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TAF1B (TATA-box binding protein associated factor, RNA polymerase I subunit B)

Identity

Alias_namesTATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kD
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
Alias_symbol (synonym)TAFI63
SL1
RAF1B
RAFI63
Other aliasMGC:9349
HGNC (Hugo) TAF1B
LocusID (NCBI) 9014
Atlas_Id 46234
Location 2p25.1  [Link to chromosome band 2p25]
Location_base_pair Starts at 9843442 and ends at 9934416 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MTHFD2 (2p13.1) / TAF1B (2p25.1)TAF1B (2p25.1) / FOSL2 (2p23.2)TAF1B (2p25.1) / NHEJ1 (2q35)
TAF1B 2p25.1 / FOSL2 2p23.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAF1B   11533
Cards
Entrez_Gene (NCBI)TAF1B  9014  TATA-box binding protein associated factor, RNA polymerase I subunit B
AliasesMGC:9349; RAF1B; RAFI63; SL1; 
TAFI63
GeneCards (Weizmann)TAF1B
Ensembl hg19 (Hinxton)ENSG00000115750 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115750 [Gene_View]  chr2:9843442-9934416 [Contig_View]  TAF1B [Vega]
ICGC DataPortalENSG00000115750
TCGA cBioPortalTAF1B
AceView (NCBI)TAF1B
Genatlas (Paris)TAF1B
WikiGenes9014
SOURCE (Princeton)TAF1B
Genetics Home Reference (NIH)TAF1B
Genomic and cartography
GoldenPath hg38 (UCSC)TAF1B  -     chr2:9843442-9934416 +  2p25.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF1B  -     2p25.1   [Description]    (hg19-Feb_2009)
EnsemblTAF1B - 2p25.1 [CytoView hg19]  TAF1B - 2p25.1 [CytoView hg38]
Mapping of homologs : NCBITAF1B [Mapview hg19]  TAF1B [Mapview hg38]
OMIM604904   
Gene and transcription
Genbank (Entrez)AA746267 AK026521 AK295402 AK308070 AK309751
RefSeq transcript (Entrez)NM_001318976 NM_001318977 NM_005680
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAF1B
Cluster EST : UnigeneHs.584833 [ NCBI ]
CGAP (NCI)Hs.584833
Alternative Splicing GalleryENSG00000115750
Gene ExpressionTAF1B [ NCBI-GEO ]   TAF1B [ EBI - ARRAY_EXPRESS ]   TAF1B [ SEEK ]   TAF1B [ MEM ]
Gene Expression Viewer (FireBrowse)TAF1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9014
GTEX Portal (Tissue expression)TAF1B
Human Protein AtlasENSG00000115750-TAF1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ53T94   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ53T94  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ53T94
Splice isoforms : SwissVarQ53T94
PhosPhoSitePlusQ53T94
Domains : Interpro (EBI)TAF1B/Rrn7    TF_Rrn7_Zf   
Domain families : Pfam (Sanger)zf-RRN7 (PF11781)   
Domain families : Pfam (NCBI)pfam11781   
Conserved Domain (NCBI)TAF1B
DMDM Disease mutations9014
Blocks (Seattle)TAF1B
SuperfamilyQ53T94
Human Protein Atlas [tissue]ENSG00000115750-TAF1B [tissue]
Peptide AtlasQ53T94
HPRD05363
IPIIPI00291416   IPI00807704   IPI00873011   IPI00893654   IPI00893525   IPI00893668   IPI00913908   
Protein Interaction databases
DIP (DOE-UCLA)Q53T94
IntAct (EBI)Q53T94
FunCoupENSG00000115750
BioGRIDTAF1B
STRING (EMBL)TAF1B
ZODIACTAF1B
Ontologies - Pathways
QuickGOQ53T94
Ontology : AmiGORNA polymerase I CORE element sequence-specific DNA binding  transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting  RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  RNA polymerase transcription factor SL1 complex  transcription, DNA-templated  regulation of transcription, DNA-templated  transcription initiation from RNA polymerase I promoter  transcription elongation from RNA polymerase I promoter  termination of RNA polymerase I transcription  TBP-class protein binding  positive regulation of gene expression, epigenetic  metal ion binding  extracellular exosome  RNA polymerase I core factor complex  
Ontology : EGO-EBIRNA polymerase I CORE element sequence-specific DNA binding  transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting  RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript  transcription factor activity, sequence-specific DNA binding  protein binding  nucleus  nucleoplasm  RNA polymerase transcription factor SL1 complex  transcription, DNA-templated  regulation of transcription, DNA-templated  transcription initiation from RNA polymerase I promoter  transcription elongation from RNA polymerase I promoter  termination of RNA polymerase I transcription  TBP-class protein binding  positive regulation of gene expression, epigenetic  metal ion binding  extracellular exosome  RNA polymerase I core factor complex  
NDEx NetworkTAF1B
Atlas of Cancer Signalling NetworkTAF1B
Wikipedia pathwaysTAF1B
Orthology - Evolution
OrthoDB9014
GeneTree (enSembl)ENSG00000115750
Phylogenetic Trees/Animal Genes : TreeFamTAF1B
HOVERGENQ53T94
HOGENOMQ53T94
Homologs : HomoloGeneTAF1B
Homology/Alignments : Family Browser (UCSC)TAF1B
Gene fusions - Rearrangements
Fusion : MitelmanTAF1B/FOSL2 [2p25.1/2p23.2]  
Fusion : MitelmanTAF1B/NHEJ1 [2p25.1/2q35]  [t(2;2)(p25;q35)]  
Fusion: TCGA_MDACCTAF1B 2p25.1 FOSL2 2p23.2 BRCA
Tumor Fusion PortalTAF1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF1B
dbVarTAF1B
ClinVarTAF1B
1000_GenomesTAF1B 
Exome Variant ServerTAF1B
ExAC (Exome Aggregation Consortium)ENSG00000115750
GNOMAD BrowserENSG00000115750
Genetic variants : HAPMAP9014
Genomic Variants (DGV)TAF1B [DGVbeta]
DECIPHERTAF1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF1B 
Mutations
ICGC Data PortalTAF1B 
TCGA Data PortalTAF1B 
Broad Tumor PortalTAF1B
OASIS PortalTAF1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF1B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAF1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAF1B
DgiDB (Drug Gene Interaction Database)TAF1B
DoCM (Curated mutations)TAF1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAF1B (select a term)
intoGenTAF1B
Cancer3DTAF1B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604904   
Orphanet
DisGeNETTAF1B
MedgenTAF1B
Genetic Testing Registry TAF1B
NextProtQ53T94 [Medical]
TSGene9014
GENETestsTAF1B
Target ValidationTAF1B
Huge Navigator TAF1B [HugePedia]
snp3D : Map Gene to Disease9014
BioCentury BCIQTAF1B
ClinGenTAF1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9014
Chemical/Pharm GKB GenePA36308
Clinical trialTAF1B
Miscellaneous
canSAR (ICR)TAF1B (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAF1B
EVEXTAF1B
GoPubMedTAF1B
iHOPTAF1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:37:34 CET 2017

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