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SYTL5 (synaptotagmin like 5)

Identity

Alias_namessynaptotagmin-like 5
Other aliasslp5
HGNC (Hugo) SYTL5
LocusID (NCBI) 94122
Atlas_Id 55964
Location Xp11.4  [Link to chromosome band Xp11]
Location_base_pair Starts at 38033534 and ends at 38128820 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KMT2C (7q36.1) / SYTL5 (Xp11.4)TCF3 (19p13.3) / SYTL5 (Xp11.4)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SYTL5   15589
Cards
Entrez_Gene (NCBI)SYTL5  94122  synaptotagmin like 5
Aliasesslp5
GeneCards (Weizmann)SYTL5
Ensembl hg19 (Hinxton)ENSG00000147041 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000147041 [Gene_View]  chrX:38033534-38128820 [Contig_View]  SYTL5 [Vega]
ICGC DataPortalENSG00000147041
TCGA cBioPortalSYTL5
AceView (NCBI)SYTL5
Genatlas (Paris)SYTL5
WikiGenes94122
SOURCE (Princeton)SYTL5
Genetics Home Reference (NIH)SYTL5
Genomic and cartography
GoldenPath hg38 (UCSC)SYTL5  -     chrX:38033534-38128820 +  Xp11.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SYTL5  -     Xp11.4   [Description]    (hg19-Feb_2009)
EnsemblSYTL5 - Xp11.4 [CytoView hg19]  SYTL5 - Xp11.4 [CytoView hg38]
Mapping of homologs : NCBISYTL5 [Mapview hg19]  SYTL5 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB080222 AK125106 AL135038 BC131585 BX647688
RefSeq transcript (Entrez)NM_001163334 NM_001163335 NM_138780
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SYTL5
Cluster EST : UnigeneHs.662334 [ NCBI ]
CGAP (NCI)Hs.662334
Alternative Splicing GalleryENSG00000147041
Gene ExpressionSYTL5 [ NCBI-GEO ]   SYTL5 [ EBI - ARRAY_EXPRESS ]   SYTL5 [ SEEK ]   SYTL5 [ MEM ]
Gene Expression Viewer (FireBrowse)SYTL5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)94122
GTEX Portal (Tissue expression)SYTL5
Human Protein AtlasENSG00000147041-SYTL5 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TDW5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TDW5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TDW5
Splice isoforms : SwissVarQ8TDW5
PhosPhoSitePlusQ8TDW5
Domaine pattern : Prosite (Expaxy)C2 (PS50004)    RABBD (PS50916)   
Domains : Interpro (EBI)C2_dom    Rab_BD    Slp5    Znf_FYVE_PHD    Znf_RING/FYVE/PHD   
Domain families : Pfam (Sanger)C2 (PF00168)    FYVE_2 (PF02318)   
Domain families : Pfam (NCBI)pfam00168    pfam02318   
Domain families : Smart (EMBL)C2 (SM00239)  
Conserved Domain (NCBI)SYTL5
DMDM Disease mutations94122
Blocks (Seattle)SYTL5
SuperfamilyQ8TDW5
Human Protein Atlas [tissue]ENSG00000147041-SYTL5 [tissue]
Peptide AtlasQ8TDW5
HPRD06736
IPIIPI00152647   IPI00829637   
Protein Interaction databases
DIP (DOE-UCLA)Q8TDW5
IntAct (EBI)Q8TDW5
FunCoupENSG00000147041
BioGRIDSYTL5
STRING (EMBL)SYTL5
ZODIACSYTL5
Ontologies - Pathways
QuickGOQ8TDW5
Ontology : AmiGOcalcium ion binding  protein binding  calcium-dependent phospholipid binding  plasma membrane  intracellular protein transport  vesicle fusion  Rab GTPase binding  regulation of calcium ion-dependent exocytosis  syntaxin binding  clathrin binding  calcium ion-regulated exocytosis of neurotransmitter  exocytic vesicle  presynapse  
Ontology : EGO-EBIcalcium ion binding  protein binding  calcium-dependent phospholipid binding  plasma membrane  intracellular protein transport  vesicle fusion  Rab GTPase binding  regulation of calcium ion-dependent exocytosis  syntaxin binding  clathrin binding  calcium ion-regulated exocytosis of neurotransmitter  exocytic vesicle  presynapse  
NDEx NetworkSYTL5
Atlas of Cancer Signalling NetworkSYTL5
Wikipedia pathwaysSYTL5
Orthology - Evolution
OrthoDB94122
GeneTree (enSembl)ENSG00000147041
Phylogenetic Trees/Animal Genes : TreeFamSYTL5
HOVERGENQ8TDW5
HOGENOMQ8TDW5
Homologs : HomoloGeneSYTL5
Homology/Alignments : Family Browser (UCSC)SYTL5
Gene fusions - Rearrangements
Tumor Fusion PortalSYTL5
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSYTL5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SYTL5
dbVarSYTL5
ClinVarSYTL5
1000_GenomesSYTL5 
Exome Variant ServerSYTL5
ExAC (Exome Aggregation Consortium)ENSG00000147041
GNOMAD BrowserENSG00000147041
Genetic variants : HAPMAP94122
Genomic Variants (DGV)SYTL5 [DGVbeta]
DECIPHERSYTL5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSYTL5 
Mutations
ICGC Data PortalSYTL5 
TCGA Data PortalSYTL5 
Broad Tumor PortalSYTL5
OASIS PortalSYTL5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSYTL5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSYTL5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch SYTL5
DgiDB (Drug Gene Interaction Database)SYTL5
DoCM (Curated mutations)SYTL5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SYTL5 (select a term)
intoGenSYTL5
Cancer3DSYTL5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETSYTL5
MedgenSYTL5
Genetic Testing Registry SYTL5
NextProtQ8TDW5 [Medical]
TSGene94122
GENETestsSYTL5
Target ValidationSYTL5
Huge Navigator SYTL5 [HugePedia]
snp3D : Map Gene to Disease94122
BioCentury BCIQSYTL5
ClinGenSYTL5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD94122
Chemical/Pharm GKB GenePA37988
Clinical trialSYTL5
Miscellaneous
canSAR (ICR)SYTL5 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSYTL5
EVEXSYTL5
GoPubMedSYTL5
iHOPSYTL5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:37:30 CET 2017

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