Atlas of Genetics and Cytogenetics in Oncology and Haematology


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TAF2 (TATA-box binding protein associated factor 2)

Identity

Alias_namesTAF2B
TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD
TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
Alias_symbol (synonym)TAFII150
CIF150
Other aliasMRT40
HGNC (Hugo) TAF2
LocusID (NCBI) 6873
Atlas_Id 74468
Location 8q24.12  [Link to chromosome band 8q24]
Location_base_pair Starts at 119730774 and ends at 119832834 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NAPEPLD (7q22.1) / TAF2 (8q24.12)TAF2 (8q24.12) / ALDH16A1 (19q13.33)TAF2 (8q24.12) / DSCC1 (8q24.12)
TAF2 (8q24.12) / TAF2 (8q24.12)TAF2 ALDH16A1TAF2 DSCC1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)TAF2   11536
Cards
Entrez_Gene (NCBI)TAF2  6873  TATA-box binding protein associated factor 2
AliasesCIF150; MRT40; TAF2B; TAFII150
GeneCards (Weizmann)TAF2
Ensembl hg19 (Hinxton)ENSG00000064313 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064313 [Gene_View]  chr8:119730774-119832834 [Contig_View]  TAF2 [Vega]
ICGC DataPortalENSG00000064313
TCGA cBioPortalTAF2
AceView (NCBI)TAF2
Genatlas (Paris)TAF2
WikiGenes6873
SOURCE (Princeton)TAF2
Genetics Home Reference (NIH)TAF2
Genomic and cartography
GoldenPath hg38 (UCSC)TAF2  -     chr8:119730774-119832834 -  8q24.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)TAF2  -     8q24.12   [Description]    (hg19-Feb_2009)
EnsemblTAF2 - 8q24.12 [CytoView hg19]  TAF2 - 8q24.12 [CytoView hg38]
Mapping of homologs : NCBITAF2 [Mapview hg19]  TAF2 [Mapview hg38]
OMIM604912   615599   
Gene and transcription
Genbank (Entrez)AF026445 AF040701 AF057694 AK001618 AK001909
RefSeq transcript (Entrez)NM_003184
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)TAF2
Cluster EST : UnigeneHs.122752 [ NCBI ]
CGAP (NCI)Hs.122752
Alternative Splicing GalleryENSG00000064313
Gene ExpressionTAF2 [ NCBI-GEO ]   TAF2 [ EBI - ARRAY_EXPRESS ]   TAF2 [ SEEK ]   TAF2 [ MEM ]
Gene Expression Viewer (FireBrowse)TAF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6873
GTEX Portal (Tissue expression)TAF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P1X5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P1X5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P1X5
Splice isoforms : SwissVarQ6P1X5
PhosPhoSitePlusQ6P1X5
Domains : Interpro (EBI)ARM-type_fold    Peptidase_M1_N   
Domain families : Pfam (Sanger)Peptidase_M1 (PF01433)   
Domain families : Pfam (NCBI)pfam01433   
Conserved Domain (NCBI)TAF2
DMDM Disease mutations6873
Blocks (Seattle)TAF2
PDB (SRS)5FUR   
PDB (PDBSum)5FUR   
PDB (IMB)5FUR   
PDB (RSDB)5FUR   
Structural Biology KnowledgeBase5FUR   
SCOP (Structural Classification of Proteins)5FUR   
CATH (Classification of proteins structures)5FUR   
SuperfamilyQ6P1X5
Human Protein AtlasENSG00000064313
Peptide AtlasQ6P1X5
HPRD07060
IPIIPI00328144   IPI00385636   IPI00980494   IPI00976068   IPI00974031   IPI00976679   
Protein Interaction databases
DIP (DOE-UCLA)Q6P1X5
IntAct (EBI)Q6P1X5
FunCoupENSG00000064313
BioGRIDTAF2
STRING (EMBL)TAF2
ZODIACTAF2
Ontologies - Pathways
QuickGOQ6P1X5
Ontology : AmiGOG2/M transition of mitotic cell cycle  transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly  RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly  chromatin binding  protein binding  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  transcription factor TFIID complex  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  proteolysis  metallopeptidase activity  zinc ion binding  response to organic cyclic compound  transcription factor TFTC complex  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcriptional preinitiation complex assembly  regulation of signal transduction by p53 class mediator  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly  RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly  chromatin binding  protein binding  nucleoplasm  transcription factor TFIID complex  transcription factor TFIID complex  transcription factor TFIID complex  transcription from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription initiation from RNA polymerase II promoter  transcription elongation from RNA polymerase II promoter  proteolysis  metallopeptidase activity  zinc ion binding  response to organic cyclic compound  transcription factor TFTC complex  sequence-specific DNA binding  transcription regulatory region DNA binding  positive regulation of transcription from RNA polymerase II promoter  RNA polymerase II transcriptional preinitiation complex assembly  regulation of signal transduction by p53 class mediator  
Pathways : KEGGBasal transcription factors   
NDEx NetworkTAF2
Atlas of Cancer Signalling NetworkTAF2
Wikipedia pathwaysTAF2
Orthology - Evolution
OrthoDB6873
GeneTree (enSembl)ENSG00000064313
Phylogenetic Trees/Animal Genes : TreeFamTAF2
HOVERGENQ6P1X5
HOGENOMQ6P1X5
Homologs : HomoloGeneTAF2
Homology/Alignments : Family Browser (UCSC)TAF2
Gene fusions - Rearrangements
Fusion: TCGATAF2 ALDH16A1
Fusion: TCGATAF2 DSCC1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerTAF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)TAF2
dbVarTAF2
ClinVarTAF2
1000_GenomesTAF2 
Exome Variant ServerTAF2
ExAC (Exome Aggregation Consortium)TAF2 (select the gene name)
Genetic variants : HAPMAP6873
Genomic Variants (DGV)TAF2 [DGVbeta]
DECIPHERTAF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisTAF2 
Mutations
ICGC Data PortalTAF2 
TCGA Data PortalTAF2 
Broad Tumor PortalTAF2
OASIS PortalTAF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICTAF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDTAF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch TAF2
DgiDB (Drug Gene Interaction Database)TAF2
DoCM (Curated mutations)TAF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)TAF2 (select a term)
intoGenTAF2
Cancer3DTAF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604912    615599   
Orphanet22711   
MedgenTAF2
Genetic Testing Registry TAF2
NextProtQ6P1X5 [Medical]
TSGene6873
GENETestsTAF2
Target ValidationTAF2
Huge Navigator TAF2 [HugePedia]
snp3D : Map Gene to Disease6873
BioCentury BCIQTAF2
ClinGenTAF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6873
Chemical/Pharm GKB GenePA36311
Clinical trialTAF2
Miscellaneous
canSAR (ICR)TAF2 (select the gene name)
Probes
Litterature
PubMed55 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineTAF2
EVEXTAF2
GoPubMedTAF2
iHOPTAF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:44:47 CEST 2017

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