Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SYT11 (synaptotagmin 11)

Identity

Alias (NCBI)SYT12
sytXI
HGNC (Hugo) SYT11
HGNC Alias symbKIAA0080
MGC10881
MGC17226
DKFZp781D015
HGNC Previous namesynaptotagmin XI
LocusID (NCBI) 23208
Atlas_Id 55828
Location 1q22  [Link to chromosome band 1q22]
Location_base_pair Starts at 155859567 and ends at 155885199 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LMNA (1q22) / SYT11 (1q22)PI4KB (1q21.3) / SYT11 (1q22)SEPT11 (4q21.1) / SYT11 (1q22)
SYT11 (1q22) / HMGB1 (13q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SYT11   19239
Cards
Entrez_Gene (NCBI)SYT11    synaptotagmin 11
AliasesSYT12; sytXI
GeneCards (Weizmann)SYT11
Ensembl hg19 (Hinxton)ENSG00000132718 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000132718 [Gene_View]  ENSG00000132718 [Sequence]  chr1:155859567-155885199 [Contig_View]  SYT11 [Vega]
ICGC DataPortalENSG00000132718
TCGA cBioPortalSYT11
AceView (NCBI)SYT11
Genatlas (Paris)SYT11
SOURCE (Princeton)SYT11
Genetics Home Reference (NIH)SYT11
Genomic and cartography
GoldenPath hg38 (UCSC)SYT11  -     chr1:155859567-155885199 +  1q22   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYT11  -     1q22   [Description]    (hg19-Feb_2009)
GoldenPathSYT11 - 1q22 [CytoView hg19]  SYT11 - 1q22 [CytoView hg38]
ImmunoBaseENSG00000132718
Genome Data Viewer NCBISYT11 [Mapview hg19]  
OMIM608741   
Gene and transcription
Genbank (Entrez)AA824539 AK026178 AK027540 AK074931 AK296378
RefSeq transcript (Entrez)NM_152280
Consensus coding sequences : CCDS (NCBI)SYT11
Gene ExpressionSYT11 [ NCBI-GEO ]   SYT11 [ EBI - ARRAY_EXPRESS ]   SYT11 [ SEEK ]   SYT11 [ MEM ]
Gene Expression Viewer (FireBrowse)SYT11 [ Firebrowse - Broad ]
GenevisibleExpression of SYT11 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23208
GTEX Portal (Tissue expression)SYT11
Human Protein AtlasENSG00000132718-SYT11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BT88   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BT88  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BT88
PhosPhoSitePlusQ9BT88
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (EBI)C2_dom    C2_domain_sf    Synaptotagmin    SYT11   
Domain families : Pfam (Sanger)C2 (PF00168)   
Domain families : Pfam (NCBI)pfam00168   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)SYT11
SuperfamilyQ9BT88
AlphaFold pdb e-kbQ9BT88   
Human Protein Atlas [tissue]ENSG00000132718-SYT11 [tissue]
HPRD12289
Protein Interaction databases
DIP (DOE-UCLA)Q9BT88
IntAct (EBI)Q9BT88
BioGRIDSYT11
STRING (EMBL)SYT11
ZODIACSYT11
Ontologies - Pathways
QuickGOQ9BT88
Ontology : AmiGOSNARE binding  plasma membrane repair  phosphatidylserine binding  negative regulation of cytokine production  phagocytic cup  calcium ion binding  calcium ion binding  protein binding  calcium-dependent phospholipid binding  calcium-dependent phospholipid binding  lysosome  lysosomal membrane  trans-Golgi network  plasma membrane  vesicle fusion  autophagy  learning  memory  synaptic vesicle  synaptic vesicle  synaptic vesicle  regulation of dopamine secretion  postsynaptic density  vesicle-mediated transport  calcium-ion regulated exocytosis  regulation of calcium ion-dependent exocytosis  clathrin binding  axon  axon  dendrite  clathrin-coated vesicle membrane  translation initiation factor binding  ubiquitin protein ligase binding  vesicle  early phagosome  negative regulation of interleukin-6 production  negative regulation of tumor necrosis factor production  negative regulation of dopamine secretion  identical protein binding  neuron projection  terminal bouton  dendritic spine  perikaryon  synapse  phagocytic vesicle  negative regulation of endocytosis  negative regulation of neurotransmitter secretion  perinuclear region of cytoplasm  beta-tubulin binding  presynaptic active zone membrane  negative regulation of phagocytosis  establishment of vesicle localization  recycling endosome  recycling endosome membrane  excitatory synapse  inhibitory synapse  exocytic vesicle  cellular response to calcium ion  Schaffer collateral - CA1 synapse  presynapse  integral component of presynaptic active zone membrane  negative regulation of clathrin-dependent endocytosis  negative regulation of synaptic vesicle endocytosis  regulation of defense response to bacterium  negative regulation of microglial cell activation  negative regulation of membrane invagination  regulation of phagosome maturation  positive regulation of protein localization to phagocytic vesicle  negative regulation of clathrin-coated pit assembly  calcium ion regulated lysosome exocytosis  
