Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SYNRG (synergin gamma)

Identity

Alias_namesAP1GBP1
AP1 gamma subunit binding protein 1
Alias_symbol (synonym)SYNG
MGC104959
Other alias
HGNC (Hugo) SYNRG
LocusID (NCBI) 11276
Atlas_Id 661
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 37514797 and ends at 37609438 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CRIM1 (2p22.3) / SYNRG (17q12)SYNRG (17q12) / ADAR (1q21.3)SYNRG (17q12) / CCR7 (17q21.2)
SYNRG (17q12) / EVX1 (7p15.2)SYNRG (17q12) / KRT33A (17q21.2)SYNRG (17q12) / SYNRG (17q12)
SYNRG (17q12) / ZNF876P (4p16.3)TOB1 (17q21.33) / SYNRG (17q12)SYNRG 17q12 / CCR7 17q21.2
SYNRG 17q12 / KRT33A 17q21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SYNRG   557
Cards
Entrez_Gene (NCBI)SYNRG  11276  synergin gamma
AliasesAP1GBP1; SYNG
GeneCards (Weizmann)SYNRG
Ensembl hg19 (Hinxton)ENSG00000275066 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000275066 [Gene_View]  chr17:37514797-37609438 [Contig_View]  SYNRG [Vega]
ICGC DataPortalENSG00000275066
TCGA cBioPortalSYNRG
AceView (NCBI)SYNRG
Genatlas (Paris)SYNRG
WikiGenes11276
SOURCE (Princeton)SYNRG
Genetics Home Reference (NIH)SYNRG
Genomic and cartography
GoldenPath hg38 (UCSC)SYNRG  -     chr17:37514797-37609438 -  17q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYNRG  -     17q12   [Description]    (hg19-Feb_2009)
EnsemblSYNRG - 17q12 [CytoView hg19]  SYNRG - 17q12 [CytoView hg38]
Mapping of homologs : NCBISYNRG [Mapview hg19]  SYNRG [Mapview hg38]
OMIM607291   
Gene and transcription
Genbank (Entrez)AF169548 AK025335 AK025700 AK091801 AK126988
RefSeq transcript (Entrez)NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_187614
Consensus coding sequences : CCDS (NCBI)SYNRG
Cluster EST : UnigeneHs.594647 [ NCBI ]
CGAP (NCI)Hs.594647
Alternative Splicing GalleryENSG00000275066
Gene ExpressionSYNRG [ NCBI-GEO ]   SYNRG [ EBI - ARRAY_EXPRESS ]   SYNRG [ SEEK ]   SYNRG [ MEM ]
Gene Expression Viewer (FireBrowse)SYNRG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11276
GTEX Portal (Tissue expression)SYNRG
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UMZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UMZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UMZ2
Splice isoforms : SwissVarQ9UMZ2
PhosPhoSitePlusQ9UMZ2
Domaine pattern : Prosite (Expaxy)EH (PS50031)   
Domains : Interpro (EBI)EF-hand-dom_pair    EH_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)EH (SM00027)  
Conserved Domain (NCBI)SYNRG
DMDM Disease mutations11276
Blocks (Seattle)SYNRG
PDB (SRS)2MX7   
PDB (PDBSum)2MX7   
PDB (IMB)2MX7   
PDB (RSDB)2MX7   
Structural Biology KnowledgeBase2MX7   
SCOP (Structural Classification of Proteins)2MX7   
CATH (Classification of proteins structures)2MX7   
SuperfamilyQ9UMZ2
Human Protein AtlasENSG00000275066
Peptide AtlasQ9UMZ2
HPRD06291
IPIIPI00297931   IPI00827622   IPI00798416   IPI00964301   IPI00444646   IPI00943985   IPI00943538   IPI00943571   IPI00943682   
Protein Interaction databases
DIP (DOE-UCLA)Q9UMZ2
IntAct (EBI)Q9UMZ2
FunCoupENSG00000275066
BioGRIDSYNRG
STRING (EMBL)SYNRG
ZODIACSYNRG
Ontologies - Pathways
QuickGOQ9UMZ2
Ontology : AmiGOprotein binding  cytoplasm  Golgi apparatus  intracellular protein transport  endocytosis  AP-1 adaptor complex  
Ontology : EGO-EBIprotein binding  cytoplasm  Golgi apparatus  intracellular protein transport  endocytosis  AP-1 adaptor complex  
NDEx NetworkSYNRG
Atlas of Cancer Signalling NetworkSYNRG
Wikipedia pathwaysSYNRG
Orthology - Evolution
OrthoDB11276
GeneTree (enSembl)ENSG00000275066
Phylogenetic Trees/Animal Genes : TreeFamSYNRG
HOVERGENQ9UMZ2
HOGENOMQ9UMZ2
Homologs : HomoloGeneSYNRG
Homology/Alignments : Family Browser (UCSC)SYNRG
Gene fusions - Rearrangements
Fusion : MitelmanSYNRG/CCR7 [17q12/17q21.2]  
Fusion : MitelmanSYNRG/KRT33A [17q12/17q21.2]  [t(17;17)(q12;q21)]  
Fusion : MitelmanTOB1/SYNRG [17q21.33/17q12]  [t(17;17)(q12;q21)]  
Fusion: TCGASYNRG 17q12 CCR7 17q21.2 BRCA
Fusion: TCGASYNRG 17q12 KRT33A 17q21.2 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYNRG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYNRG
dbVarSYNRG
ClinVarSYNRG
1000_GenomesSYNRG 
Exome Variant ServerSYNRG
ExAC (Exome Aggregation Consortium)SYNRG (select the gene name)
Genetic variants : HAPMAP11276
Genomic Variants (DGV)SYNRG [DGVbeta]
DECIPHERSYNRG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYNRG 
Mutations
ICGC Data PortalSYNRG 
TCGA Data PortalSYNRG 
Broad Tumor PortalSYNRG
OASIS PortalSYNRG [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSYNRG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SYNRG
DgiDB (Drug Gene Interaction Database)SYNRG
DoCM (Curated mutations)SYNRG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYNRG (select a term)
intoGenSYNRG
Cancer3DSYNRG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607291   
Orphanet
MedgenSYNRG
Genetic Testing Registry SYNRG
NextProtQ9UMZ2 [Medical]
TSGene11276
GENETestsSYNRG
Target ValidationSYNRG
Huge Navigator SYNRG [HugePedia]
snp3D : Map Gene to Disease11276
BioCentury BCIQSYNRG
ClinGenSYNRG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11276
Chemical/Pharm GKB GenePA24847
Clinical trialSYNRG
Miscellaneous
canSAR (ICR)SYNRG (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYNRG
EVEXSYNRG
GoPubMedSYNRG
iHOPSYNRG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:58:19 CEST 2017

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