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TAC4 (tachykinin 4 (hemokinin))

Identity

Alias_symbol (synonym)HK-1
Pptc
PPT-C
Other aliasEK
HK1
HGNC (Hugo) TAC4
LocusID (NCBI) 255061
Atlas_Id 74456
Location 17q21.33  [Link to chromosome band 17q21]
Location_base_pair Starts at 49838309 and ends at 49848017 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SPOP (17q21.33) / TAC4 (17q21.33)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAC4   16641
Cards
Entrez_Gene (NCBI)TAC4  255061  tachykinin 4 (hemokinin)
AliasesEK; HK-1; HK1; PPT-C
GeneCards (Weizmann)TAC4
Ensembl hg19 (Hinxton)ENSG00000176358 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000176358 [Gene_View]  chr17:49838309-49848017 [Contig_View]  TAC4 [Vega]
ICGC DataPortalENSG00000176358
TCGA cBioPortalTAC4
AceView (NCBI)TAC4
Genatlas (Paris)TAC4
WikiGenes255061
SOURCE (Princeton)TAC4
Genetics Home Reference (NIH)TAC4
Genomic and cartography
GoldenPath hg38 (UCSC)TAC4  -     chr17:49838309-49848017 -  17q21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAC4  -     17q21.33   [Description]    (hg19-Feb_2009)
EnsemblTAC4 - 17q21.33 [CytoView hg19]  TAC4 - 17q21.33 [CytoView hg38]
Mapping of homologs : NCBITAC4 [Mapview hg19]  TAC4 [Mapview hg38]
OMIM607833   
Gene and transcription
Genbank (Entrez)AF515828 AF515829 AF515830 AF515831 AF521560
RefSeq transcript (Entrez)NM_001077503 NM_001077504 NM_001077505 NM_001077506 NM_170685
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAC4
Cluster EST : UnigeneHs.652130 [ NCBI ]
CGAP (NCI)Hs.652130
Alternative Splicing GalleryENSG00000176358
Gene ExpressionTAC4 [ NCBI-GEO ]   TAC4 [ EBI - ARRAY_EXPRESS ]   TAC4 [ SEEK ]   TAC4 [ MEM ]
Gene Expression Viewer (FireBrowse)TAC4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)255061
GTEX Portal (Tissue expression)TAC4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86UU9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86UU9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86UU9
Splice isoforms : SwissVarQ86UU9
PhosPhoSitePlusQ86UU9
Domaine pattern : Prosite (Expaxy)TACHYKININ (PS00267)   
Domains : Interpro (EBI)Tachy_Neuro_lke_CS    Tachykinin_fam   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)TAC4
DMDM Disease mutations255061
Blocks (Seattle)TAC4
PDB (SRS)2MOC   
PDB (PDBSum)2MOC   
PDB (IMB)2MOC   
PDB (RSDB)2MOC   
Structural Biology KnowledgeBase2MOC   
SCOP (Structural Classification of Proteins)2MOC   
CATH (Classification of proteins structures)2MOC   
SuperfamilyQ86UU9
Human Protein AtlasENSG00000176358
Peptide AtlasQ86UU9
HPRD09701
IPIIPI00384258   IPI00791814   IPI00384257   IPI00384256   IPI00816266   IPI00966755   
Protein Interaction databases
DIP (DOE-UCLA)Q86UU9
IntAct (EBI)Q86UU9
FunCoupENSG00000176358
BioGRIDTAC4
STRING (EMBL)TAC4
ZODIACTAC4
Ontologies - Pathways
QuickGOQ86UU9
Ontology : AmiGOreceptor binding  extracellular region  tachykinin receptor signaling pathway  regulation of blood pressure  positive regulation of saliva secretion  
Ontology : EGO-EBIreceptor binding  extracellular region  tachykinin receptor signaling pathway  regulation of blood pressure  positive regulation of saliva secretion  
NDEx NetworkTAC4
Atlas of Cancer Signalling NetworkTAC4
Wikipedia pathwaysTAC4
Orthology - Evolution
OrthoDB255061
GeneTree (enSembl)ENSG00000176358
Phylogenetic Trees/Animal Genes : TreeFamTAC4
HOVERGENQ86UU9
HOGENOMQ86UU9
Homologs : HomoloGeneTAC4
Homology/Alignments : Family Browser (UCSC)TAC4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAC4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAC4
dbVarTAC4
ClinVarTAC4
1000_GenomesTAC4 
Exome Variant ServerTAC4
ExAC (Exome Aggregation Consortium)TAC4 (select the gene name)
Genetic variants : HAPMAP255061
Genomic Variants (DGV)TAC4 [DGVbeta]
DECIPHERTAC4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAC4 
Mutations
ICGC Data PortalTAC4 
TCGA Data PortalTAC4 
Broad Tumor PortalTAC4
OASIS PortalTAC4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAC4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAC4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAC4
DgiDB (Drug Gene Interaction Database)TAC4
DoCM (Curated mutations)TAC4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAC4 (select a term)
intoGenTAC4
Cancer3DTAC4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607833   
Orphanet
MedgenTAC4
Genetic Testing Registry TAC4
NextProtQ86UU9 [Medical]
TSGene255061
GENETestsTAC4
Target ValidationTAC4
Huge Navigator TAC4 [HugePedia]
snp3D : Map Gene to Disease255061
BioCentury BCIQTAC4
ClinGenTAC4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD255061
Chemical/Pharm GKB GenePA134944925
Clinical trialTAC4
Miscellaneous
canSAR (ICR)TAC4 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAC4
EVEXTAC4
GoPubMedTAC4
iHOPTAC4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:40:54 CEST 2017

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