Identity
HGNC
LOCATION
Xp11.3
LOCUSID
ALIAS
EPILX,MRX50,SYN1a,SYN1b,SYNI
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6853
MIM: 313440
HGNC: 11494
Ensembl: ENSG00000008056
Variants:
dbSNP: 6853
ClinVar: 6853
TCGA: ENSG00000008056
COSMIC: SYN1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000008056 | ENST00000295987 | P17600 |
| ENSG00000008056 | ENST00000340666 | P17600 |
| ENSG00000008056 | ENST00000639776 | A0A1W2PS00 |
| ENSG00000008056 | ENST00000640721 | A0A1W2PSE9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36693418 | 2023 | Novel SYN1 Variant in Two Brothers with Focal Epilepsy and Their Prompt Response to Valproate. | 0 |
| 36693418 | 2023 | Novel SYN1 Variant in Two Brothers with Focal Epilepsy and Their Prompt Response to Valproate. | 0 |
| 35876881 | 2022 | An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. | 13 |
| 35876881 | 2022 | An interaction between synapsin and C9orf72 regulates excitatory synapses and is impaired in ALS/FTD. | 13 |
| 33431828 | 2021 | Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells. | 30 |
| 33774037 | 2021 | Synapsin Condensates Recruit alpha-Synuclein. | 36 |
| 34243774 | 2021 | Familial SYN1 variants related neurodevelopmental disorders in Asian pediatric patients. | 4 |
| 33431828 | 2021 | Cooperative function of synaptophysin and synapsin in the generation of synaptic vesicle-like clusters in non-neuronal cells. | 30 |
| 33774037 | 2021 | Synapsin Condensates Recruit alpha-Synuclein. | 36 |
| 34243774 | 2021 | Familial SYN1 variants related neurodevelopmental disorders in Asian pediatric patients. | 4 |
| 32934297 | 2020 | Semaphorin 3A controls enteric neuron connectivity and is inversely associated with synapsin 1 expression in Hirschsprung disease. | 6 |
| 32934297 | 2020 | Semaphorin 3A controls enteric neuron connectivity and is inversely associated with synapsin 1 expression in Hirschsprung disease. | 6 |
| 31727880 | 2019 | Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function. | 17 |
| 31727880 | 2019 | Autoantibodies to synapsin I sequestrate synapsin I and alter synaptic function. | 17 |
| 29671924 | 2018 | Effects of SYN1(Q555X) mutation on cortical gray matter microstructure. | 3 |
Citation
Dessen P
SYN1 (synapsin I)
Atlas Genet Cytogenet Oncol Haematol. 2010-11-01
Online version: http://atlasgeneticsoncology.org/gene/51752/syn1
