Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SYNPO2L (synaptopodin 2 like)

Identity

Alias_namessynaptopodin 2-like
Alias_symbol (synonym)FLJ12921
Other alias-
HGNC (Hugo) SYNPO2L
LocusID (NCBI) 79933
Atlas_Id 74422
Location 10q22.2  [Link to chromosome band 10q22]
Location_base_pair Starts at 73644881 and ends at 73656105 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ERBIN (5q12.3) / SYNPO2L (10q22.2)SYNPO2L (10q22.2) / MYOZ1 (10q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SYNPO2L   23532
Cards
Entrez_Gene (NCBI)SYNPO2L  79933  synaptopodin 2 like
Aliases
GeneCards (Weizmann)SYNPO2L
Ensembl hg19 (Hinxton)ENSG00000166317 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166317 [Gene_View]  ENSG00000166317 [Sequence]  chr10:73644881-73656105 [Contig_View]  SYNPO2L [Vega]
ICGC DataPortalENSG00000166317
TCGA cBioPortalSYNPO2L
AceView (NCBI)SYNPO2L
Genatlas (Paris)SYNPO2L
WikiGenes79933
SOURCE (Princeton)SYNPO2L
Genetics Home Reference (NIH)SYNPO2L
Genomic and cartography
GoldenPath hg38 (UCSC)SYNPO2L  -     chr10:73644881-73656105 -  10q22.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYNPO2L  -     10q22.2   [Description]    (hg19-Feb_2009)
GoldenPathSYNPO2L - 10q22.2 [CytoView hg19]  SYNPO2L - 10q22.2 [CytoView hg38]
ImmunoBaseENSG00000166317
Mapping of homologs : NCBISYNPO2L [Mapview hg19]  SYNPO2L [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA176924 AB188489 AK022983 AK095931 AK295873
RefSeq transcript (Entrez)NM_001114133 NM_024875
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SYNPO2L
Cluster EST : UnigeneHs.645273 [ NCBI ]
CGAP (NCI)Hs.645273
Alternative Splicing GalleryENSG00000166317
Gene ExpressionSYNPO2L [ NCBI-GEO ]   SYNPO2L [ EBI - ARRAY_EXPRESS ]   SYNPO2L [ SEEK ]   SYNPO2L [ MEM ]
Gene Expression Viewer (FireBrowse)SYNPO2L [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79933
GTEX Portal (Tissue expression)SYNPO2L
Human Protein AtlasENSG00000166317-SYNPO2L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H987   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H987  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H987
Splice isoforms : SwissVarQ9H987
PhosPhoSitePlusQ9H987
Domaine pattern : Prosite (Expaxy)PDZ (PS50106)   
Domains : Interpro (EBI)PDZ    PDZ_sf   
Domain families : Pfam (Sanger)PDZ (PF00595)   
Domain families : Pfam (NCBI)pfam00595   
Domain families : Smart (EMBL)PDZ (SM00228)  
Conserved Domain (NCBI)SYNPO2L
DMDM Disease mutations79933
Blocks (Seattle)SYNPO2L
SuperfamilyQ9H987
Human Protein Atlas [tissue]ENSG00000166317-SYNPO2L [tissue]
Peptide AtlasQ9H987
HPRD15457
IPIIPI00456601   IPI00016425   IPI00854720   
Protein Interaction databases
DIP (DOE-UCLA)Q9H987
IntAct (EBI)Q9H987
FunCoupENSG00000166317
BioGRIDSYNPO2L
STRING (EMBL)SYNPO2L
ZODIACSYNPO2L
Ontologies - Pathways
QuickGOQ9H987
Ontology : AmiGOheart morphogenesis  actin binding  nucleus  nucleus  nucleoplasm  cytosol  actin cytoskeleton  nuclear speck  Z disc  Z disc  cell junction  positive regulation of actin filament bundle assembly  positive regulation of Rho protein signal transduction  sarcomere organization  positive regulation of stress fiber assembly  
Ontology : EGO-EBIheart morphogenesis  actin binding  nucleus  nucleus  nucleoplasm  cytosol  actin cytoskeleton  nuclear speck  Z disc  Z disc  cell junction  positive regulation of actin filament bundle assembly  positive regulation of Rho protein signal transduction  sarcomere organization  positive regulation of stress fiber assembly  
NDEx NetworkSYNPO2L
Atlas of Cancer Signalling NetworkSYNPO2L
Wikipedia pathwaysSYNPO2L
Orthology - Evolution
OrthoDB79933
GeneTree (enSembl)ENSG00000166317
Phylogenetic Trees/Animal Genes : TreeFamSYNPO2L
HOGENOMQ9H987
Homologs : HomoloGeneSYNPO2L
Homology/Alignments : Family Browser (UCSC)SYNPO2L
Gene fusions - Rearrangements
Fusion : QuiverSYNPO2L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYNPO2L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYNPO2L
dbVarSYNPO2L
ClinVarSYNPO2L
1000_GenomesSYNPO2L 
Exome Variant ServerSYNPO2L
ExAC (Exome Aggregation Consortium)ENSG00000166317
GNOMAD BrowserENSG00000166317
Varsome BrowserSYNPO2L
Genetic variants : HAPMAP79933
Genomic Variants (DGV)SYNPO2L [DGVbeta]
DECIPHERSYNPO2L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYNPO2L 
Mutations
ICGC Data PortalSYNPO2L 
TCGA Data PortalSYNPO2L 
Broad Tumor PortalSYNPO2L
OASIS PortalSYNPO2L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYNPO2L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSYNPO2L
Mutations and Diseases : HGMDSYNPO2L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SYNPO2L
DgiDB (Drug Gene Interaction Database)SYNPO2L
DoCM (Curated mutations)SYNPO2L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYNPO2L (select a term)
intoGenSYNPO2L
Cancer3DSYNPO2L(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSYNPO2L
MedgenSYNPO2L
Genetic Testing Registry SYNPO2L
NextProtQ9H987 [Medical]
TSGene79933
GENETestsSYNPO2L
Target ValidationSYNPO2L
Huge Navigator SYNPO2L [HugePedia]
snp3D : Map Gene to Disease79933
BioCentury BCIQSYNPO2L
ClinGenSYNPO2L
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79933
Chemical/Pharm GKB GenePA134889033
Clinical trialSYNPO2L
Miscellaneous
canSAR (ICR)SYNPO2L (select the gene name)
DataMed IndexSYNPO2L
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYNPO2L
EVEXSYNPO2L
GoPubMedSYNPO2L
iHOPSYNPO2L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Sep 3 16:09:11 CEST 2019
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