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TADA2A (transcriptional adaptor 2A)

Identity

Alias_namesTADA2L
transcriptional adaptor 2 (ADA2 homolog
Alias_symbol (synonym)ADA2
hADA2
ADA2A
Other aliasKL04P
HGNC (Hugo) TADA2A
LocusID (NCBI) 6871
Atlas_Id 42461
Location 17q12  [Link to chromosome band 17q12]
Location_base_pair Starts at 35766977 and ends at 35837226 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ACACA (17q12) / TADA2A (17q12)PTPRA (20p13) / TADA2A (17q12)TADA2A (17q12) / C17orf78 (17q12)
TADA2A (17q12) / DMD (Xp21.2)TADA2A (17q12) / GDPD4 (11q13.5)TADA2A (17q12) / MAST1 (19p13.2)
TADA2A (17q12) / MED24 (17q21.1)TADA2A (17q12) / MEF2B (19p13.11)TADA2A (17q12) / MYO1D (17q11.2)
TADA2A (17q12) / NECAB3 (20q11.22)TADA2A (17q12) / NLK (17q11.2)THRA (17q21.1) / TADA2A (17q12)
TADA2A 17q12 / MAST1 19p13.2ACACA 17q12 / TADA2A 17q12PTPRA 20p13 / TADA2A 17q12
TADA2A 17q12 / GDPD4 11q13.5TADA2A 17q12 / MED24 17q21.1TADA2A 17q12 / MYO1D 17q11.2
TADA2A 17q12 / NLK 17q11.2THRA 17q21.1 / TADA2A 17q12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TADA2A   11531
Cards
Entrez_Gene (NCBI)TADA2A  6871  transcriptional adaptor 2A
AliasesADA2; ADA2A; KL04P; TADA2L; 
hADA2
GeneCards (Weizmann)TADA2A
Ensembl hg19 (Hinxton)ENSG00000276234 [Gene_View]  chr17:35766977-35837226 [Contig_View]  TADA2A [Vega]
Ensembl hg38 (Hinxton)ENSG00000276234 [Gene_View]  chr17:35766977-35837226 [Contig_View]  TADA2A [Vega]
ICGC DataPortalENSG00000276234
TCGA cBioPortalTADA2A
AceView (NCBI)TADA2A
Genatlas (Paris)TADA2A
WikiGenes6871
SOURCE (Princeton)TADA2A
Genetics Home Reference (NIH)TADA2A
Genomic and cartography
GoldenPath hg19 (UCSC)TADA2A  -     chr17:35766977-35837226 +  17q12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)TADA2A  -     17q12   [Description]    (hg38-Dec_2013)
EnsemblTADA2A - 17q12 [CytoView hg19]  TADA2A - 17q12 [CytoView hg38]
Mapping of homologs : NCBITADA2A [Mapview hg19]  TADA2A [Mapview hg38]
OMIM602276   
Gene and transcription
Genbank (Entrez)AF064094 AF069732 AK022767 AK096371 AK225918
RefSeq transcript (Entrez)NM_001166105 NM_001291918 NM_001488 NM_133439
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010783 NT_187614 NW_004929407
Consensus coding sequences : CCDS (NCBI)TADA2A
Cluster EST : UnigeneHs.500066 [ NCBI ]
CGAP (NCI)Hs.500066
Alternative Splicing GalleryENSG00000276234
Gene ExpressionTADA2A [ NCBI-GEO ]   TADA2A [ EBI - ARRAY_EXPRESS ]   TADA2A [ SEEK ]   TADA2A [ MEM ]
Gene Expression Viewer (FireBrowse)TADA2A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6871
GTEX Portal (Tissue expression)TADA2A
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75478   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75478  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75478
Splice isoforms : SwissVarO75478
PhosPhoSitePlusO75478
Domaine pattern : Prosite (Expaxy)SANT (PS51293)    SWIRM (PS50934)   
Domains : Interpro (EBI)Ada2/TADA2    Homeodomain-like    SANT/Myb    SANT_dom    SWIRM    Znf_ZZ   
Domain families : Pfam (Sanger)Myb_DNA-binding (PF00249)    SWIRM (PF04433)   
Domain families : Pfam (NCBI)pfam00249    pfam04433   
Domain families : Smart (EMBL)SANT (SM00717)  ZnF_ZZ (SM00291)  
Conserved Domain (NCBI)TADA2A
DMDM Disease mutations6871
Blocks (Seattle)TADA2A
PDB (SRS)1X41   
PDB (PDBSum)1X41   
PDB (IMB)1X41   
PDB (RSDB)1X41   
Structural Biology KnowledgeBase1X41   
SCOP (Structural Classification of Proteins)1X41   
CATH (Classification of proteins structures)1X41   
SuperfamilyO75478
Human Protein AtlasENSG00000276234
Peptide AtlasO75478
HPRD03784
