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SYTL1 (synaptotagmin like 1)

Identity

Alias (NCBI)JFC1
SLP1
HGNC (Hugo) SYTL1
HGNC Alias symbSLP1
JFC1
FLJ14996
exophilin-7
HGNC Previous namesynaptotagmin-like 1
LocusID (NCBI) 84958
Atlas_Id 46454
Location 1p36.11  [Link to chromosome band 1p36]
Location_base_pair Starts at 27342022 and ends at 27353932 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C2CD3 (11q13.4) / SYTL1 (1p36.11)PLD2 (17p13.2) / SYTL1 (1p36.11)PSMC1 (14q32.11) / SYTL1 (1p36.11)
SYTL1 (1p36.11) / SYTL1 (1p36.11)SYTL1 (1p36.11) / WDTC1 (1p36.11)YTHDF2 (1p35.3) / SYTL1 (1p36.11)
C2CD3 11q13.4 / SYTL1 1p36.11

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SYTL1   15584
Cards
Entrez_Gene (NCBI)SYTL1    synaptotagmin like 1
AliasesJFC1; SLP1
GeneCards (Weizmann)SYTL1
Ensembl hg19 (Hinxton)ENSG00000142765 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142765 [Gene_View]  ENSG00000142765 [Sequence]  chr1:27342022-27353932 [Contig_View]  SYTL1 [Vega]
ICGC DataPortalENSG00000142765
TCGA cBioPortalSYTL1
AceView (NCBI)SYTL1
Genatlas (Paris)SYTL1
SOURCE (Princeton)SYTL1
Genetics Home Reference (NIH)SYTL1
Genomic and cartography
GoldenPath hg38 (UCSC)SYTL1  -     chr1:27342022-27353932 +  1p36.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYTL1  -     1p36.11   [Description]    (hg19-Feb_2009)
GoldenPathSYTL1 - 1p36.11 [CytoView hg19]  SYTL1 - 1p36.11 [CytoView hg38]
ImmunoBaseENSG00000142765
Genome Data Viewer NCBISYTL1 [Mapview hg19]  
OMIM608042   
Gene and transcription
Genbank (Entrez)AK027902 AK074154 AK096437 AK097172 AK126120
RefSeq transcript (Entrez)NM_001193308 NM_032872
Consensus coding sequences : CCDS (NCBI)SYTL1
Gene ExpressionSYTL1 [ NCBI-GEO ]   SYTL1 [ EBI - ARRAY_EXPRESS ]   SYTL1 [ SEEK ]   SYTL1 [ MEM ]
Gene Expression Viewer (FireBrowse)SYTL1 [ Firebrowse - Broad ]
GenevisibleExpression of SYTL1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84958
GTEX Portal (Tissue expression)SYTL1
Human Protein AtlasENSG00000142765-SYTL1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IYJ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IYJ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IYJ3
PhosPhoSitePlusQ8IYJ3
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    RABBD (PS50916)   
Domains : Interpro (EBI)C2_dom    C2_domain_sf    Rab_BD    Sytl1    SYTL1-5_C2B    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)C2 (PF00168)   
Domain families : Pfam (NCBI)pfam00168   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)SYTL1
SuperfamilyQ8IYJ3
AlphaFold pdb e-kbQ8IYJ3   
Human Protein Atlas [tissue]ENSG00000142765-SYTL1 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8IYJ3
IntAct (EBI)Q8IYJ3
BioGRIDSYTL1
STRING (EMBL)SYTL1
ZODIACSYTL1
Ontologies - Pathways
QuickGOQ8IYJ3
Ontology : AmiGOprotein binding  plasma membrane  plasma membrane  intracellular protein transport  exocytosis  exocytosis  extrinsic component of plasma membrane  small GTPase binding  microvillus membrane  neurexin family protein binding  neurexin family protein binding  melanosome  extracellular exosome  exocytic vesicle  
Ontology : EGO-EBIprotein binding  plasma membrane  plasma membrane  intracellular protein transport  exocytosis  exocytosis  extrinsic component of plasma membrane  small GTPase binding  microvillus membrane  neurexin family protein binding  neurexin family protein binding  melanosome  extracellular exosome  exocytic vesicle  
NDEx NetworkSYTL1
Atlas of Cancer Signalling NetworkSYTL1
Wikipedia pathwaysSYTL1
Orthology - Evolution
OrthoDB84958
GeneTree (enSembl)ENSG00000142765
Phylogenetic Trees/Animal Genes : TreeFamSYTL1
Homologs : HomoloGeneSYTL1
Homology/Alignments : Family Browser (UCSC)SYTL1
Gene fusions - Rearrangements
Fusion : MitelmanC2CD3/SYTL1 [11q13.4/1p36.11]  
Fusion : MitelmanYTHDF2/SYTL1 [1p35.3/1p36.11]  
Fusion : QuiverSYTL1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYTL1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYTL1
dbVarSYTL1
ClinVarSYTL1
MonarchSYTL1
1000_GenomesSYTL1 
Exome Variant ServerSYTL1
GNOMAD BrowserENSG00000142765
Varsome BrowserSYTL1
ACMGSYTL1 variants
VarityQ8IYJ3
Genomic Variants (DGV)SYTL1 [DGVbeta]
DECIPHERSYTL1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYTL1 
Mutations
ICGC Data PortalSYTL1 
TCGA Data PortalSYTL1 
Broad Tumor PortalSYTL1
OASIS PortalSYTL1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYTL1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSYTL1
Mutations and Diseases : HGMDSYTL1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSYTL1
DgiDB (Drug Gene Interaction Database)SYTL1
DoCM (Curated mutations)SYTL1
CIViC (Clinical Interpretations of Variants in Cancer)SYTL1
Cancer3DSYTL1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608042   
Orphanet
DisGeNETSYTL1
MedgenSYTL1
Genetic Testing Registry SYTL1
NextProtQ8IYJ3 [Medical]
GENETestsSYTL1
Target ValidationSYTL1
Huge Navigator SYTL1 [HugePedia]
ClinGenSYTL1
Clinical trials, drugs, therapy
MyCancerGenomeSYTL1
Protein Interactions : CTDSYTL1
Pharm GKB GenePA134921815
PharosQ8IYJ3
Clinical trialSYTL1
Miscellaneous
canSAR (ICR)SYTL1
HarmonizomeSYTL1
DataMed IndexSYTL1
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSYTL1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:34:05 CEST 2021

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