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TAF1L (TATA-box binding protein associated factor 1 like)

Identity

Alias (NCBI)TAF(II)210
TAF2A2
HGNC (Hugo) TAF1L
HGNC Previous nameTAF1-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa
 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
LocusID (NCBI) 138474
Atlas_Id 43524
Location 9p21.1  [Link to chromosome band 9p21]
Location_base_pair Starts at 32629454 and ends at 32635669 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)TAF1L   18056
Cards
Entrez_Gene (NCBI)TAF1L    TATA-box binding protein associated factor 1 like
AliasesTAF(II)210; TAF2A2
GeneCards (Weizmann)TAF1L
Ensembl hg19 (Hinxton)ENSG00000122728 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122728 [Gene_View]  ENSG00000122728 [Sequence]  chr9:32629454-32635669 [Contig_View]  TAF1L [Vega]
ICGC DataPortalENSG00000122728
TCGA cBioPortalTAF1L
AceView (NCBI)TAF1L
Genatlas (Paris)TAF1L
SOURCE (Princeton)TAF1L
Genetics Home Reference (NIH)TAF1L
Genomic and cartography
GoldenPath hg38 (UCSC)TAF1L  -     chr9:32629454-32635669 -  9p21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF1L  -     9p21.1   [Description]    (hg19-Feb_2009)
GoldenPathTAF1L - 9p21.1 [CytoView hg19]  TAF1L - 9p21.1 [CytoView hg38]
ImmunoBaseENSG00000122728
Genome Data Viewer NCBITAF1L [Mapview hg19]  
OMIM607798   
Gene and transcription
Genbank (Entrez)AF390562 BC116181 BC116182
RefSeq transcript (Entrez)NM_153809
Consensus coding sequences : CCDS (NCBI)TAF1L
Gene ExpressionTAF1L [ NCBI-GEO ]   TAF1L [ EBI - ARRAY_EXPRESS ]   TAF1L [ SEEK ]   TAF1L [ MEM ]
Gene Expression Viewer (FireBrowse)TAF1L [ Firebrowse - Broad ]
GenevisibleExpression of TAF1L in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)138474
GTEX Portal (Tissue expression)TAF1L
Human Protein AtlasENSG00000122728-TAF1L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZX4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZX4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZX4
PhosPhoSitePlusQ8IZX4
Domaine pattern : Prosite (Expaxy)BROMODOMAIN_1 (PS00633)    BROMODOMAIN_2 (PS50014)   
Domains : Interpro (EBI)Bromodomain    Bromodomain-like_sf    Bromodomain_CS    TAF1    TAF1_animal    TAF_II_230-bd    TAFII-230_TBP-bd_sf    TFIID_sub1_DUF3591    Znf-CCHC_6   
Domain families : Pfam (Sanger)Bromodomain (PF00439)    DUF3591 (PF12157)    TBP-binding (PF09247)    zf-CCHC_6 (PF15288)   
Domain families : Pfam (NCBI)pfam00439    pfam12157    pfam09247    pfam15288   
Domain families : Smart (EMBL)BROMO (SM00297)  
Conserved Domain (NCBI)TAF1L
PDB (RSDB)3HMH    5IGL   
PDB Europe3HMH    5IGL   
PDB (PDBSum)3HMH    5IGL   
PDB (IMB)3HMH    5IGL   
Structural Biology KnowledgeBase3HMH    5IGL   
SCOP (Structural Classification of Proteins)3HMH    5IGL   
CATH (Classification of proteins structures)3HMH    5IGL   
SuperfamilyQ8IZX4
AlphaFold pdb e-kbQ8IZX4   
Human Protein Atlas [tissue]ENSG00000122728-TAF1L [tissue]
HPRD09696
Protein Interaction databases
DIP (DOE-UCLA)Q8IZX4
IntAct (EBI)Q8IZX4
BioGRIDTAF1L
STRING (EMBL)TAF1L
ZODIACTAF1L
Ontologies - Pathways
QuickGOQ8IZX4
Ontology : AmiGODNA binding  histone acetyltransferase activity  protein serine/threonine kinase activity  cellular_component  nucleoplasm  transcription factor TFIID complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  protein phosphorylation  male meiotic nuclear division  RNA polymerase II general transcription initiation factor activity  histone acetylation  TBP-class protein binding  TBP-class protein binding  positive regulation of transcription, DNA-templated  RNA polymerase II preinitiation complex assembly  lysine-acetylated histone binding  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIDNA binding  histone acetyltransferase activity  protein serine/threonine kinase activity  cellular_component  nucleoplasm  transcription factor TFIID complex  regulation of transcription by RNA polymerase II  transcription by RNA polymerase II  transcription initiation from RNA polymerase II promoter  protein phosphorylation  male meiotic nuclear division  RNA polymerase II general transcription initiation factor activity  histone acetylation  TBP-class protein binding  TBP-class protein binding  positive regulation of transcription, DNA-templated  RNA polymerase II preinitiation complex assembly  lysine-acetylated histone binding  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors   
NDEx NetworkTAF1L
Atlas of Cancer Signalling NetworkTAF1L
Wikipedia pathwaysTAF1L
Orthology - Evolution
OrthoDB138474
GeneTree (enSembl)ENSG00000122728
Phylogenetic Trees/Animal Genes : TreeFamTAF1L
Homologs : HomoloGeneTAF1L
Homology/Alignments : Family Browser (UCSC)TAF1L
Gene fusions - Rearrangements
Fusion : QuiverTAF1L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF1L [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF1L
dbVarTAF1L
ClinVarTAF1L
MonarchTAF1L
1000_GenomesTAF1L 
Exome Variant ServerTAF1L
GNOMAD BrowserENSG00000122728
Varsome BrowserTAF1L
ACMGTAF1L variants
VarityQ8IZX4
Genomic Variants (DGV)TAF1L [DGVbeta]
DECIPHERTAF1L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF1L 
Mutations
ICGC Data PortalTAF1L 
TCGA Data PortalTAF1L 
Broad Tumor PortalTAF1L
OASIS PortalTAF1L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF1L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DTAF1L
Mutations and Diseases : HGMDTAF1L
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaTAF1L
DgiDB (Drug Gene Interaction Database)TAF1L
DoCM (Curated mutations)TAF1L
CIViC (Clinical Interpretations of Variants in Cancer)TAF1L
Cancer3DTAF1L
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607798   
Orphanet
DisGeNETTAF1L
MedgenTAF1L
Genetic Testing Registry TAF1L
NextProtQ8IZX4 [Medical]
GENETestsTAF1L
Target ValidationTAF1L
Huge Navigator TAF1L [HugePedia]
ClinGenTAF1L
Clinical trials, drugs, therapy
MyCancerGenomeTAF1L
Protein Interactions : CTDTAF1L
Pharm GKB GenePA134947802
PharosQ8IZX4
Clinical trialTAF1L
Miscellaneous
canSAR (ICR)TAF1L
HarmonizomeTAF1L
DataMed IndexTAF1L
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXTAF1L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:34:10 CEST 2021

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