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SYT12 (synaptotagmin 12)

Identity

Alias_namessynaptotagmin XII
Alias_symbol (synonym)SRG1
Other aliasSYT11
sytXII
HGNC (Hugo) SYT12
LocusID (NCBI) 91683
Atlas_Id 56276
Location 11q13.2  [Link to chromosome band 11q13]
Location_base_pair Starts at 66790190 and ends at 66818334 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
INTS5 (11q12.3) / SYT12 (11q13.2)KDM2A (11q13.2) / SYT12 (11q13.2)SYT12 (11q13.2) / SH3GLB1 (1p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SYT12   18381
Cards
Entrez_Gene (NCBI)SYT12  91683  synaptotagmin 12
AliasesSYT11; sytXII
GeneCards (Weizmann)SYT12
Ensembl hg19 (Hinxton)ENSG00000173227 [Gene_View]  chr11:66790190-66818334 [Contig_View]  SYT12 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173227 [Gene_View]  chr11:66790190-66818334 [Contig_View]  SYT12 [Vega]
ICGC DataPortalENSG00000173227
TCGA cBioPortalSYT12
AceView (NCBI)SYT12
Genatlas (Paris)SYT12
WikiGenes91683
SOURCE (Princeton)SYT12
Genetics Home Reference (NIH)SYT12
Genomic and cartography
GoldenPath hg19 (UCSC)SYT12  -     chr11:66790190-66818334 +  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SYT12  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblSYT12 - 11q13.2 [CytoView hg19]  SYT12 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBISYT12 [Mapview hg19]  SYT12 [Mapview hg38]
OMIM606436   
Gene and transcription
Genbank (Entrez)-
RefSeq transcript (Entrez)NM_001177880 NM_001318773 NM_001318775 NM_177963
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SYT12
Cluster EST : UnigeneHs.287636 [ NCBI ]
CGAP (NCI)Hs.287636
Alternative Splicing GalleryENSG00000173227
Gene ExpressionSYT12 [ NCBI-GEO ]   SYT12 [ EBI - ARRAY_EXPRESS ]   SYT12 [ SEEK ]   SYT12 [ MEM ]
Gene Expression Viewer (FireBrowse)SYT12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)91683
GTEX Portal (Tissue expression)SYT12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IV01   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IV01  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IV01
Splice isoforms : SwissVarQ8IV01
PhosPhoSitePlusQ8IV01
Domaine pattern : Prosite (Expaxy)C2 (PS50004)   
Domains : Interpro (EBI)C2_dom    SYT12   
Domain families : Pfam (Sanger)C2 (PF00168)   
Domain families : Pfam (NCBI)pfam00168   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)SYT12
DMDM Disease mutations91683
Blocks (Seattle)SYT12
SuperfamilyQ8IV01
Human Protein AtlasENSG00000173227
Peptide AtlasQ8IV01
HPRD07337
IPIIPI00219472   IPI00976762   
Protein Interaction databases
DIP (DOE-UCLA)Q8IV01
IntAct (EBI)Q8IV01
FunCoupENSG00000173227
BioGRIDSYT12
STRING (EMBL)SYT12
ZODIACSYT12
Ontologies - Pathways
QuickGOQ8IV01
Ontology : AmiGOcalcium ion binding  calcium-dependent phospholipid binding  plasma membrane  vesicle fusion  integral component of membrane  regulation of calcium ion-dependent exocytosis  syntaxin binding  cell junction  clathrin binding  synaptic vesicle membrane  regulation of neurotransmitter secretion  synaptic vesicle endocytosis  calcium ion-regulated exocytosis of neurotransmitter  spontaneous exocytosis of neurotransmitter  long-term synaptic potentiation  
Ontology : EGO-EBIcalcium ion binding  calcium-dependent phospholipid binding  plasma membrane  vesicle fusion  integral component of membrane  regulation of calcium ion-dependent exocytosis  syntaxin binding  cell junction  clathrin binding  synaptic vesicle membrane  regulation of neurotransmitter secretion  synaptic vesicle endocytosis  calcium ion-regulated exocytosis of neurotransmitter  spontaneous exocytosis of neurotransmitter  long-term synaptic potentiation  
NDEx NetworkSYT12
Atlas of Cancer Signalling NetworkSYT12
Wikipedia pathwaysSYT12
Orthology - Evolution
OrthoDB91683
GeneTree (enSembl)ENSG00000173227
Phylogenetic Trees/Animal Genes : TreeFamSYT12
HOVERGENQ8IV01
HOGENOMQ8IV01
Homologs : HomoloGeneSYT12
Homology/Alignments : Family Browser (UCSC)SYT12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYT12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYT12
dbVarSYT12
ClinVarSYT12
1000_GenomesSYT12 
Exome Variant ServerSYT12
ExAC (Exome Aggregation Consortium)SYT12 (select the gene name)
Genetic variants : HAPMAP91683
Genomic Variants (DGV)SYT12 [DGVbeta]
DECIPHER (Syndromes)11:66790190-66818334  ENSG00000173227
CONAN: Copy Number AnalysisSYT12 
Mutations
ICGC Data PortalSYT12 
TCGA Data PortalSYT12 
Broad Tumor PortalSYT12
OASIS PortalSYT12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYT12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSYT12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SYT12
DgiDB (Drug Gene Interaction Database)SYT12
DoCM (Curated mutations)SYT12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYT12 (select a term)
intoGenSYT12
Cancer3DSYT12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606436   
Orphanet
MedgenSYT12
Genetic Testing Registry SYT12
NextProtQ8IV01 [Medical]
TSGene91683
GENETestsSYT12
Huge Navigator SYT12 [HugePedia]
snp3D : Map Gene to Disease91683
BioCentury BCIQSYT12
ClinGenSYT12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD91683
Chemical/Pharm GKB GenePA38321
Clinical trialSYT12
Miscellaneous
canSAR (ICR)SYT12 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYT12
EVEXSYT12
GoPubMedSYT12
iHOPSYT12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:21:38 CEST 2017

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