IPIIPI00289581   IPI00306347   IPI01015669   
Protein Interaction databases
DIP (DOE-UCLA)O75478
IntAct (EBI)O75478
FunCoupENSG00000276234
BioGRIDTADA2A
STRING (EMBL)TADA2A
ZODIACTADA2A
Ontologies - Pathways
QuickGOO75478
Ontology : AmiGOPCAF complex  DNA binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  transcription cofactor activity  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  chromosome  chromatin remodeling  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  positive regulation of histone acetylation  histone H3 acetylation  
Ontology : EGO-EBIPCAF complex  DNA binding  chromatin binding  transcription factor activity, sequence-specific DNA binding  transcription cofactor activity  transcription coactivator activity  histone acetyltransferase activity  protein binding  nucleus  chromosome  chromatin remodeling  regulation of transcription from RNA polymerase II promoter  transcription from RNA polymerase II promoter  positive regulation of histone acetylation  histone H3 acetylation  
NDEx NetworkTADA2A
Atlas of Cancer Signalling NetworkTADA2A
Wikipedia pathwaysTADA2A
Orthology - Evolution
OrthoDB6871
GeneTree (enSembl)ENSG00000276234
Phylogenetic Trees/Animal Genes : TreeFamTADA2A
HOVERGENO75478
HOGENOMO75478
Homologs : HomoloGeneTADA2A
Homology/Alignments : Family Browser (UCSC)TADA2A
Gene fusions - Rearrangements
Fusion : MitelmanTADA2A/GDPD4 [17q12/11q13.5]  
Fusion : MitelmanTADA2A/MED24 [17q12/17q21.1]  [t(17;17)(q12;q21)]  
Fusion : MitelmanTADA2A/MEF2B [17q12/19p13.11]  [t(17;19)(q12;p13)]  
Fusion : MitelmanTADA2A/MYO1D [17q12/17q11.2]  [t(17;17)(q11;q12)]  
Fusion : MitelmanTADA2A/NLK [17q12/17q11.2]  [t(17;17)(q11;q12)]  
Fusion : MitelmanTHRA/TADA2A [17q21.1/17q12]  [t(17;17)(q12;q21)]  
Fusion: TCGAACACA 17q12 TADA2A 17q12 BLCA
Fusion: TCGAPTPRA 20p13 TADA2A 17q12 LUAD
Fusion: TCGATADA2A 17q12 GDPD4 11q13.5 BRCA
Fusion: TCGATADA2A 17q12 MED24 17q21.1 BRCA
Fusion: TCGATADA2A 17q12 MYO1D 17q11.2 BRCA
Fusion: TCGATADA2A 17q12 NLK 17q11.2 BRCA
Fusion: TCGATHRA 17q21.1 TADA2A 17q12 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTADA2A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TADA2A
dbVarTADA2A
ClinVarTADA2A
1000_GenomesTADA2A 
Exome Variant ServerTADA2A
ExAC (Exome Aggregation Consortium)TADA2A (select the gene name)
Genetic variants : HAPMAP6871
Genomic Variants (DGV)TADA2A [DGVbeta]
DECIPHER (Syndromes)17:35766977-35837226  ENSG00000276234
CONAN: Copy Number AnalysisTADA2A 
Mutations
ICGC Data PortalTADA2A 
TCGA Data PortalTADA2A 
Broad Tumor PortalTADA2A
OASIS PortalTADA2A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTADA2A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTADA2A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TADA2A
DgiDB (Drug Gene Interaction Database)TADA2A
DoCM (Curated mutations)TADA2A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TADA2A (select a term)
intoGenTADA2A
Cancer3DTADA2A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602276   
Orphanet
MedgenTADA2A
Genetic Testing Registry TADA2A
NextProtO75478 [Medical]
TSGene6871
GENETestsTADA2A
Huge Navigator TADA2A [HugePedia]
snp3D : Map Gene to Disease6871
BioCentury BCIQTADA2A
ClinGenTADA2A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6871
Chemical/Pharm GKB GenePA36306
Clinical trialTADA2A
Miscellaneous
canSAR (ICR)TADA2A (select the gene name)
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTADA2A
EVEXTADA2A
GoPubMedTADA2A
iHOPTADA2A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:21:43 CEST 2017

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