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TAB3 (TGF-beta activated kinase 1 (MAP3K7) binding protein 3)

Identity

Alias (NCBI)MAP3K7IP3
NAP1
HGNC (Hugo) TAB3
HGNC Alias nameTAK1 binding protein 3
HGNC Previous nameMAP3K7IP3
HGNC Previous namemitogen-activated protein kinase kinase kinase 7 interacting protein 3
 TGF-beta activated kinase 1/MAP3K7 binding protein 3
 TGF-beta activated kinase 1 and MAP3K7 binding protein 3
LocusID (NCBI) 257397
Atlas_Id 51346
Location Xp21.2  [Link to chromosome band Xp21]
Location_base_pair Starts at 30827442 and ends at 30889254 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TAB3 (Xp21.2) / DMD (Xp21.2)TAB3 (Xp21.2) / MAGEB2 (Xp21.2)TAB3 Xp21.2 / DMD Xp21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAB3   30681
Cards
Entrez_Gene (NCBI)TAB3    TGF-beta activated kinase 1 (MAP3K7) binding protein 3
AliasesMAP3K7IP3; NAP1
GeneCards (Weizmann)TAB3
Ensembl hg19 (Hinxton)ENSG00000157625 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157625 [Gene_View]  ENSG00000157625 [Sequence]  chrX:30827442-30889254 [Contig_View]  TAB3 [Vega]
ICGC DataPortalENSG00000157625
TCGA cBioPortalTAB3
AceView (NCBI)TAB3
Genatlas (Paris)TAB3
SOURCE (Princeton)TAB3
Genetics Home Reference (NIH)TAB3
Genomic and cartography
GoldenPath hg38 (UCSC)TAB3  -     chrX:30827442-30889254 -  Xp21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAB3  -     Xp21.2   [Description]    (hg19-Feb_2009)
GoldenPathTAB3 - Xp21.2 [CytoView hg19]  TAB3 - Xp21.2 [CytoView hg38]
ImmunoBaseENSG00000157625
Genome Data Viewer NCBITAB3 [Mapview hg19]  
OMIM300480   
Gene and transcription
Genbank (Entrez)AK096786 AK297274 AL832071 AY331591 AY331592
RefSeq transcript (Entrez)NM_152787 NM_198312
Consensus coding sequences : CCDS (NCBI)TAB3
Gene ExpressionTAB3 [ NCBI-GEO ]   TAB3 [ EBI - ARRAY_EXPRESS ]   TAB3 [ SEEK ]   TAB3 [ MEM ]
Gene Expression Viewer (FireBrowse)TAB3 [ Firebrowse - Broad ]
GenevisibleExpression of TAB3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)257397
GTEX Portal (Tissue expression)TAB3
Human Protein AtlasENSG00000157625-TAB3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5C8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5C8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5C8
PhosPhoSitePlusQ8N5C8
Domaine pattern : Prosite (Expaxy)CUE (PS51140)    ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)CUE    TAB2/3_CUE    Znf_RanBP2    Znf_RanBP2_sf   
Domain families : Pfam (Sanger)CUE (PF02845)   
Domain families : Pfam (NCBI)pfam02845   
Domain families : Smart (EMBL)CUE (SM00546)  ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)TAB3
SuperfamilyQ8N5C8
AlphaFold pdb e-kbQ8N5C8   
Human Protein Atlas [tissue]ENSG00000157625-TAB3 [tissue]
HPRD06738
Protein Interaction databases
DIP (DOE-UCLA)Q8N5C8
IntAct (EBI)Q8N5C8
BioGRIDTAB3
STRING (EMBL)TAB3
ZODIACTAB3
Ontologies - Pathways
QuickGOQ8N5C8
Ontology : AmiGOactivation of MAPK activity  activation of MAPK activity  stimulatory C-type lectin receptor signaling pathway  cytoplasmic pattern recognition receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  protein binding  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  JNK cascade  zinc ion binding  endosome membrane  negative regulation of autophagy  Fc-epsilon receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin binding  positive regulation of NF-kappaB transcription factor activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  interleukin-1-mediated signaling pathway  K63-linked polyubiquitin modification-dependent protein binding  
Ontology : EGO-EBIactivation of MAPK activity  activation of MAPK activity  stimulatory C-type lectin receptor signaling pathway  cytoplasmic pattern recognition receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  protein binding  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  JNK cascade  zinc ion binding  endosome membrane  negative regulation of autophagy  Fc-epsilon receptor signaling pathway  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  positive regulation of I-kappaB kinase/NF-kappaB signaling  ubiquitin binding  positive regulation of NF-kappaB transcription factor activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  interleukin-1-mediated signaling pathway  K63-linked polyubiquitin modification-dependent protein binding  
Pathways : KEGGNF-kappa B signaling pathway    NOD-like receptor signaling pathway    TNF signaling pathway   
NDEx NetworkTAB3
Atlas of Cancer Signalling NetworkTAB3
Wikipedia pathwaysTAB3
Orthology - Evolution
OrthoDB257397
GeneTree (enSembl)ENSG00000157625
Phylogenetic Trees/Animal Genes : TreeFamTAB3
Homologs : HomoloGeneTAB3
Homology/Alignments : Family Browser (UCSC)TAB3
Gene fusions - Rearrangements
Fusion : MitelmanTAB3/DMD [Xp21.2/Xp21.2]  
Fusion : QuiverTAB3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAB3
dbVarTAB3
ClinVarTAB3
MonarchTAB3
1000_GenomesTAB3 
Exome Variant ServerTAB3
GNOMAD BrowserENSG00000157625
Varsome BrowserTAB3
ACMGTAB3 variants
VarityQ8N5C8
Genomic Variants (DGV)TAB3 [DGVbeta]
DECIPHERTAB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAB3 
Mutations
ICGC Data PortalTAB3 
TCGA Data PortalTAB3 
Broad Tumor PortalTAB3
OASIS PortalTAB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAB3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAB3
Mutations and Diseases : HGMDTAB3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAB3
DgiDB (Drug Gene Interaction Database)TAB3
DoCM (Curated mutations)TAB3
CIViC (Clinical Interpretations of Variants in Cancer)TAB3
Cancer3DTAB3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300480   
Orphanet
DisGeNETTAB3
MedgenTAB3
Genetic Testing Registry TAB3
NextProtQ8N5C8 [Medical]
GENETestsTAB3
Target ValidationTAB3
Huge Navigator TAB3 [HugePedia]
ClinGenTAB3
Clinical trials, drugs, therapy
MyCancerGenomeTAB3
Protein Interactions : CTDTAB3
Pharm GKB GenePA165757406
PharosQ8N5C8
Clinical trialTAB3
Miscellaneous
canSAR (ICR)TAB3
HarmonizomeTAB3
DataMed IndexTAB3
Probes
Litterature
PubMed77 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:07 CEST 2021

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