Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

TAB3 (TGF-beta activated kinase 1 and MAP3K7 binding protein 3)

Identity

Alias_namesMAP3K7IP3
mitogen-activated protein kinase kinase kinase 7 interacting protein 3
Other aliasNAP1
HGNC (Hugo) TAB3
LocusID (NCBI) 257397
Atlas_Id 51346
Location Xp21.2  [Link to chromosome band Xp21]
Location_base_pair Starts at 30827442 and ends at 30889394 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TAB3 (Xp21.2) / DMD (Xp21.2)TAB3 (Xp21.2) / MAGEB2 (Xp21.2)TAB3 Xp21.2 / DMD Xp21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAB3   30681
Cards
Entrez_Gene (NCBI)TAB3  257397  TGF-beta activated kinase 1 and MAP3K7 binding protein 3
AliasesMAP3K7IP3; NAP1
GeneCards (Weizmann)TAB3
Ensembl hg19 (Hinxton)ENSG00000157625 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157625 [Gene_View]  chrX:30827442-30889394 [Contig_View]  TAB3 [Vega]
ICGC DataPortalENSG00000157625
TCGA cBioPortalTAB3
AceView (NCBI)TAB3
Genatlas (Paris)TAB3
WikiGenes257397
SOURCE (Princeton)TAB3
Genetics Home Reference (NIH)TAB3
Genomic and cartography
GoldenPath hg38 (UCSC)TAB3  -     chrX:30827442-30889394 -  Xp21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAB3  -     Xp21.2   [Description]    (hg19-Feb_2009)
EnsemblTAB3 - Xp21.2 [CytoView hg19]  TAB3 - Xp21.2 [CytoView hg38]
Mapping of homologs : NCBITAB3 [Mapview hg19]  TAB3 [Mapview hg38]
OMIM300480   
Gene and transcription
Genbank (Entrez)AK096786 AK297274 AL832071 AY331591 AY331592
RefSeq transcript (Entrez)NM_152787 NM_198312
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAB3
Cluster EST : UnigeneHs.188256 [ NCBI ]
CGAP (NCI)Hs.188256
Alternative Splicing GalleryENSG00000157625
Gene ExpressionTAB3 [ NCBI-GEO ]   TAB3 [ EBI - ARRAY_EXPRESS ]   TAB3 [ SEEK ]   TAB3 [ MEM ]
Gene Expression Viewer (FireBrowse)TAB3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)257397
GTEX Portal (Tissue expression)TAB3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N5C8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N5C8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N5C8
Splice isoforms : SwissVarQ8N5C8
PhosPhoSitePlusQ8N5C8
Domaine pattern : Prosite (Expaxy)CUE (PS51140)    ZF_RANBP2_1 (PS01358)    ZF_RANBP2_2 (PS50199)   
Domains : Interpro (EBI)CUE    Znf_RanBP2   
Domain families : Pfam (Sanger)CUE (PF02845)   
Domain families : Pfam (NCBI)pfam02845   
Domain families : Smart (EMBL)CUE (SM00546)  ZnF_RBZ (SM00547)  
Conserved Domain (NCBI)TAB3
DMDM Disease mutations257397
Blocks (Seattle)TAB3
SuperfamilyQ8N5C8
Human Protein AtlasENSG00000157625
Peptide AtlasQ8N5C8
HPRD06738
IPIIPI00166840   IPI00397561   IPI00644138   
Protein Interaction databases
DIP (DOE-UCLA)Q8N5C8
IntAct (EBI)Q8N5C8
FunCoupENSG00000157625
BioGRIDTAB3
STRING (EMBL)TAB3
ZODIACTAB3
Ontologies - Pathways
QuickGOQ8N5C8
Ontology : AmiGOactivation of MAPK activity  stimulatory C-type lectin receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  protein binding  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  JNK cascade  zinc ion binding  endosome membrane  negative regulation of autophagy  Fc-epsilon receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  
Ontology : EGO-EBIactivation of MAPK activity  stimulatory C-type lectin receptor signaling pathway  MyD88-dependent toll-like receptor signaling pathway  protein binding  cytosol  plasma membrane  I-kappaB kinase/NF-kappaB signaling  JNK cascade  zinc ion binding  endosome membrane  negative regulation of autophagy  Fc-epsilon receptor signaling pathway  positive regulation of NF-kappaB transcription factor activity  extracellular exosome  nucleotide-binding oligomerization domain containing signaling pathway  
Pathways : KEGGNF-kappa B signaling pathway    NOD-like receptor signaling pathway    TNF signaling pathway   
NDEx NetworkTAB3
Atlas of Cancer Signalling NetworkTAB3
Wikipedia pathwaysTAB3
Orthology - Evolution
OrthoDB257397
GeneTree (enSembl)ENSG00000157625
Phylogenetic Trees/Animal Genes : TreeFamTAB3
HOVERGENQ8N5C8
HOGENOMQ8N5C8
Homologs : HomoloGeneTAB3
Homology/Alignments : Family Browser (UCSC)TAB3
Gene fusions - Rearrangements
Fusion : MitelmanTAB3/DMD [Xp21.2/Xp21.2]  
Fusion: TCGATAB3 Xp21.2 DMD Xp21.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAB3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAB3
dbVarTAB3
ClinVarTAB3
1000_GenomesTAB3 
Exome Variant ServerTAB3
ExAC (Exome Aggregation Consortium)TAB3 (select the gene name)
Genetic variants : HAPMAP257397
Genomic Variants (DGV)TAB3 [DGVbeta]
DECIPHERTAB3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAB3 
Mutations
ICGC Data PortalTAB3 
TCGA Data PortalTAB3 
Broad Tumor PortalTAB3
OASIS PortalTAB3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAB3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAB3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch TAB3
DgiDB (Drug Gene Interaction Database)TAB3
DoCM (Curated mutations)TAB3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAB3 (select a term)
intoGenTAB3
Cancer3DTAB3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300480   
Orphanet
MedgenTAB3
Genetic Testing Registry TAB3
NextProtQ8N5C8 [Medical]
TSGene257397
GENETestsTAB3
Target ValidationTAB3
Huge Navigator TAB3 [HugePedia]
snp3D : Map Gene to Disease257397
BioCentury BCIQTAB3
ClinGenTAB3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD257397
Chemical/Pharm GKB GenePA165757406
Clinical trialTAB3
Miscellaneous
canSAR (ICR)TAB3 (select the gene name)
Probes
Litterature
PubMed47 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAB3
EVEXTAB3
GoPubMedTAB3
iHOPTAB3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:58:26 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.