TAC4 (tachykinin precursor 4)

2018-02-01 Affiliation

Identity

HGNC

TAC4

LOCATION

17q21.33

LOCUSID

255061

ALIAS

EK,HK-1,HK1,PPT-C

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 255061
MIM: 607833
HGNC: 16641
Ensembl: ENSG00000176358

Variants:

dbSNP: 255061
ClinVar: 255061
TCGA: ENSG00000176358
COSMIC: TAC4

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000176358	ENST00000326219	Q86UU9
ENSG00000176358	ENST00000334568	Q86UU9
ENSG00000176358	ENST00000352793	Q86UU9
ENSG00000176358	ENST00000398154	Q86UU9
ENSG00000176358	ENST00000436235	Q86UU9
ENSG00000176358	ENST00000503603	D6RAS6

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
21368235	2011	The tachykinins substance P and hemokinin-1 favor the generation of human memory Th17 cells by inducing IL-1β, IL-23, and TNF-like 1A expression by monocytes.	23
22554585	2012	Hemokinins modulate endothelium function and promote angiogenesis through neurokinin-1 receptor.	4
17175032	2007	The neuropeptide genes TAC1, TAC3, TAC4, VIP and PACAP(ADCYAP1), and susceptibility to multiple sclerosis.	3
27146034	2016	Expression of Tachykinins and Tachykinin Receptors and Interaction with Kisspeptin in Human Granulosa and Cumulus Cells.	3
27456549	2016	Altered expression of the tachykinins substance P/neurokinin A/hemokinin-1 and their preferred neurokinin 1/neurokinin 2 receptors in uterine leiomyomata.	2
27458061	2016	Human hemokinin-1 promotes migration of melanoma cells and increases MMP-2 and MT1-MMP expression by activating tumor cell NK1 receptors.	1
19081134	2009	Regulatory mechanisms in the differential expression of Hemokinin-1.	0
20580442	2010	Common variants of the neuropeptide expressing tachykinin genes and susceptibility to asthma: a case-control study.	0
20580442	2010	Common variants of the neuropeptide expressing tachykinin genes and susceptibility to asthma: a case-control study.	0
20929541	2010	Expression and function of human hemokinin-1 in human and guinea pig airways.	0

Citation

Dessen P

TAC4 (tachykinin precursor 4)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57342/tac4