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SYP (synaptophysin)

Identity

Alias_symbol (synonym)MRX96
Other aliasMRXSYP
HGNC (Hugo) SYP
LocusID (NCBI) 6855
Atlas_Id 43634
Location Xp11.23  [Link to chromosome band Xp11]
Location_base_pair Starts at 49187812 and ends at 49200202 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SYP (Xp11.23) / CPB1 (3q24)SYP (Xp11.23) / CYFIP2 (5q33.3)SYP (Xp11.23) / TSPAN7 (Xp11.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SYP   11506
Cards
Entrez_Gene (NCBI)SYP  6855  synaptophysin
AliasesMRX96; MRXSYP
GeneCards (Weizmann)SYP
Ensembl hg19 (Hinxton)ENSG00000102003 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000102003 [Gene_View]  ENSG00000102003 [Sequence]  chrX:49187812-49200202 [Contig_View]  SYP [Vega]
ICGC DataPortalENSG00000102003
TCGA cBioPortalSYP
AceView (NCBI)SYP
Genatlas (Paris)SYP
WikiGenes6855
SOURCE (Princeton)SYP
Genetics Home Reference (NIH)SYP
Genomic and cartography
GoldenPath hg38 (UCSC)SYP  -     chrX:49187812-49200202 -  Xp11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYP  -     Xp11.23   [Description]    (hg19-Feb_2009)
EnsemblSYP - Xp11.23 [CytoView hg19]  SYP - Xp11.23 [CytoView hg38]
Mapping of homologs : NCBISYP [Mapview hg19]  SYP [Mapview hg38]
OMIM300802   313475   
Gene and transcription
Genbank (Entrez)AK094376 AK295524 AK313030 AK315953 BC032385
RefSeq transcript (Entrez)NM_003179
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SYP
Cluster EST : UnigeneHs.632804 [ NCBI ]
CGAP (NCI)Hs.632804
Alternative Splicing GalleryENSG00000102003
Gene ExpressionSYP [ NCBI-GEO ]   SYP [ EBI - ARRAY_EXPRESS ]   SYP [ SEEK ]   SYP [ MEM ]
Gene Expression Viewer (FireBrowse)SYP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6855
GTEX Portal (Tissue expression)SYP
Human Protein AtlasENSG00000102003-SYP [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08247   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08247  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08247
Splice isoforms : SwissVarP08247
PhosPhoSitePlusP08247
Domaine pattern : Prosite (Expaxy)MARVEL (PS51225)    SYNAPTOP (PS00604)   
Domains : Interpro (EBI)Marvel    Synaptophysin/porin    SYP   
Domain families : Pfam (Sanger)MARVEL (PF01284)   
Domain families : Pfam (NCBI)pfam01284   
Conserved Domain (NCBI)SYP
DMDM Disease mutations6855
Blocks (Seattle)SYP
SuperfamilyP08247
Human Protein Atlas [tissue]ENSG00000102003-SYP [tissue]
Peptide AtlasP08247
HPRD02435
IPIIPI00027770   IPI01015524   IPI00884383   IPI00946107   IPI00945754   IPI00945386   
Protein Interaction databases
DIP (DOE-UCLA)P08247
IntAct (EBI)P08247
FunCoupENSG00000102003
BioGRIDSYP
STRING (EMBL)SYP
ZODIACSYP
Ontologies - Pathways
QuickGOP08247
Ontology : AmiGOendocytosis  synaptic vesicle  cholesterol binding  synaptic vesicle maturation  cell junction  integral component of synaptic vesicle membrane  neuromuscular junction  SH2 domain binding  presynaptic membrane  identical protein binding  neuron projection  terminal bouton  protein self-association  regulation of long-term neuronal synaptic plasticity  regulation of short-term neuronal synaptic plasticity  synaptic vesicle endocytosis  synaptic vesicle membrane organization  presynaptic active zone  excitatory synapse  cellular response to organic substance  Schaffer collateral - CA1 synapse  regulation of synaptic vesicle exocytosis  regulation of opioid receptor signaling pathway  
Ontology : EGO-EBIendocytosis  synaptic vesicle  cholesterol binding  synaptic vesicle maturation  cell junction  integral component of synaptic vesicle membrane  neuromuscular junction  SH2 domain binding  presynaptic membrane  identical protein binding  neuron projection  terminal bouton  protein self-association  regulation of long-term neuronal synaptic plasticity  regulation of short-term neuronal synaptic plasticity  synaptic vesicle endocytosis  synaptic vesicle membrane organization  presynaptic active zone  excitatory synapse  cellular response to organic substance  Schaffer collateral - CA1 synapse  regulation of synaptic vesicle exocytosis  regulation of opioid receptor signaling pathway  
NDEx NetworkSYP
Atlas of Cancer Signalling NetworkSYP
Wikipedia pathwaysSYP
Orthology - Evolution
OrthoDB6855
GeneTree (enSembl)ENSG00000102003
Phylogenetic Trees/Animal Genes : TreeFamSYP
HOVERGENP08247
HOGENOMP08247
Homologs : HomoloGeneSYP
Homology/Alignments : Family Browser (UCSC)SYP
Gene fusions - Rearrangements
Fusion : QuiverSYP
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYP
dbVarSYP
ClinVarSYP
1000_GenomesSYP 
Exome Variant ServerSYP
ExAC (Exome Aggregation Consortium)ENSG00000102003
GNOMAD BrowserENSG00000102003
Varsome BrowserSYP
Genetic variants : HAPMAP6855
Genomic Variants (DGV)SYP [DGVbeta]
DECIPHERSYP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYP 
Mutations
ICGC Data PortalSYP 
TCGA Data PortalSYP 
Broad Tumor PortalSYP
OASIS PortalSYP [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSYP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SYP
DgiDB (Drug Gene Interaction Database)SYP
DoCM (Curated mutations)SYP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYP (select a term)
intoGenSYP
Cancer3DSYP(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300802    313475   
Orphanet3256   
DisGeNETSYP
MedgenSYP
Genetic Testing Registry SYP
NextProtP08247 [Medical]
TSGene6855
GENETestsSYP
Target ValidationSYP
Huge Navigator SYP [HugePedia]
snp3D : Map Gene to Disease6855
BioCentury BCIQSYP
ClinGenSYP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6855
Chemical/Pharm GKB GenePA36288
Clinical trialSYP
Miscellaneous
canSAR (ICR)SYP (select the gene name)
Probes
Litterature
PubMed82 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYP
EVEXSYP
GoPubMedSYP
iHOPSYP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:43:17 CET 2018

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