SYNGR1 (synaptogyrin 1)

2017-08-01  

Identity

HGNC
SYNGR1
LOCATION
22q13.1
LOCUSID
9145
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9145
MIM: 603925
HGNC: 11498
Ensembl: ENSG00000100321

Variants:

dbSNP: 9145
ClinVar: 9145
TCGA: ENSG00000100321
COSMIC: SYNGR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100321ENST00000216155A2A283
ENSG00000100321ENST00000318801O43759
ENSG00000100321ENST00000328933O43759
ENSG00000100321ENST00000381535O43759
ENSG00000100321ENST00000406293B5MCD7
ENSG00000100321ENST00000415332F8WCE4

Expression (GTEx)

0
50
100
150
200
250
300
350
400
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
226755292012Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1.10
162156432005SYNGR1 is associated with schizophrenia and bipolar disorder in southern India.9
162156432005SYNGR1 is associated with schizophrenia and bipolar disorder in southern India.9
196414782009Association study and mutational screening of SYNGR1 as a candidate susceptibility gene for schizophrenia.6
196414782009Association study and mutational screening of SYNGR1 as a candidate susceptibility gene for schizophrenia.6
147326012004A nonsense mutation in the synaptogyrin 1 gene in a family with schizophrenia.5
170495582007Identification of rare mutations of synaptogyrin 1 gene in patients with schizophrenia.3
196658062009No association between bipolar disorder and syngr1 or synapsin II polymorphisms in the Han Chinese population.1
196658062009No association between bipolar disorder and syngr1 or synapsin II polymorphisms in the Han Chinese population.1

Citation

Dessen P

SYNGR1 (synaptogyrin 1)

Atlas Genet Cytogenet Oncol Haematol. 2017-08-01

Online version: http://atlasgeneticsoncology.org/gene/57029/syngr1