Ontology : EGO-EBISNARE binding  plasma membrane repair  phosphatidylserine binding  negative regulation of cytokine production  phagocytic cup  calcium ion binding  calcium ion binding  protein binding  calcium-dependent phospholipid binding  calcium-dependent phospholipid binding  lysosome  lysosomal membrane  trans-Golgi network  plasma membrane  vesicle fusion  autophagy  learning  memory  synaptic vesicle  synaptic vesicle  synaptic vesicle  regulation of dopamine secretion  postsynaptic density  vesicle-mediated transport  calcium-ion regulated exocytosis  regulation of calcium ion-dependent exocytosis  clathrin binding  axon  axon  dendrite  clathrin-coated vesicle membrane  translation initiation factor binding  ubiquitin protein ligase binding  vesicle  early phagosome  negative regulation of interleukin-6 production  negative regulation of tumor necrosis factor production  negative regulation of dopamine secretion  identical protein binding  neuron projection  terminal bouton  dendritic spine  perikaryon  synapse  phagocytic vesicle  negative regulation of endocytosis  negative regulation of neurotransmitter secretion  perinuclear region of cytoplasm  beta-tubulin binding  presynaptic active zone membrane  negative regulation of phagocytosis  establishment of vesicle localization  recycling endosome  recycling endosome membrane  excitatory synapse  inhibitory synapse  exocytic vesicle  cellular response to calcium ion  Schaffer collateral - CA1 synapse  presynapse  integral component of presynaptic active zone membrane  negative regulation of clathrin-dependent endocytosis  negative regulation of synaptic vesicle endocytosis  regulation of defense response to bacterium  negative regulation of microglial cell activation  negative regulation of membrane invagination  regulation of phagosome maturation  positive regulation of protein localization to phagocytic vesicle  negative regulation of clathrin-coated pit assembly  calcium ion regulated lysosome exocytosis  
NDEx NetworkSYT11
Atlas of Cancer Signalling NetworkSYT11
Wikipedia pathwaysSYT11
Orthology - Evolution
OrthoDB23208
GeneTree (enSembl)ENSG00000132718
Phylogenetic Trees/Animal Genes : TreeFamSYT11
Homologs : HomoloGeneSYT11
Homology/Alignments : Family Browser (UCSC)SYT11
Gene fusions - Rearrangements
Fusion : QuiverSYT11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYT11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYT11
dbVarSYT11
ClinVarSYT11
MonarchSYT11
1000_GenomesSYT11 
Exome Variant ServerSYT11
GNOMAD BrowserENSG00000132718
Varsome BrowserSYT11
ACMGSYT11 variants
VarityQ9BT88
Genomic Variants (DGV)SYT11 [DGVbeta]
DECIPHERSYT11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYT11 
Mutations
ICGC Data PortalSYT11 
TCGA Data PortalSYT11 
Broad Tumor PortalSYT11
OASIS PortalSYT11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYT11  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSYT11
Mutations and Diseases : HGMDSYT11
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSYT11
DgiDB (Drug Gene Interaction Database)SYT11
DoCM (Curated mutations)SYT11
CIViC (Clinical Interpretations of Variants in Cancer)SYT11
Cancer3DSYT11
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608741   
Orphanet
DisGeNETSYT11
MedgenSYT11
Genetic Testing Registry SYT11
NextProtQ9BT88 [Medical]
GENETestsSYT11
Target ValidationSYT11
Huge Navigator SYT11 [HugePedia]
ClinGenSYT11
Clinical trials, drugs, therapy
MyCancerGenomeSYT11
Protein Interactions : CTDSYT11
Pharm GKB GenePA134898675
PharosQ9BT88
Clinical trialSYT11
Miscellaneous
canSAR (ICR)SYT11
HarmonizomeSYT11
DataMed IndexSYT11
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSYT11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:02 CEST 2021

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