SYCP2 (synaptonemal complex protein 2)

2016-08-01  

Identity

HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
SCP-2,SCP2,SPGF1
FUSION GENES

Other Information

Locus ID:

NCBI: 10388
MIM: 604105
HGNC: 11490
Ensembl: ENSG00000196074

Variants:

dbSNP: 10388
ClinVar: 10388
TCGA: ENSG00000196074
COSMIC: SYCP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196074ENST00000357552Q9BX26
ENSG00000196074ENST00000371001Q9BX26
ENSG00000196074ENST00000412613A2A340
ENSG00000196074ENST00000425931A2A2M9
ENSG00000196074ENST00000446834A2A341

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
MeiosisREACTOMER-HSA-1500620
Meiotic synapsisREACTOMER-HSA-1221632

References

Pubmed IDYearTitleCitations
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.40
263346522015Deregulation of SYCP2 predicts early stage human papillomavirus-positive oropharyngeal carcinoma: A prospective whole transcriptome analysis.11
318660472020SYCP2 Translocation-Mediated Dysregulation and Frameshift Variants Cause Human Male Infertility.2

Citation

Dessen P

SYCP2 (synaptonemal complex protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55846/sycp2