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TAC4 (tachykinin precursor 4)

Identity

Alias (NCBI)EK
HK-1
HK1
PPT-C
HGNC (Hugo) TAC4
HGNC Alias symbHK-1
Pptc
PPT-C
HGNC Alias namehemokinin
HGNC Previous nametachykinin 4
LocusID (NCBI) 255061
Atlas_Id 57342
Location 17q21.33  [Link to chromosome band 17q21]
Location_base_pair Starts at 49838309 and ends at 49848017 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SPOP (17q21.33) / TAC4 (17q21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAC4   16641
Cards
Entrez_Gene (NCBI)TAC4    tachykinin precursor 4
AliasesEK; HK-1; HK1; PPT-C
GeneCards (Weizmann)TAC4
Ensembl hg19 (Hinxton)ENSG00000176358 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176358 [Gene_View]  ENSG00000176358 [Sequence]  chr17:49838309-49848017 [Contig_View]  TAC4 [Vega]
ICGC DataPortalENSG00000176358
TCGA cBioPortalTAC4
AceView (NCBI)TAC4
Genatlas (Paris)TAC4
SOURCE (Princeton)TAC4
Genetics Home Reference (NIH)TAC4
Genomic and cartography
GoldenPath hg38 (UCSC)TAC4  -     chr17:49838309-49848017 -  17q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAC4  -     17q21.33   [Description]    (hg19-Feb_2009)
GoldenPathTAC4 - 17q21.33 [CytoView hg19]  TAC4 - 17q21.33 [CytoView hg38]
ImmunoBaseENSG00000176358
Genome Data Viewer NCBITAC4 [Mapview hg19]  
OMIM607833   
Gene and transcription
Genbank (Entrez)AF515828 AF515829 AF515830 AF515831 AF521560
RefSeq transcript (Entrez)NM_001077503 NM_001077504 NM_001077505 NM_001077506 NM_170685
Consensus coding sequences : CCDS (NCBI)TAC4
Gene ExpressionTAC4 [ NCBI-GEO ]   TAC4 [ EBI - ARRAY_EXPRESS ]   TAC4 [ SEEK ]   TAC4 [ MEM ]
Gene Expression Viewer (FireBrowse)TAC4 [ Firebrowse - Broad ]
GenevisibleExpression of TAC4 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255061
GTEX Portal (Tissue expression)TAC4
Human Protein AtlasENSG00000176358-TAC4 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UU9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UU9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UU9
PhosPhoSitePlusQ86UU9
Domaine pattern : Prosite (Expaxy)TACHYKININ (PS00267)   
Domains : Interpro (EBI)Tachy_Neuro_lke_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TAC4
PDB (RSDB)2MOC   
PDB Europe2MOC   
PDB (PDBSum)2MOC   
PDB (IMB)2MOC   
Structural Biology KnowledgeBase2MOC   
SCOP (Structural Classification of Proteins)2MOC   
CATH (Classification of proteins structures)2MOC   
SuperfamilyQ86UU9
AlphaFold pdb e-kbQ86UU9   
Human Protein Atlas [tissue]ENSG00000176358-TAC4 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q86UU9
IntAct (EBI)Q86UU9
BioGRIDTAC4
STRING (EMBL)TAC4
ZODIACTAC4
Ontologies - Pathways
QuickGOQ86UU9
Ontology : AmiGOextracellular space  extracellular space  inflammatory response  positive regulation of cytosolic calcium ion concentration  tachykinin receptor signaling pathway  regulation of blood pressure  substance P receptor binding  positive regulation of flagellated sperm motility  
Ontology : EGO-EBIextracellular space  extracellular space  inflammatory response  positive regulation of cytosolic calcium ion concentration  tachykinin receptor signaling pathway  regulation of blood pressure  substance P receptor binding  positive regulation of flagellated sperm motility  
NDEx NetworkTAC4
Atlas of Cancer Signalling NetworkTAC4
Wikipedia pathwaysTAC4
Orthology - Evolution
OrthoDB255061
GeneTree (enSembl)ENSG00000176358
Phylogenetic Trees/Animal Genes : TreeFamTAC4
Homologs : HomoloGeneTAC4
Homology/Alignments : Family Browser (UCSC)TAC4
Gene fusions - Rearrangements
Fusion : QuiverTAC4
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAC4
dbVarTAC4
ClinVarTAC4
MonarchTAC4
1000_GenomesTAC4 
Exome Variant ServerTAC4
GNOMAD BrowserENSG00000176358
Varsome BrowserTAC4
ACMGTAC4 variants
VarityQ86UU9
Genomic Variants (DGV)TAC4 [DGVbeta]
DECIPHERTAC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAC4 
Mutations
ICGC Data PortalTAC4 
TCGA Data PortalTAC4 
Broad Tumor PortalTAC4
OASIS PortalTAC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAC4  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAC4
Mutations and Diseases : HGMDTAC4
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAC4
DgiDB (Drug Gene Interaction Database)TAC4
DoCM (Curated mutations)TAC4
CIViC (Clinical Interpretations of Variants in Cancer)TAC4
Cancer3DTAC4
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607833   
Orphanet
DisGeNETTAC4
MedgenTAC4
Genetic Testing Registry TAC4
NextProtQ86UU9 [Medical]
GENETestsTAC4
Target ValidationTAC4
Huge Navigator TAC4 [HugePedia]
ClinGenTAC4
Clinical trials, drugs, therapy
MyCancerGenomeTAC4
Protein Interactions : CTDTAC4
Pharm GKB GenePA134944925
PharosQ86UU9
Clinical trialTAC4
Miscellaneous
canSAR (ICR)TAC4
HarmonizomeTAC4
DataMed IndexTAC4
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:08 CEST 2021

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