Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SYAP1 (synapse associated protein 1)

Identity

Alias_symbol (synonym)FLJ14495
PRO3113
Other aliasBSTA
HGNC (Hugo) SYAP1
LocusID (NCBI) 94056
Atlas_Id 54679
Location Xp22.2  [Link to chromosome band Xp22]
Location_base_pair Starts at 16719584 and ends at 16762684 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ABCA2 (9q34.3) / SYAP1 (Xp22.2)SYAP1 (Xp22.2) / CPD (17q11.2)SYAP1 (Xp22.2) / SLC5A5 (19p13.11)
TXLNG (Xp22.2) / SYAP1 (Xp22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  TXLNG/SYAP1 (Xp22)


External links

Nomenclature
HGNC (Hugo)SYAP1   16273
Cards
Entrez_Gene (NCBI)SYAP1  94056  synapse associated protein 1
AliasesBSTA; PRO3113
GeneCards (Weizmann)SYAP1
Ensembl hg19 (Hinxton)ENSG00000169895 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169895 [Gene_View]  ENSG00000169895 [Sequence]  chrX:16719584-16762684 [Contig_View]  SYAP1 [Vega]
ICGC DataPortalENSG00000169895
TCGA cBioPortalSYAP1
AceView (NCBI)SYAP1
Genatlas (Paris)SYAP1
WikiGenes94056
SOURCE (Princeton)SYAP1
Genetics Home Reference (NIH)SYAP1
Genomic and cartography
GoldenPath hg38 (UCSC)SYAP1  -     chrX:16719584-16762684 +  Xp22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYAP1  -     Xp22.2   [Description]    (hg19-Feb_2009)
EnsemblSYAP1 - Xp22.2 [CytoView hg19]  SYAP1 - Xp22.2 [CytoView hg38]
Mapping of homologs : NCBISYAP1 [Mapview hg19]  SYAP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA829759 AF168955 AF305828 AF338728 AK027401
RefSeq transcript (Entrez)NM_032796
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SYAP1
Cluster EST : UnigeneHs.744256 [ NCBI ]
CGAP (NCI)Hs.744256
Alternative Splicing GalleryENSG00000169895
Gene ExpressionSYAP1 [ NCBI-GEO ]   SYAP1 [ EBI - ARRAY_EXPRESS ]   SYAP1 [ SEEK ]   SYAP1 [ MEM ]
Gene Expression Viewer (FireBrowse)SYAP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)94056
GTEX Portal (Tissue expression)SYAP1
Human Protein AtlasENSG00000169895-SYAP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96A49   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96A49  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96A49
Splice isoforms : SwissVarQ96A49
PhosPhoSitePlusQ96A49
Domaine pattern : Prosite (Expaxy)BSD (PS50858)   
Domains : Interpro (EBI)BSD_dom    BSD_dom_sf   
Domain families : Pfam (Sanger)BSD (PF03909)   
Domain families : Pfam (NCBI)pfam03909   
Domain families : Smart (EMBL)BSD (SM00751)  
Conserved Domain (NCBI)SYAP1
DMDM Disease mutations94056
Blocks (Seattle)SYAP1
PDB (SRS)1X3A   
PDB (PDBSum)1X3A   
PDB (IMB)1X3A   
PDB (RSDB)1X3A   
Structural Biology KnowledgeBase1X3A   
SCOP (Structural Classification of Proteins)1X3A   
CATH (Classification of proteins structures)1X3A   
SuperfamilyQ96A49
Human Protein Atlas [tissue]ENSG00000169895-SYAP1 [tissue]
Peptide AtlasQ96A49
HPRD06733
IPIIPI00059242   
Protein Interaction databases
DIP (DOE-UCLA)Q96A49
IntAct (EBI)Q96A49
FunCoupENSG00000169895
BioGRIDSYAP1
STRING (EMBL)SYAP1
ZODIACSYAP1
Ontologies - Pathways
QuickGOQ96A49
Ontology : AmiGOprotein binding  nucleoplasm  Golgi apparatus  cytosol  cell junction  cell differentiation  axon  dendrite  growth cone  extrinsic component of cytoplasmic side of plasma membrane  cellular response to insulin stimulus  cellular response to platelet-derived growth factor stimulus  TORC2 signaling  presynaptic membrane  perikaryon  postsynaptic membrane  positive regulation of fat cell differentiation  perinuclear region of cytoplasm  extracellular exosome  cellular response to epidermal growth factor stimulus  positive regulation of protein serine/threonine kinase activity  positive regulation of protein homodimerization activity  cellular response to insulin-like growth factor stimulus  
Ontology : EGO-EBIprotein binding  nucleoplasm  Golgi apparatus  cytosol  cell junction  cell differentiation  axon  dendrite  growth cone  extrinsic component of cytoplasmic side of plasma membrane  cellular response to insulin stimulus  cellular response to platelet-derived growth factor stimulus  TORC2 signaling  presynaptic membrane  perikaryon  postsynaptic membrane  positive regulation of fat cell differentiation  perinuclear region of cytoplasm  extracellular exosome  cellular response to epidermal growth factor stimulus  positive regulation of protein serine/threonine kinase activity  positive regulation of protein homodimerization activity  cellular response to insulin-like growth factor stimulus  
NDEx NetworkSYAP1
Atlas of Cancer Signalling NetworkSYAP1
Wikipedia pathwaysSYAP1
Orthology - Evolution
OrthoDB94056
GeneTree (enSembl)ENSG00000169895
Phylogenetic Trees/Animal Genes : TreeFamSYAP1
HOVERGENQ96A49
HOGENOMQ96A49
Homologs : HomoloGeneSYAP1
Homology/Alignments : Family Browser (UCSC)SYAP1
Gene fusions - Rearrangements
Fusion : MitelmanTXLNG/SYAP1 [Xp22.2/Xp22.2]  [t(X;X)(p22;p22)]  
Fusion : QuiverSYAP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYAP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYAP1
dbVarSYAP1
ClinVarSYAP1
1000_GenomesSYAP1 
Exome Variant ServerSYAP1
ExAC (Exome Aggregation Consortium)ENSG00000169895
GNOMAD BrowserENSG00000169895
Varsome BrowserSYAP1
Genetic variants : HAPMAP94056
Genomic Variants (DGV)SYAP1 [DGVbeta]
DECIPHERSYAP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYAP1 
Mutations
ICGC Data PortalSYAP1 
TCGA Data PortalSYAP1 
Broad Tumor PortalSYAP1
OASIS PortalSYAP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYAP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSYAP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SYAP1
DgiDB (Drug Gene Interaction Database)SYAP1
DoCM (Curated mutations)SYAP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYAP1 (select a term)
intoGenSYAP1
Cancer3DSYAP1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSYAP1
MedgenSYAP1
Genetic Testing Registry SYAP1
NextProtQ96A49 [Medical]
TSGene94056
GENETestsSYAP1
Target ValidationSYAP1
Huge Navigator SYAP1 [HugePedia]
snp3D : Map Gene to Disease94056
BioCentury BCIQSYAP1
ClinGenSYAP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD94056
Chemical/Pharm GKB GenePA38107
Clinical trialSYAP1
Miscellaneous
canSAR (ICR)SYAP1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYAP1
EVEXSYAP1
GoPubMedSYAP1
iHOPSYAP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Aug 27 11:55:57 CEST 2018

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