SYN3 (synapsin III)

2007-12-01  

Identity

HGNC
LOCATION
22q12.3
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 8224
MIM: 602705
HGNC: 11496
Ensembl: ENSG00000185666

Variants:

dbSNP: 8224
ClinVar: 8224
TCGA: ENSG00000185666
COSMIC: SYN3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185666ENST00000332840A0A0A0MR68
ENSG00000185666ENST00000358763O14994
ENSG00000185666ENST00000358763A0A024R1I8
ENSG00000185666ENST00000412575Q4TT46
ENSG00000185666ENST00000441821A6ZJ82
ENSG00000185666ENST00000619146A0A087WTG8

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Neuronal SystemREACTOMER-HSA-112316
Transmission across Chemical SynapsesREACTOMER-HSA-112315
Neurotransmitter Release CycleREACTOMER-HSA-112310
Serotonin Neurotransmitter Release CycleREACTOMER-HSA-181429
Dopamine Neurotransmitter Release CycleREACTOMER-HSA-212676

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
185839792008Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.395
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
204710302010Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia.42
259675502015α-synuclein and synapsin III cooperatively regulate synaptic function in dopamine neurons.35
147325902004A rare polymorphism affects a mitogen-activated protein kinase site in synapsin III: possible relationship to schizophrenia.18
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.18
206770142010An approach based on a genome-wide association study reveals candidate loci for narcolepsy.16
159002272005Association of schizophrenia in African Americans to polymorphism in synapsin III gene.12
159002272005Association of schizophrenia in African Americans to polymorphism in synapsin III gene.12

Citation

Dessen P

SYN3 (synapsin III)

Atlas Genet Cytogenet Oncol Haematol. 2007-12-01

Online version: http://atlasgeneticsoncology.org/gene/49902/syn3