplasm  transcription factor TFIID complex  chromatin organization  regulation of transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  histone deubiquitination  STAGA complex  transcription factor TFTC complex  histone H3 acetylation  positive regulation of transcription, DNA-templated  protein heterodimerization activity  mitophagy in response to mitochondrial depolarization  xenophagy  
Ontology : EGO-EBISAGA complex  positive regulation of defense response to virus by host  DNA binding  transcription coactivator activity  histone acetyltransferase activity  nucleus  nucleoplasm  transcription factor TFIID complex  chromatin organization  regulation of transcription, DNA-templated  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  histone deubiquitination  STAGA complex  transcription factor TFTC complex  histone H3 acetylation  positive regulation of transcription, DNA-templated  protein heterodimerization activity  mitophagy in response to mitochondrial depolarization  xenophagy  
Pathways : KEGGTranscriptional misregulation in cancer   
Protein Interaction DatabaseSUPT3H
Atlas of Cancer Signalling NetworkSUPT3H
Wikipedia pathwaysSUPT3H
Orthology - Evolution
OrthoDB8464
GeneTree (enSembl)ENSG00000196284
Phylogenetic Trees/Animal Genes : TreeFamSUPT3H
Homologs : HomoloGeneSUPT3H
Homology/Alignments : Family Browser (UCSC)SUPT3H
Gene fusions - Rearrangements
Fusion: TCGACD2AP 6p12.3 SUPT3H 6p21.1 LUAD
Fusion: TCGAEXOC4 7q33 SUPT3H 6p21.1 LUAD
Fusion: TCGALRRC1 6p12.1 SUPT3H 6p21.1 LGG
Fusion: TCGAMUT 6p12.3 SUPT3H 6p21.1 LUAD
Polymorphisms : SNP, variants
NCBI Variation ViewerSUPT3H [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SUPT3H
dbVarSUPT3H
ClinVarSUPT3H
1000_GenomesSUPT3H 
Exome Variant ServerSUPT3H
Exome Aggregation Consortium (ExAC)ENSG00000196284
SNP (GeneSNP Utah)SUPT3H
SNP : HGBaseSUPT3H
Genetic variants : HAPMAPSUPT3H
Genomic Variants (DGV)SUPT3H [DGVbeta]
Mutations
ICGC Data PortalSUPT3H 
TCGA Data PortalSUPT3H 
Tumor PortalSUPT3H
TCGA Copy Number PortalSUPT3H
Somatic Mutations in Cancer : COSMICSUPT3H 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SUPT3H
DgiDB (Drug Gene Interaction Database)SUPT3H
DoCM (Curated mutations)SUPT3H (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SUPT3H (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)6:44794467-45345788
CONAN: Copy Number AnalysisSUPT3H 
Mutations and Diseases : HGMDSUPT3H
OMIM602947   
MedgenSUPT3H
NextProtO75486 [Medical]
TSGene8464
GENETestsSUPT3H
Huge Navigator SUPT3H [HugePedia]  SUPT3H [HugeCancerGEM]
snp3D : Map Gene to Disease8464
BioCentury BCIQSUPT3H
General knowledge
Chemical/Protein Interactions : CTD8464
Chemical/Pharm GKB GenePA36252
Clinical trialSUPT3H
Other databases
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSUPT3H
GoPubMedSUPT3H
iHOPSUPT3H
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jan 16 19:35:18 CET 2016

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