Atlas of Genetics and Cytogenetics in Oncology and Haematology

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TAB1 (TGF-beta activated kinase 1/MAP3K7 binding protein 1)

Identity

Other names3'-Tab1
MAP3K7IP1
HGNC (Hugo) TAB1
LocusID (NCBI) 10454
Location 22q13.1
Location_base_pair Starts at 39795759 and ends at 39827887 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)TAB1   18157
Entrez_Gene (NCBI)TAB1  10454  TGF-beta activated kinase 1/MAP3K7 binding protein 1
Cards
GeneCards (Weizmann)TAB1
Ensembl (Hinxton)ENSG00000100324 [Gene_View]  chr22:39795759-39827887 [Contig_View]  TAB1 [Vega]
AceView (NCBI)TAB1
Genatlas (Paris)TAB1
SOURCE (Stanford)NM_006116 NM_153497
Genomic and cartography
GoldenPath (UCSC)TAB1  -  22q13.1   chr22:39795759-39827887 +  22q13.1   [Description]    (hg19-Feb_2009)
EnsemblTAB1 - 22q13.1 [CytoView]
Mapping of homologs : NCBITAB1 [Mapview]
OMIM602615   
Gene and transcription
Genbank (Entrez)AF425640 AI827837 AK291668 AK296314 AK308903
RefSeq transcript (SRS)NM_006116 NM_153497
RefSeq transcript (Entrez)NM_006116 NM_153497
RefSeq genomic (SRS)AC_000154 NC_000022 NC_018933 NG_029549 NT_011520 NW_001838745 NW_004078112
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NG_029549 NT_011520 NW_001838745 NW_004078112
Consensus coding sequences : CCDS (NCBI)TAB1
Cluster EST : UnigeneHs.729080 [ SRS ] Hs.729080 [ NCBI ]
CGAP (NCI)Hs.729080
Alternative Splicing : Fast-db (Paris)GSHG0020030
Alternative Splicing GalleryENSG00000100324
Gene ExpressionTAB1 [ NCBI-GEO ]   TAB1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15750 (SRS) Q15750 (Uniprot)
NextProtQ15750
With graphics : InterProQ15750
Splice isoforms : SwissVarQ15750(Swissvar)
Domains : Interpro (SRS)PP2C-like    Protein_Pase_2C   
Domains : Interpro (EBI)PP2C-like    Protein_Pase_2C   
Related proteins : CluSTrQ15750
Domain families : Pfam (SRS)PP2C (PF00481)   
Domain families : Pfam (Sanger)PP2C (PF00481)   
Domain families : Pfam (NCBI)pfam00481   
Domain families : Smart (EMBL)PP2Cc (SM00332)  
DMDM10454
Blocks (Seattle)Q15750
PDB (SRS)2J4O    2POM    2POP    2YIY   
PDB (PDBSum)2J4O    2POM    2POP    2YIY   
PDB (IMB)2J4O    2POM    2POP    2YIY   
PDB (RSDB)2J4O    2POM    2POP    2YIY   
Human Protein AtlasENSG00000100324
HPRD04012
IPIIPI00019459   IPI00395625   IPI00915903   IPI00916611   
Protein Interaction databases
DIP (DOE-UCLA)Q15750
IntAct (EBI)Q15750
FunCoupENSG00000100324
REACTOMETAB1
Protein Interaction Database10454
BioGRIDTAB1
InParanoidQ15750
Interologous Interaction database Q15750
IntegromeDBTAB1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)TAB1
SNP (GeneSNP Utah)TAB1
SNP : HGBaseTAB1
Genetic variants : HAPMAPTAB1
Somatic Mutations in Cancer : COSMICTAB1 
CONAN: Copy Number AnalysisTAB1 
Mutations and Diseases : HGMDTAB1
OMIM602615   
GENETests602615   
Disease Genetic AssociationTAB1
Huge Navigator TAB1 [HugePedia]  TAB1 [HugeCancerGEM]
Genomic VariantsTAB1  TAB1 [DGVbeta]
snp3D : Map Gene to Disease10454
General knowledge
Homologs : HomoloGeneTAB1
Homology/Alignments : Family Browser (UCSC)TAB1
Phylogenetic Trees/Animal Genes : TreeFamTAB1
Chemical/Protein Interactions : CTD10454
Chemical/Pharm GKB GenePA30604
Clinical trialTAB1
Cancer Resource (Charite)ENSG00000100324
Ontology : AmiGOactivation of MAPKKK activity  activation of MAPK activity  in utero embryonic development  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  heart morphogenesis  catalytic activity  protein binding  cytosol  transforming growth factor beta receptor signaling pathway  I-kappaB kinase/NF-kappaB cascade  JNK cascade  enzyme activator activity  Toll signaling pathway  endosome membrane  kinase activator activity  lung development  toll-like receptor 1 signaling pathway  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  protein complex  innate immune response  positive regulation of NF-kappaB transcription factor activity  stress-activated MAPK cascade  nucleotide-binding oligomerization domain containing signaling pathway  
Ontology : EGO-EBIactivation of MAPKKK activity  activation of MAPK activity  in utero embryonic development  toll-like receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  MyD88-independent toll-like receptor signaling pathway  heart morphogenesis  catalytic activity  protein binding  cytosol  transforming growth factor beta receptor signaling pathway  I-kappaB kinase/NF-kappaB cascade  JNK cascade  enzyme activator activity  Toll signaling pathway  endosome membrane  kinase activator activity  lung development  toll-like receptor 1 signaling pathway  toll-like receptor 2 signaling pathway  toll-like receptor 3 signaling pathway  toll-like receptor 4 signaling pathway  TRIF-dependent toll-like receptor signaling pathway  nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway  protein complex  innate immune response  positive regulation of NF-kappaB transcription factor activity  stress-activated MAPK cascade  nucleotide-binding oligomerization domain containing signaling pathway  
Pathways : BIOCARTATGF beta signaling pathway [Genes]    Toll-Like Receptor Pathway [Genes]    Signal transduction through IL1R [Genes]    NF-kB Signaling Pathway [Genes]    WNT Signaling Pathway [Genes]   
Pathways : KEGGToll-like receptor signaling pathwayMAPK signaling pathway
Other databases
Probes
Litterature
PubMed72 Pubmed reference(s) in Entrez
PubGeneTAB1
iHOPTAB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:59 CEST 2013
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